The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit

Chemerin partly mediates tumor‐inhibitory effect of all‐ trans retinoic acid via CMKLR 1‐dependent natural killer cell recruitment

(2019) Yan Song et al.   IMMUNOLOGY

Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors

(2019) Raul German Spallanzani et al.   Science Immunology

Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33

(2019) T. Mahlakõiv et al.   Science Immunology

Toward an Understanding of How Immune Cells Control Brown and Beige Adipobiology

(2018) Francesc Villarroya et al.   Cell Metabolism

Chemerin: a multifaceted adipokine involved in metabolic disorders

(2018) Gisela Helfer et al.   JOURNAL OF ENDOCRINOLOGY

Serum chemerin is associated with inflammatory and metabolic parameters-results of a population-based study

(2017) Stephanie Zylla et al.   Obesity

Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation

(2017) Y Lin et al.   ONCOGENE

Perinatal Licensing of Thermogenesis by IL-33 and ST2

(2016) Justin I. Odegaard et al.   CELL

Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling

(2016) Salvatore Fabbiano et al.   Cell Metabolism

Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism

(2016) Helen J. Dranse et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metabolic programming of a beige adipocyte phenotype by genistein

(2016) Sadat A. Aziz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Human 'brite/beige' adipocytes develop from capillary networks and their implantation improves metabolic homeostasis in mice

(2016) So Yun Min et al.   NATURE MEDICINE

Control of brown and beige fat development

(2016) Wenshan Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Myocardin-Related Transcription Factor A Regulates Conversion of Progenitors to Beige Adipocytes

(2015) Meghan E. McDonald et al.   CELL

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation

(2015) Xiaoyan Hui et al.   Cell Metabolism

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Interleukin-33 in Tissue Homeostasis, Injury, and Inflammation

(2015) Ari B. Molofsky et al.   IMMUNITY

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

(2015) Sungsoon Fang et al.   NATURE MEDICINE

Chemerin suppresses murine allergic asthma by inhibiting CCL2 production and subsequent airway recruitment of inflammatory dendritic cells

(2014) L. Zhao et al.   ALLERGY

Contrasting effects of cold acclimation versus obesogenic diets on chemerin gene expression in brown and brite adipose tissues

(2014) Ida R. Hansen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Temperature-Acclimated Brown Adipose Tissue Modulates Insulin Sensitivity in Humans

(2014) Paul Lee et al.   DIABETES

Gpr1 is an active chemerin receptor influencing glucose homeostasis in obese mice

(2014) Jillian L Rourke et al.   JOURNAL OF ENDOCRINOLOGY

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

ChemR23 knockout mice display mild obesity but no deficit in adipocyte differentiation

(2013) Laurie Rouger et al.   JOURNAL OF ENDOCRINOLOGY

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

Differences in the metabolic status of healthy adults with and without active brown adipose tissue

(2013) Qiongyue Zhang et al.   WIENER KLINISCHE WOCHENSCHRIFT

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists

(2012) S. K. Polumuri et al.   JOURNAL OF IMMUNOLOGY

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

Disruption of the Chemokine-Like Receptor-1 (CMKLR1) Gene Is Associated with Reduced Adiposity and Glucose Intolerance

(2011) Matthew C. Ernst et al.   ENDOCRINOLOGY

Chemerin regulates β-cell function in mice

(2011) Michiko Takahashi et al.   Scientific Reports

ChemR23 Dampens Lung Inflammation and Enhances Anti-viral Immunity in a Mouse Model of Acute Viral Pneumonia

(2011) Benjamin Bondue et al.   PLoS Pathogens

Chemerin Exacerbates Glucose Intolerance in Mouse Models of Obesity and Diabetes

(2010) Matthew C. Ernst et al.   ENDOCRINOLOGY

Cold-Induced Adaptive Thermogenesis in Lean and Obese

(2010) Sander L.J. Wijers et al.   Obesity

Chemerin Is a Novel Adipocyte-Derived Factor Inducing Insulin Resistance in Primary Human Skeletal Muscle Cells

(2009) Henrike Sell et al.   DIABETES

C/EBP  and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor   Agonists

(2009) C. Vernochet et al.   MOLECULAR AND CELLULAR BIOLOGY

Synthetic chemerin-derived peptides suppress inflammation through ChemR23

(2008) Jenna L. Cash et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment

(2008) Cristina Albanesi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mast cell–expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis

(2008) Brian A. Zabel et al.   JOURNAL OF EXPERIMENTAL MEDICINE