Article
Multidisciplinary Sciences
Christian Peters, Songwei He, Federica Fermani, Hansol Lim, Wenyu Ding, Christian Mayer, Ruediger Klein
Summary: Using single-nucleus RNA sequencing, this study identifies nine clusters of cells in the central amygdala (CeA) and finds that certain cells are associated with appetitive and aversive behaviors. The study focuses on serotonin receptor 2a (Htr2a)-expressing neurons (CeAHtr2a) in the CeA that promote feeding and finds that these neurons are activated by fasting, ghrelin, and the presence of food. They also project to the parabrachial nucleus, inhibiting target neurons and influencing feeding behavior.
Article
Biotechnology & Applied Microbiology
Martin S. Espinosa, Jorge G. Hill, Eduardo G. Virla
Summary: This study found that providing different food sources such as pollen to the pincer wasp can significantly increase female longevity, fecundity, and parasitism rates while reducing host-feeding activities. However, it may also lead to more self-superparasitism occurrences. This highlights the importance of food sources in enhancing parasitoid performance and the potential benefits for artificial rearing and field releases.
BIOLOGICAL CONTROL
(2021)
Article
Fisheries
Wenqiang Wang, Peng Yang, Chaoqun He, Shuyan Chi, Songlin Li, Kangsen Mai, Fei Song
Summary: This study found that different levels of methionine in the diet can affect growth performance and metabolism in fish species, with methionine supplementation increasing amino acid concentrations and activating the GH-IGF signaling pathway to enhance fish growth.
AQUACULTURE REPORTS
(2021)
Article
Agriculture, Dairy & Animal Science
Sonia Valladares, Miquel Planas
Summary: Stable isotopes were used to assess the assimilation of food in early juvenile seahorses reared under two feeding conditions, with copepods being more efficiently assimilated than Artemia. The stable carbon isotopes could trace the consumption and assimilation of preys by juvenile seahorses, offering insights into nutrient processes and ontogeny in the early life stages of the species. The study highlights the importance of nutrient assimilation in the initial survival and growth of juvenile seahorses.
Editorial Material
Psychology, Developmental
Megan Van Hoorn, Mary Beth Feuling, Kim Allen, Rashelle Berry, Shonda Brown, Christine M. Sullivan, Praveen S. Goday
Summary: This paper discusses the issue of pediatric feeding disorder and lack of dietary diversity in children, providing an understanding and measurement method for this problem, and proposing an overview of a management strategy to improve dietary diversity.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Nutrition & Dietetics
Ana-Catarina Pinho-Gomes, Asha Kaur, Peter Scarborough, Mike Rayner
Summary: The study found good agreement between the 2005 and 2018 versions of the NPM and the EWG in assessing the healthiness of diets in the UK population.
Review
Cell Biology
Aleksandra Dabrowska, Juhi Kumar, Charalampos Rallis
Summary: Cellular and animal models have played a crucial role in understanding the relationship between diet, nutrient-response signaling pathways, and lifespan regulation. Recent advancements in drug treatments, mutagenesis, and high-throughput screens have provided valuable insights into cellular metabolism, development, and aging. Scientists are now focusing on characterizing growth and stress pathways to identify interventions for healthy aging and age-related diseases.
Review
Agriculture, Multidisciplinary
Xudong Zhang, Andreas Blennow, Mario Jekle, Christian Zoerb
Summary: Mineral nutrients play a crucial role in the biosynthesis and accumulation of storage biopolymers, directly affecting grain yield and quality. We propose that extensive mineral nutrients have significant effects on storage protein synthesis, content, and composition, thereby determining physicochemical properties and food quality, especially in the context of climate change.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Akiko Maruko, Koichi M. Iijima, Kanae Ando
Summary: This study investigates the molecular pathways involved in the generation of daily feeding patterns in Drosophila. The results show that quasimodo (qsm) and CLK play important roles in regulating feeding rhythms, and the generation of feeding/fasting episodes is independent of the molecular clock machinery.
