Interrupted reactions in chemical synthesis

Interrupted Pyridine Hydrogenation: Asymmetric Synthesis of δ‐Lactams

(2021) Tobias Wagener et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reductive Hydroxymethylation of 4‐Heteroarylpyridines

(2020) Hamish B. Hepburn et al.   CHEMISTRY-A EUROPEAN JOURNAL

N‐Centered Radical Directed Remote C−H Bond Functionalization via Hydrogen Atom Transfer

(2020) Gautam Kumar et al.   Chemistry-An Asian Journal

Exploring the Chemistry of Spiroindolenines by Mechanistically-Driven Reaction Development: Asymmetric Pictet–Spengler-type Reactions and Beyond

(2020) Chao Zheng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total Syntheses of (–)‐Minovincine and (–)‐Aspidofractinine Using Chain of Cascade Reactions

(2020) Tibor Soós et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible‐Light‐Mediated Heterocycle Functionalization via Geometrically Interrupted [2+2] Cycloaddition

(2020) Mihai V. Popescu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Interrupted Pummerer Reaction in a Sulfoxide-Catalyzed Oxidative Coupling of 2-Naphthols

(2019) Zhen He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fused Hexacyclic Ring System Through Interrupted iso-Nazarov Initiated Diastereoselective Domino Polycyclization of 2,4-Dienals

(2019) Anne-Sophie Marques et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sulfur-Mediated Allylic C–H Arylation, Epoxidation, and Aziridination

(2019) Hang Luo et al.   JOURNAL OF ORGANIC CHEMISTRY

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors

(2019) Wenhan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,3-Diamine Formation from an Interrupted Hofmann–Löffler Reaction: Iodine Catalyst Turnover through Ritter-Type Amination

(2019) Thomas Duhamel et al.   ACS Catalysis

Iridium-Catalyzed Aza-Spirocyclization of Indole-Tethered Amides: An Interrupted Pictet–Spengler Reaction

(2019) Pablo Gabriel et al.   ORGANIC LETTERS

Recent Advances in the Interrupted Nazarov Reaction

(2019) Anton V. Yadykov et al.   ADVANCED SYNTHESIS & CATALYSIS

The Groebke-Blackburn-Bienaymé Reaction

(2019) André Boltjes et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Interrupted Carbonyl‐Alkyne Metathesis

(2019) Austin T. McFarlin et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of C2 Substituted Benzothiophenes via an Interrupted Pummerer/[3,3]-Sigmatropic/1,2-Migration Cascade of Benzothiophene S -Oxides

(2018) Zhen He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interrupted Baeyer-Villiger Rearrangement: Building A Stereoelectronic Trap for the Criegee Intermediate

(2018) Vera A. Vil' et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Interrupted Pummerer/Nickel-Catalysed Cross-Coupling Sequence

(2018) Miles H. Aukland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interrupted Morita–Baylis–Hillman-Type Reaction of α-Substituted Activated Olefins

(2018) Jing Gu et al.   ORGANIC LETTERS

Site-selective bromination of sp3 C–H bonds

(2018) Shyam Sathyamoorthi et al.   Chemical Science

Intercepted Meyer-Schuster Rearrangements in Organic Synthesis

(2018) Debayan Roy et al.   Asian Journal of Organic Chemistry

Carbonyl–olefin metathesis: a key review

(2018) Lekkala Ravindar et al.   Organic Chemistry Frontiers

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

(2018) Carlo Sambiagio et al.   CHEMICAL SOCIETY REVIEWS

Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island

(2018) Mariateresa Giustiniano et al.   SYNTHESIS-STUTTGART

The reductive C3 functionalization of pyridinium and quinolinium salts through iridium-catalysed interrupted transfer hydrogenation

(2018) Alexandru Grozavu et al.   Nature Chemistry

An Interrupted Schmidt Reaction: C–C Bond Formation Arising from Nitrilium Ion Capture

(2018) Manwika Charaschanya et al.   ORGANIC LETTERS

Assembly of C3a-Peroxylated Pyrroloindolines via Interrupted Witkop Oxidation

(2018) Xunbo Lu et al.   ORGANIC LETTERS

Interrupting Base-Mediated Benzofuran Ring Transformation with Michael Acceptors

(2017) Kolluru Srinivas et al.   JOURNAL OF ORGANIC CHEMISTRY

Diverting Reactive Intermediates Toward Unusual Chemistry: Unexpected Anthranil Products from Davis–Beirut Reaction

(2017) Jie S. Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

Redox-Neutral α-Arylation of Alkyl Nitriles with Aryl Sulfoxides: A Rapid Electrophilic Rearrangement

(2017) Li Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The iso-Nazarov reaction

(2017) Martín J. Riveira et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nazarov reaction: current trends and recent advances in the synthesis of natural compounds and their analogs

(2017) Maxim G. Vinogradov et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Microwave-Assisted Tandem Reactions towards a New Synthesis of Cyclohepta[b]chromene-9,11-diones

(2017) Artur Silva et al.   SYNLETT

Regioselective synthesis of C3 alkylated and arylated benzothiophenes

(2017) Harry J. Shrives et al.   Nature Communications

Redox-Neutral Arylations of Vinyl Cation Intermediates

(2016) Daniel Kaiser et al.   ADVANCED SYNTHESIS & CATALYSIS

The Z-enoate assisted, Meyer–Schuster rearrangement cascade: unconventional synthesis of α-arylenone esters

(2016) Prabhakararao Tharra et al.   CHEMICAL COMMUNICATIONS

Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition Reactions

(2016) Saner Poplata et al.   CHEMICAL REVIEWS

Interrupting the Nazarov Cyclization with Bromine

(2016) Devon J. Schatz et al.   JOURNAL OF ORGANIC CHEMISTRY

Remodeling and Enhancing Schmidt Reaction Pathways in Hexafluoroisopropanol

(2016) Hashim F. Motiwala et al.   JOURNAL OF ORGANIC CHEMISTRY

Metal-Free Approach to Biaryls from Phenols and Aryl Sulfoxides by Temporarily Sulfur-Tethered Regioselective C–H/C–H Coupling

(2016) Tomoyuki Yanagi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium/Yanphos-Catalyzed Asymmetric Interrupted Intramolecular Hydroaminomethylation of trans-1,2-Disubstituted Alkenes

(2016) Caiyou Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (−)-2(S)-Cathafoline, and (−)-Aspidophylline A

(2016) Jesus Moreno et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Free CH–CH-Type Cross-Coupling of Arenes and Alkynes Directed by a Multifunctional Sulfoxide Group

(2016) José A. Fernández-Salas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Mediated Domino Interrupted Iso-Nazarov/Dearomative (3 + 2)-Cycloaddition of Electrophilic Indoles

(2016) Anne-Sophie Marques et al.   ORGANIC LETTERS

Triaryl-Substituted Divinyl Ketones Cyclization: Nazarov Reaction versus Friedel–Crafts Electrophilic Substitution

(2016) Valerii Z. Shirinian et al.   ORGANIC LETTERS

Acid-Catalyzed Activation of Peroxyketals: Tunable Radical Initiation at Ambient Temperature and Below

(2016) Bertrand Schweitzer-Chaput et al.   ORGANIC LETTERS

Acid-Mediated Formation of Radicals or Baeyer-Villiger Oxidation from Criegee Adducts

(2015) Bertrand Schweitzer-Chaput et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,4-Diketones from Cross-Conjugated Dienones: Potassium Permanganate-Interrupted Nazarov Reaction

(2015) Yonghoon Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction

(2015) Corien de Graaff et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Povarov Reaction as a Versatile Strategy for the Preparation of 1, 2, 3, 4-Tetrahydroquinoline Derivatives: An Overview

(2015) Josue S. Bello Forero et al.   CURRENT ORGANIC SYNTHESIS

Electrophilic carbonyl activation: competing condensative cyclizations of tryptamine derivatives

(2015) Fan Liu et al.   TETRAHEDRON LETTERS

Interrupted Imino-Nazarov Cyclization of 1-Aminopentadienyl Cation and Related Cascade Process

(2014) Ronny William et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium

(2014) Di Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acid-Catalyzed Oxidative Radical Addition of Ketones to Olefins

(2014) Bertrand Schweitzer-Chaput et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Interrupted Vinylogous Iso-Nazarov Reaction: Cycloisomerization of Conjugated Trienones to Cyclopenta[b]furan Derivatives

(2014) Martín J. Riveira et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent advance of the application of interrupted Fischer indolization toward bioactive indoline alkaloids

(2014) Yuanzhao Mo et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Oxidative rearrangement of malondialdehyde: substrate scope and mechanistic insights

(2014) Xin Yu et al.   RSC Advances

Understanding the mechanism of the Povarov reaction. A DFT study

(2014) Luis R. Domingo et al.   RSC Advances

Nucleophilicortho-Propargylation of Aryl Sulfoxides: An Interrupted Pummerer/Allenyl Thio-Claisen Rearrangement Sequence

(2013) Andrew J. Eberhart et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A catalytic multicomponent coupling reaction for the enantioselective synthesis of spiroacetals

(2013) Lara Cala et al.   CHEMICAL COMMUNICATIONS

Recent Advances in Organocatalytic Asymmetric Morita–Baylis–Hillman/aza-Morita–Baylis–Hillman Reactions

(2013) Yin Wei et al.   CHEMICAL REVIEWS

Off the Beaten Track: The Use of Secondary Amines in the Ugi Reaction

(2013) Gian Cesare Tron   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Gold-Catalyzed Domino Aminocyclization/1,3-Sulfonyl Migration of N-Substituted N-Sulfonyl-aminobut-3-yn-2-ols to 1-Substituted 3-Sulfonyl-1H-pyrroles

(2013) Wan Teng Teo et al.   JOURNAL OF ORGANIC CHEMISTRY

Interrupted Fischer-Indole Intermediates via Oxyarylation of Alkenyl Boronic Acids

(2013) Heng-Yen Wang et al.   ORGANIC LETTERS

Synthesis of Spirocyclic Indolines by Interruption of the Bischler–Napieralski Reaction

(2013) Jonathan William Medley et al.   ORGANIC LETTERS

Direct Access to Iminosugars through an Interrupted Kondrat'eva Reaction

(2013) Robert Britton et al.   SYNLETT

Catalytic Asymmetric Aza-Diels–Alder Reactions: The Povarov Cycloaddition Reaction

(2013) Mariafrancesca Fochi et al.   SYNTHESIS-STUTTGART

Exploration of Forbidden Povarov Processes as a Source of Unexpected Reactivity: A Multicomponent Mannich-Ritter Transformation

(2012) Sara Preciado et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure–Activity Relationships in Human Toll-like Receptor 8-Active 2,3-Diamino-furo[2,3-c]pyridines

(2012) Deepak B. Salunke et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sulfoxide-TFAA and nucleophile combination as new reagent for aliphatic C–H functionalization at indole 2α-position

(2012) Masanori Tayu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Transition-Metal-Free α-Arylation of β-Keto Amides via an Interrupted Insertion Reaction of Arynes

(2012) Kishor Mohanan et al.   ORGANIC LETTERS

Recent Advances in Amine Synthesis by Catalytic Hydroaminomethylation of Alkenes

(2011) Delphine Crozet et al.   ChemCatChem

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Expeditious Construction of a Carbobicyclic Skeleton via sp3-C−H Functionalization: Hydride Shift from an Aliphatic Tertiary Position in an Internal Redox Process

(2011) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sulfoxide-Mediated α-Arylation of Carbonyl Compounds

(2011) Xueliang Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NucleophilicOrthoAllylation of Aryl and Heteroaryl Sulfoxides

(2011) Andrew J. Eberhart et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt

(2011) Shunxi Dong et al.   ORGANIC LETTERS

Macrocyclization of Linear Peptides Enabled by Amphoteric Molecules

(2010) Ryan Hili et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nazarov Cyclizations of an Allenyl Vinyl Ketone with Interception of the Oxyallyl Cation Intermediate for the Formation of Carbon−Carbon Bonds

(2010) Vanessa M. Marx et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet−Spengler Reaction: Traceless Transfer of Chirality froml-Tryptophan

(2010) John D. Trzupek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel One-Pot, Four-Component Condensation Reaction: An Efficient Approach for the Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazole Derivatives by a Ugi-4CR/aza-Wittig Sequence

(2010) Ali Ramazani et al.   ORGANIC LETTERS

Strategies for Innovation in Multicomponent Reaction Design

(2009) Bruce Ganem   ACCOUNTS OF CHEMICAL RESEARCH

An Interrupted Fischer Indolization Approach toward Fused Indoline-Containing Natural Products

(2009) Ben W. Boal et al.   ORGANIC LETTERS

2-(2,2,2-Trifluoroethylidene)-1,3-dithiane Monoxide as a Trifluoromethylketene Equivalent

(2009) Suguru Yoshida et al.   ORGANIC LETTERS

The Rauhut–Currier reaction: a history and its synthetic application

(2009) Carrie E. Aroyan et al.   TETRAHEDRON

An Interrupted [4+3] Cycloaddition Reaction: A Hydride Shift (Ene Reaction) Intervenes

(2008) Michael Harmata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of aryl-substituted triquinanes through the interrupted Nazarov reaction

(2008) Curtis J. Rieder et al.   CHEMICAL COMMUNICATIONS

An interrupted Ugi reaction enables the preparation of substituted indoxyls and aminoindoles

(2008) John S. Schneekloth et al.   TETRAHEDRON

Beyond the Ugi reaction: less conventional interactions between isocyanides and iminium species

(2008) Laurent El Kaim et al.   TETRAHEDRON