SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine

(2021) Jerald Sadoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

(2021) Yashavanth Shaan Lakshmanappa et al.   Nature Communications

Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis—A Critical Review of Its Pathogenesis and Treatment

(2021) Jeremy C. McMurray et al.   Frontiers in Pediatrics

BNT162b vaccines protect rhesus macaques from SARS-CoV-2

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SARS-CoV-2 vaccine testing and trials in the pediatric population: biologic, ethical, research, and implementation challenges

(2021) Dan M. Cooper et al.   PEDIATRIC RESEARCH

Racial and Ethnic Disparities in COVID-19 Incidence by Age, Sex, and Period Among Persons Aged

(2021) Miriam E. Van Dyke et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

(2021) David S. Khoury et al.   NATURE MEDICINE

T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals

(2021) Tatjana Bilich et al.   Science Translational Medicine

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy

(2020) Alan D. Curtis et al.   mSphere

Rapid Systematic Review: The Impact of Social Isolation and Loneliness on the Mental Health of Children and Adolescents in the Context of COVID-19

(2020) Maria Elizabeth Loades et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Coronavirus vaccine-associated lung immunopathology-what is the significance?

(2020) Maria Elena Bottazzi et al.   MICROBES AND INFECTION

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

(2020) Neeltje van Doremalen et al.   NATURE

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

(2020) Leora R. Feldstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Well-being of Parents and Children During the COVID-19 Pandemic: A National Survey

(2020) Stephen W. Patrick et al.   PEDIATRICS

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

(2020) Simon P. Graham et al.   npj Vaccines

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

(2020) Takuya Sekine et al.   CELL

Warp Speed for COVID-19 Vaccines: Why are Children Stuck in Neutral?

(2020) Evan J Anderson et al.   CLINICAL INFECTIOUS DISEASES

Distinct clinical and immunological features of SARS–CoV-2–induced multisystem inflammatory syndrome in children

(2020) Pui Y. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

(2020) Edward E. Walsh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

(2020) Evan J. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

(2020) Cheryl Keech et al.   NEW ENGLAND JOURNAL OF MEDICINE

NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

(2020) Mimi Guebre-Xabier et al.   VACCINE

Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults

(2020) Russell M. Viner et al.   JAMA Pediatrics

COVID-19 vaccine development

(2020) Satoshi Kamidani et al.   CURRENT OPINION IN PEDIATRICS

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

(2020) Merryn Voysey et al.   LANCET

Correlates of protection against SARS-CoV-2 in rhesus macaques

(2020) Katherine McMahan et al.   NATURE

MIS-C: early lessons from immune profiling

(2020) Lauren A. Henderson et al.   Nature Reviews Rheumatology

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

(2020) Alicia T. Widge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

(2020) Lindsey R. Baden et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets

(2020) Dhiraj Kumar Singh et al.   Nature Microbiology

Evolution of ocular defects in infant macaques following in utero Zika virus infection

(2020) Glenn Yiu et al.   JCI Insight

A simultaneous oral and intramuscular prime/sublingual boost with a DNA/Modified Vaccinia Ankara viral vector-based vaccine induces simian immunodeficiency virus-specific systemic and mucosal immune responses in juvenile rhesus macaques

(2018) Alan D. Curtis et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques

(2018) Bonnie Phillips et al.   JOURNAL OF VIROLOGY

Glycoconjugate vaccines: Principles and mechanisms

(2018) Rino Rappuoli   Science Translational Medicine

Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques

(2018) Alan D. Curtis et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Co-administration of CH31 broadly neutralizing antibody does not affect development of vaccine-induced anti-HIV-1 envelope antibody responses in infant Rhesus macaques

(2018) Maria Dennis et al.   JOURNAL OF VIROLOGY

An overview of nonhuman primates in aging research

(2017) Julie A. Mattison et al.   EXPERIMENTAL GERONTOLOGY

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

(2017) Samantha Reiss et al.   PLoS One

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+T Cells in Blood

(2016) Jennifer M. Dan et al.   JOURNAL OF IMMUNOLOGY

The clinical development process for a novel preventive vaccine: An overview

(2016) K Singh et al.   Journal of Postgraduate Medicine

Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated with Reduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques

(2016) Kara Jensen et al.   JOURNAL OF VIROLOGY

Dances with cytokines, featuring TFH cells, IL-21, IL-4 and B cells

(2016) Simon Bélanger et al.   NATURE IMMUNOLOGY

Infant HIV Type 1 gp120 Vaccination Elicits Robust and Durable Anti-V1V2 Immunoglobulin G Responses and Only Rare Envelope-Specific Immunoglobulin A Responses

(2014) Genevieve G. Fouda et al.   JOURNAL OF INFECTIOUS DISEASES

Phenotype and functions of memory Tfh cells in human blood

(2014) Nathalie Schmitt et al.   TRENDS IN IMMUNOLOGY

Unbalanced Neonatal CD4+ T-Cell Immunity

(2014) Isabelle Debock et al.   Frontiers in Immunology

The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes

(2013) David J. Dowling et al.   PLoS One

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1–dependent pathways

(2012) Victoria J. Philbin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgA Response in Preterm Neonates Shows Little Evidence of Antigen-Driven Selection

(2012) T. Rogosch et al.   JOURNAL OF IMMUNOLOGY

Challenges in infant immunity: implications for responses to infection and vaccines

(2011) Mercy PrabhuDas et al.   NATURE IMMUNOLOGY

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

(2011) J. R. R. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rhesus Macaque Pediatric SIV Infection Model - A Valuable Tool in Understanding Infant HIV-1 Pathogenesis and for Designing Pediatric HIV-1 Prevention Strategies

(2009) Kristina Abel   CURRENT HIV RESEARCH