Systemic Treatment with Nicotinamide Riboside Is Protective in Two Mouse Models of Retinal Ganglion Cell Damage

The role of microglia in neuroprogressive disorders: mechanisms and possible neurotherapeutic effects of induced ketosis

(2020) Gerwyn Morris et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3 ) supplementation: A crossover randomized clinical trial

(2020) Flora Hui et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Nicotinamide-Rich Diet in DBA/2J Mice Preserves Retinal Ganglion Cell Metabolic Function as Assessed by PERG Adaptation to Flicker

(2020) Tsung-Han Chou et al.   Nutrients

Axonal Protection by Nicotinamide Riboside via SIRT1-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration

(2020) Yasushi Kitaoka et al.   MOLECULAR NEUROBIOLOGY

Potential Therapeutic Benefit of NAD+ Supplementation for Glaucoma and Age-Related Macular Degeneration

(2020) Gloria Cimaglia et al.   Nutrients

Implications of NAD metabolism in pathophysiology and therapeutics for neurodegenerative diseases

(2019) Keisuke Hikosaka et al.   NUTRITIONAL NEUROSCIENCE

Development and characterization of a new rat ocular hypertension model induced by intracameral injection of conjunctival fibroblasts

(2019) Ayumi Nakagawa et al.   Scientific Reports

IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment

(2019) Josy Augustine et al.   Journal of Neuroinflammation

NAD metabolism: Implications in aging and longevity

(2018) Keisuke Yaku et al.   AGEING RESEARCH REVIEWS

The Emergence of the Nicotinamide Riboside Kinases in the regulation of NAD+ Metabolism

(2018) Rachel S Fletcher et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease

(2018) David C. Schöndorf et al.   Cell Reports

Different Effect of Sox11 in Retinal Ganglion Cells Survival and Axon Regeneration

(2018) Ying Li et al.   Frontiers in Genetics

Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology

(2017) Inas F. Aboobakar et al.   EXPERIMENTAL EYE RESEARCH

Protecting retinal ganglion cells

(2017) T Z Khatib et al.   EYE

Biomarkers for glaucoma: from the lab to the clinic

(2017) N Von Thun Und Hohenstein-Blaul et al.   EYE

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

(2017) Henriët Springelkamp et al.   HUMAN MOLECULAR GENETICS

Glaucoma as a Metabolic Optic Neuropathy

(2017) Pete A. Williams et al.   JOURNAL OF GLAUCOMA

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

(2017) Qiao Huang et al.   MOLECULAR NEUROBIOLOGY

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

NAD + in Aging: Molecular Mechanisms and Translational Implications

(2017) Evandro F. Fang et al.   TRENDS IN MOLECULAR MEDICINE

Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP

(2017) Yiguo Shen et al.   Nature Communications

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma

(2017) Pete A. Williams et al.   Frontiers in Neuroscience

An open-source computational tool to automatically quantify immunolabeled retinal ganglion cells

(2016) Ana C. Dordea et al.   EXPERIMENTAL EYE RESEARCH

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

(2016) Samuel A. J. Trammell et al.   Nature Communications

Medical Management of Glaucoma in the 21st Century from a Canadian Perspective

(2016) Paul Harasymowycz et al.   Journal of Ophthalmology

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

(2016) Samuel A.J. Trammell et al.   Scientific Reports

Complex I Subunit Gene Therapy With NDUFA6 Ameliorates Neurodegeneration in EAE

(2015) V. Talla et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation

(2015) J. L. Cueva Vargas et al.   JOURNAL OF NEUROSCIENCE

Polyphenol-enriched cocoa protects the diabetic retina from glial reaction through the sirtuin pathway

(2015) Diego A. Duarte et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ImagePAD, a novel counting application for the Apple iPad®, used to quantify axons in the Mouse Optic Nerve

(2014) Justin P. Templeton et al.   EXPERIMENTAL EYE RESEARCH

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Rescue of Retinal Function by BDNF in a Mouse Model of Glaucoma

(2014) Luciano Domenici et al.   PLoS One

Clinical Characteristics and Current Treatment of Glaucoma

(2014) L. P. Cohen et al.   Cold Spring Harbor Perspectives in Medicine

How Metabolism Generates Signals during Innate Immunity and Inflammation

(2013) Anne F. McGettrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Exome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosis

(2012) Pei-Wen Chiang et al.   NATURE GENETICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Molecular genetics in glaucoma

(2011) Yutao Liu et al.   EXPERIMENTAL EYE RESEARCH

Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina

(2011) Viswanathan Sivakumar et al.   JOURNAL OF PATHOLOGY

An Optic Nerve Crush Injury Murine Model to Study Retinal Ganglion Cell Survival

(2011) Zhongshu Tang et al.   Jove-Journal of Visualized Experiments

NAD and axon degeneration: From the Wlds gene to neurochemistry

(2010) Jing Wang et al.   Cell Adhesion & Migration

Retinal pathway origins of the pattern ERG of the mouse

(2009) Gen Miura et al.   EXPERIMENTAL EYE RESEARCH

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition