Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism

Absence of Bsep/Abcb11 attenuates MCD‐diet induced hepatic steatosis but aggravates inflammation in mice

(2020) Claudia Daniela Fuchs et al.   LIVER INTERNATIONAL

Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota–bile acid–farnesoid X receptor axis

(2020) Hongshan Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Hepalatide ameliorated progression of nonalcoholic steatohepatitis in mice

(2020) Xue-Jing Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

ApoE deficiency promotes non-alcoholic fatty liver disease in mice via impeding AMPK/mTOR mediated autophagy

(2020) Wanpeng Lu et al.   LIFE SCIENCES

Hepatic HuR modulates lipid homeostasis in response to high-fat diet

(2020) Zhuojun Zhang et al.   Nature Communications

Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease

(2019) Lili Niu et al.   Molecular Systems Biology

Unconjugated and secondary bile acid profiles in response to higher-fat, lower-carbohydrate diet and associated with related gut microbiota: A 6-month randomized controlled-feeding trial

(2019) Yi Wan et al.   CLINICAL NUTRITION

Fish oil alleviates circadian bile composition dysregulation in male mice with NAFLD

(2019) Yang Liu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells

(2019) Ke Fang et al.   BMC Complementary and Alternative Medicine

Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats

(2019) Yingyue Tang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

(2019) Fengjie Huang et al.   Nature Communications

PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

(2019) Rajashree Rana et al.   Molecular Metabolism

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

(2018) Leigh Goedeke et al.   HEPATOLOGY

Bile acid regulation: A novel therapeutic strategy in non-alcoholic fatty liver disease

(2018) Qinwei Yu et al.   PHARMACOLOGY & THERAPEUTICS

Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”

(2018) Yan-Lan Fang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Polyphenol-rich extract from wild Lonicera caerulea berry reduces cholesterol accumulation by mediating the expression of hepatic miR-33 and miR-122, HMGCR, and CYP7A1 in rats

(2018) Suwen Liu et al.   Journal of Functional Foods

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice

(2017) Xiaoyun Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological activities and pharmacokinetic study of hyperoside: A short review

(2017) Aun Raza et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

(2016) Juan P. Arab et al.   HEPATOLOGY

Wheat-bran autolytic peptides containing a branched-chain amino acid attenuate non-alcoholic steatohepatitis via the suppression of oxidative stress and the upregulation of AMPK/ACC in high-fat diet-fed mice

(2016) Takumi Kawaguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanism and Application of Metabolomics

(2016) Xuyun He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD

(2016) Ling Li et al.   JOURNAL OF PROTEOME RESEARCH

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease

(2016) Claudia Fuchs et al.   SEMINARS IN LIVER DISEASE

FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease

(2015) Rotonya M. Carr et al.   Current Atherosclerosis Reports

Cholesterol-Lowering Activity of Sesamin Is Associated with Down-Regulation on Genes of Sterol Transporters Involved in Cholesterol Absorption

(2015) Yin Tong Liang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Genetics, diagnostics and therapeutic advances in NAFLD

(2015) Mary E. Rinella et al.   Nature Reviews Gastroenterology & Hepatology

The human liver-specific proteome defined by transcriptomics and antibody-based profiling

(2014) Caroline Kampf et al.   FASEB JOURNAL

Proteomic Analysis of Solid Pseudopapillary Tumor of the Pancreas Reveals Dysfunction of the Endoplasmic Reticulum Protein Processing Pathway

(2014) Yi Zhu et al.   MOLECULAR & CELLULAR PROTEOMICS

Hypoxic liver injury and cholestasis in critically ill patients

(2013) Thomas Horvatits et al.   Current Opinion in Critical Care

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice

(2013) Iker Uriarte et al.   GUT

Identification of the major metabolites of hyperoside produced by the human intestinal bacteria using the ultra performance liquid chromatography/quadrupole-time-of-flight mass spectrometry

(2013) Jing Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

From evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transport

(2013) Alberto Dávalos et al.   PHARMACOLOGICAL RESEARCH

Bile Acid-Mediated Control of Liver Triglycerides

(2013) Claudia Fuchs et al.   SEMINARS IN LIVER DISEASE

Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

(2013) April D. Lake et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

(2012) Giovanni Musso et al.   PROGRESS IN LIPID RESEARCH

Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis

(2011) Derrick M. Van Rooyen et al.   GASTROENTEROLOGY

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

(2009) Lauren N. Bell et al.   HEPATOLOGY

The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression

(2009) Munechika Enjoji et al.   Hepatology International

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON