Vaccine-driven lung TRM cells provide immunity against Klebsiella via fibroblast IL-17R signaling

Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli

(2021) Hidetada Hirakawa et al.   INFECTION AND IMMUNITY

Harnessing Cross-Reactive CD8+ TRM Cells for Long-Standing Protection Against Influenza A Virus

(2020) Ida Uddbäck et al.   VIRAL IMMUNOLOGY

Long-term maintenance of lung resident memory T cells is mediated by persistent antigen

(2020) Ida Uddbäck et al.   Mucosal Immunology

Host immunology and rational immunotherapy for carbapenem-resistant Klebsiella pneumoniae infection

(2020) Naoki Iwanaga et al.   JCI Insight

Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

(2019) Lijing Su et al.   JOURNAL OF MEDICINAL CHEMISTRY

Progress towards the development of Klebsiella vaccines

(2019) Myeongjin Choi et al.   Expert Review of Vaccines

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study

(2019) Stephanie W Lo et al.   LANCET INFECTIOUS DISEASES

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

(2019) Maria Carolina Amezcua Vesely et al.   CELL

Intradermal or sublingual delivery and heat-labile enterotoxin (LT) proteins shape immunologic outcomes to CFA/I fimbriae-derived subunit antigen vaccine against enterotoxigenic E. coli

(2019) Milton Maciel et al.   INFECTION AND IMMUNITY

Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

(2019) Anukul T. Shenoy et al.   Mucosal Immunology

Generation of protective pneumococcal-specific nasal resident memory CD4+ T cells via parenteral immunization

(2019) Joanne M. O’Hara et al.   Mucosal Immunology

LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice

(2019) E. Valli et al.   Scientific Reports

Fighting Antibiotic-Resistant Klebsiella pneumoniae with “Sweet” Immune Targets

(2018) Roberto Adamo et al.   mBio

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

(2018) Rebekah M. Martin et al.   Frontiers in Cellular and Infection Microbiology

Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells

(2018) Shiki Takamura   Frontiers in Immunology

Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments

(2018) Hiroyuki Yoshitomi et al.   Nature Communications

T Follicular Helper-Like Cells in Inflamed Non-Lymphoid Tissues

(2018) Andreas Hutloff   Frontiers in Immunology

The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT

(2018) John D. Clements et al.   mSphere

Genetic models reveal origin, persistence and non-redundant functions of IL-17–producing γδ T cells

(2018) Inga Sandrock et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pneumococcal conjugate vaccine use for the prevention of pneumococcal disease in adults

(2017) Raul E. Isturiz et al.   Expert Review of Vaccines

Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia

(2017) N MS Smith et al.   Mucosal Immunology

Multidrug-resistant Enterobacteriaceae, Pseudomonas aeruginosa , and vancomycin-resistant Enterococcus : Three major threats to hematopoietic stem cell transplant recipients

(2017) Michael J. Satlin et al.   Transplant Infectious Disease

Pneumocystis -Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity

(2017) Taylor Eddens et al.   Cell Reports

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae

(2016) Kong Chen et al.   Cell Host & Microbe

Genetic tools for identifying and manipulating fibroblasts in the mouse

(2016) Jessica M. Swonger et al.   DIFFERENTIATION

Clinical impact of Gram-negative nonfermenters on adults with community-onset bacteremia in the emergency department

(2015) Chun-Wei Chiu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

The Global Challenge of Carbapenem-Resistant Enterobacteriaceae in Transplant Recipients and Patients With Hematologic Malignancies

(2014) M. J. Satlin et al.   CLINICAL INFECTIOUS DISEASES

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands

(2014) Victoria Y. Alfaro et al.   Frontiers in Pharmacology

T Cell–Mediated Host Immune Defenses in the Lung

(2013) Kong Chen et al.   Annual Review of Immunology

The Th17 family: flexibility follows function

(2013) Rajatava Basu et al.   IMMUNOLOGICAL REVIEWS

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract

(2013) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

(2013) L Silvia Munoz-Price et al.   LANCET INFECTIOUS DISEASES

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Serotype-independent pneumococcal experimental vaccines that induce cellular as well as humoral immunity

(2012) R. Malley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity

(2011) Kong Chen et al.   IMMUNITY

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

(2011) Marcel Wüthrich et al.   JOURNAL OF CLINICAL INVESTIGATION

Escherichia coli Heat-Labile Enterotoxin Promotes Protective Th17 Responses against Infection by Driving Innate IL-1 and IL-23 Production

(2011) C. F. Brereton et al.   JOURNAL OF IMMUNOLOGY

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

(2011) Javier Rangel-Moreno et al.   NATURE IMMUNOLOGY

A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

(2011) Fikri Y Avci et al.   NATURE MEDICINE

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

(2009) Charles E. Egwuagu   CYTOKINE

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE