Autophagy Promotes the Survival of Adipose Mesenchymal Stem/Stromal Cells and Enhances Their Therapeutic Effects in Cisplatin-Induced Liver Injury via Modulating TGF-β1/Smad and PI3K/AKT Signaling Pathways

Cyanidin‐3‐ O ‐glucoside and cisplatin inhibit proliferation and downregulate the PI3K/AKT/mTOR pathway in cervical cancer cells

(2021) Xu Li et al.   JOURNAL OF FOOD SCIENCE

Liver sinusoidal endothelial cells are implicated in multiple fibrotic mechanisms

(2021) Heming Ma et al.   MOLECULAR BIOLOGY REPORTS

Macrophages contribute to liver repair after monocrotaline-induced liver injury via SDF-1/CXCR4

(2021) Fumisato Otaka et al.   Experimental and Therapeutic Medicine

Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice

(2021) Mihai Bogdan Preda et al.   Cell Death & Disease

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

miR-29a-3p suppresses hepatic fibrosis pathogenesis by modulating hepatic stellate cell proliferation via targeting PIK3R3 gene expression

(2020) Juan Fu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer

(2020) Yingying Kou et al.   Frontiers in Pharmacology

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

MicroRNA-101 suppresses liver fibrosis by downregulating PI3K/Akt/mTOR signaling pathway

(2019) Yang Lei et al.   Clinics and Research in Hepatology and Gastroenterology

lncRNA GAS5 Restrains CCl4-Induced Hepatic Fibrosis by Targeting miR-23a through the PTEN/PI3K/Akt Signaling Pathway

(2019) Zhiheng Dong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non‑alcoholic fatty liver disease mouse model

(2019) Yulei Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Modulating autophagy in mesenchymal stem cells effectively protects against hypoxia- or ischemia-induced injury

(2019) Chenxia Hu et al.   Stem Cell Research & Therapy

Molecular basis for class side effects associated with PI3K/AKT/mTOR pathway inhibitors

(2019) Ying Zhang et al.   Expert Opinion on Drug Metabolism & Toxicology

Panax ginseng is superior to vitamin E as a hepatoprotector against cyclophosphamide-induced liver damage

(2019) Ahmed Abdelfattah-Hassan et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Overview of cisplatin-induced neurotoxicity and ototoxicity, and the protective agents

(2019) Neife Aparecida Guinaim dos Santos et al.   FOOD AND CHEMICAL TOXICOLOGY

Modulation of autophagy as new approach in mesenchymal stem cell-based therapy

(2018) Jelena Jakovljevic et al.   BIOMEDICINE & PHARMACOTHERAPY

TGF-β1/p53 signaling in renal fibrogenesis

(2018) Stephen P. Higgins et al.   CELLULAR SIGNALLING

Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation

(2018) Xihang Chen et al.   Stem Cells International

The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

(2018) Xiao-jie Mi et al.   Scientific Reports

Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats

(2018) Faisal A. Alzahrani et al.   Stem Cells International

Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury

(2018) Maria Ruart et al.   JOURNAL OF HEPATOLOGY

Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling

(2018) Shanshan Wang et al.   Cell Death & Disease

Silencing long non-coding RNA ROR improves sensitivity of non-small-cell lung cancer to cisplatin resistance by inhibiting PI3K/Akt/mTOR signaling pathway

(2017) Hui Shi et al.   TUMOR BIOLOGY

Tripchlorolide induces autophagy in lung cancer cells by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin sensitivity in A549/DDP cells

(2017) Li-Min Chen et al.   Oncotarget

Stromal cell-derived factor-1 (SDF-1) as a target in liver diseases

(2016) Anke Liepelt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effect of resveratrol and rosuvastatin on experimental diabetic nephropathy in rats

(2016) Mohamed M.A. Hussein et al.   BIOMEDICINE & PHARMACOTHERAPY

Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

(2016) Yoshihiro Seto et al.   BMC CANCER

The rationale for targeting TGF-β in chronic liver diseases

(2016) Gianluigi Giannelli et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Patient-reported outcomes in the evaluation of toxicity of anticancer treatments

(2016) Massimo Di Maio et al.   Nature Reviews Clinical Oncology

Involvement of TGF-β1/Smad3 Signaling in Carbon Tetrachloride-Induced Acute Liver Injury in Mice

(2016) Liman Niu et al.   PLoS One

Autophagy Plays a Protective Role in Tumor Necrosis Factor-α-Induced Apoptosis of Bone Marrow-Derived Mesenchymal Stem Cells

(2016) Rui Yang et al.   STEM CELLS AND DEVELOPMENT

How to Improve the Survival of Transplanted Mesenchymal Stem Cell in Ischemic Heart?

(2016) Liangpeng Li et al.   Stem Cells International

Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease

(2015) Kyoung-Woon Kim et al.   Stem Cell Research & Therapy

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

(2014) You-Tong Wu et al.   Autophagy

EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling

(2014) Sang-A Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting PI3K/Akt/mTOR Signaling in Cancer

(2014) Camillo Porta et al.   Frontiers in Oncology

Autophagy in stem cells

(2013) Jun-Lin Guan et al.   Autophagy

New Insights Into the Role of Sequestosome 1/p62 Mutant Proteins in the Pathogenesis of Paget's Disease of Bone

(2013) Sarah L. Rea et al.   ENDOCRINE REVIEWS

EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

(2013) Rossella Pellegrino et al.   HEPATOLOGY

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update

(2012) Neife Aparecida Guinaim dos Santos et al.   ARCHIVES OF TOXICOLOGY

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

(2012) Avijit Majumdar et al.   Nature Reviews Gastroenterology & Hepatology

Autophagy Activation: A Novel Mechanism of Atorvastatin to Protect Mesenchymal Stem Cells from Hypoxia and Serum Deprivation via AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

(2012) Qian Zhang et al.   STEM CELLS AND DEVELOPMENT

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

Rapamycin passes the torch: a new generation of mTOR inhibitors

(2011) Don Benjamin et al.   NATURE REVIEWS DRUG DISCOVERY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair

(2010) Yufang Shi et al.   CELL RESEARCH

Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype

(2010) Bradley T Estes et al.   Nature Protocols

SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model

(2008) Ye Wang et al.   BRAIN RESEARCH

Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt

(2008) X Yang et al.   BRITISH JOURNAL OF CANCER

Roles of TGF-β family signaling in stem cell renewal and differentiation

(2008) Tetsuro Watabe et al.   CELL RESEARCH

Adipose-derived stem cells: Isolation, expansion and differentiation☆

(2008) B BUNNELL et al.   METHODS

Selection of agents for prevention of cisplatin-induced hepatotoxicity

(2008) Yingjun Liao et al.   PHARMACOLOGICAL RESEARCH

Age-Related Reference Intervals of the Main Biochemical and Hematological Parameters in C57BL/6J, 129SV/EV and C3H/HeJ Mouse Strains

(2008) Cristina Mazzaccara et al.   PLoS One