Article
Agriculture, Multidisciplinary
Anka Trajkovska Petkoska, Anita Trajkovska-Broach
Summary: The Mediterranean diet aligns well with the UN's Sustainable Development Goals, making it a healthy and sustainable way of living.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Endocrinology & Metabolism
Maria E. de Sousa, Daniela O. Gusmao, Willian O. dos Santos, Henrique T. Moriya, Felipe F. de Lima, Edward O. List, John J. Kopchick, Jose Donato Jr
Summary: GH receptor is expressed in the arcuate nucleus of the hypothalamus and modulates GH secretion. Short-term fasting and prolonged food restriction have different effects on the pattern of GH secretion, independent of GHR signaling in ARH(AgRP/NPY) neurons.
JOURNAL OF NEUROENDOCRINOLOGY
(2023)
Article
Marine & Freshwater Biology
Xi Wang, Bao-Liang Liu, Xian-Hong Zhang, Shu-Quan Cao, Xiao-Qiang Gao, Kui-Feng Zhao, Chuan-Xin Zhang
Summary: Excessive levels of manganese in water can have detrimental effects on the growth and development of fish. This study investigated the effects of Mn2+ exposure on the growth performance, hormone axes, and neurotransmitters of Yunlong groupers. High concentrations of Mn2+ significantly reduced growth parameters and increased mortality rates. Mn2+ exposure also disrupted the GH/IGF and HPT axes, as well as dopamine and serotonin synthesis and metabolism.
AQUATIC TOXICOLOGY
(2023)
Article
Endocrinology & Metabolism
Kathryn M. Spitler, Shwetha K. Shetty, Emily M. Cushing, Kelli L. Sylvers-Davie, Brandon S. J. Davies
Summary: Hepatocyte-specific loss of ANGPTL4 does not improve triglyceride phenotypes during high-fat feeding, but these mice show improved glucose tolerance after chronic high-fat diet. Additionally, Angptl4(LivKO) mice have decreased fasting plasma triglyceride levels after an 18-h fast, but not after a 6-h fast.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Nutrition & Dietetics
Martina Vitale, Shannon Crossland, Jackie Shinwell, Paul B. Stretesky, Margaret Anne Defeyter, Iain Andrew Brownlee
Summary: A large proportion of children in the UK are at risk of food insecurity during school holidays. The government-funded Holiday Activities and Food (HAF) programme offers free holiday clubs that provide at least one healthy meal per day. This study evaluates the nutritional quality of food provided at HAF holiday clubs, specifically hot/cold and vegetarian/non-vegetarian meals. The findings suggest potential areas for improvement in the provision of food at HAF holiday clubs, particularly for adolescents aged 11-18.
Article
Oncology
Amy L. Shaver, Theresa A. Tufuor, Jing Nie, Shauna Ekimura, Keri Marshall, Susan Hazels Mitmesser, Katia Noyes
Summary: The study investigated the prevalence and cost-effectiveness of dietary supplementation in cancer survivors, finding that supplementation can reduce hospitalization rates and improve quality of life. Further research is needed to determine the specific effects of supplementation on long-term outcomes by cancer type.
Review
Endocrinology & Metabolism
Marina Caputo, Chiara Mele, Alice Ferrero, Ilaria Leone, Tommaso Daffara, Paolo Marzullo, Flavia Prodam, Gianluca Aimaretti
Summary: Aging and age-related diseases are hot topics of current research, influenced by genetic and environmental factors. Understanding the role of the endocrine system in aging is crucial for early assessment of endocrine function in aging individuals.
NEUROENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Alessandro Nuzzo, Andrea Brignoli, Maria C. Ponziani, Marco Zavattaro, Flavia Prodam, Luigi M. Castello, Gian C. Avanzi, Paolo Marzullo, Gianluca Aimaretti
Summary: This study retrospectively analyzed the risk of hospitalization and mortality within 1 year after severe hypoglycemia in diabetic patients, finding that severe hypoglycemia is associated with increased risk of hospitalization and mortality, especially in elderly patients. Furthermore, it may predict future cardiovascular events in diabetic patients with pre-existing heart disease and obesity.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Nutrition & Dietetics
Valentina Antoniotti, Daniele Spadaccini, Roberta Ricotti, Deborah Carrera, Silvia Savastio, Filipa Patricia Goncalves Correia, Marina Caputo, Erica Pozzi, Simonetta Bellone, Ivana Rabbone, Flavia Prodam
Summary: This study evaluated adherence to the Mediterranean diet among children and adolescents with type 1 diabetes and found that adherence was poor in a significant portion of the subjects. Additionally, adherence was associated with BMI, glucose control, and metabolic control. Promoting the Mediterranean diet, particularly having a healthy breakfast, is important for managing and improving glucose and metabolic control in patients with type 1 diabetes.
Article
Nutrition & Dietetics
Edda Cava, Paolo Marzullo, Deborah Farinelli, Alessandra Gennari, Chiara Saggia, Sergio Riso, Flavia Prodam
Summary: Breast cancer survivors often experience weight gain and fat accumulation after diagnosis, which decreases survival rate and increases the risk of recurrence. Multiple interventions, including healthy dietary patterns, have been studied to reduce the risk of second primary cancer or breast cancer recurrence and mortality.
Article
Nutrition & Dietetics
Laura Salvadori, Maria Laura Belladonna, Beatrice Castiglioni, Martina Paiella, Eleonora Panfili, Tommaso Manenti, Catia Ercolani, Luca Cornioli, Sara Chiappalupi, Giulia Gentili, Massimiliano Leigheb, Guglielmo Sorci, Michela Bosetti, Nicoletta Filigheddu, Francesca Riuzzi
Summary: The dietary product KYMASIN UP has been found to reduce osteoclast formation and activity, as well as regulate osteoclastogenic markers. Withania somnifera, the main ingredient of the product, plays a significant role in inhibiting osteoclastogenesis. Furthermore, KYMASIN UP maintains physiological release of osteoprotegerin and enhances calcium mineralization. These findings suggest that KYMASIN UP may help reverse age-related functional decline of bone tissue.
Article
Hematology
Celia Cordero-Sanchez, Emanuela Pessolano, Beatrice Riva, Mauro Vismara, Silvia Maria Grazia Trivigno, Nausicaa Clemente, Silvio Aprile, Federico Alessandro Ruffinatti, Paola Portararo, Nicoletta Filigheddu, Ivan Zaggia, Irene P. Bhela, Marta Serafini, Tracey Pirali, Mario P. Colombo, Mauro Torti, Sabina Sangaletti, Alessandra Bertoni, Armando A. Genazzani
Summary: Store-operated Ca2+-entry is a cellular mechanism associated with ultra-rare diseases. In a mouse model with the STIM1 p.I115F mutation, it was found that CIC-39Na can restore platelet number and counteract abnormal bleeding, providing a new pharmacological treatment strategy for thrombocytopenia in these diseases.
Article
Endocrinology & Metabolism
F. Prodam, M. Caputo, M. Romanisio, S. Brasili, M. Zavattaro, M. T. Sama, A. Ferrero, S. Costelli, F. R. Lenzi, A. Petri, E. Basso, S. Bellone, G. Aimaretti
Summary: This study evaluated the clinical and epidemiological characteristics of outpatients transitioning from Pediatric Endocrine Department to Adult Endocrine Department in a tertiary center, as well as the features of the transition process and predictors of drop-out. The findings showed that the patients were heterogeneous, with different ages, follow-up durations, and types of endocrine diseases. The number of visits was associated with the number and type of endocrine diseases, and adherence to follow-up was predicted by thyroid disorders and multiple comorbidities. A study exploring a specific transition plan for chronic endocrine diseases.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Pediatrics
Valentina Mancioppi, Valentina Antoniotti, Arianna Solito, Elisabetta Mingoia, Alice Monzani, Giulia Genoni, Ivana Rabbone, Flavia Prodam, Simonetta Bellone
Summary: This study investigated subclinical hypothyroidism in newborns and observed the changes in thyroid hormone levels over time until four years of age. The results showed that more than half of the newborns did not require treatment and had either normal or slightly increased thyroid function. The study also suggested the importance of long-term follow-up to monitor thyroid hormone levels.
Article
Endocrinology & Metabolism
Cristina Partenope, Quincy Pedranzini, Antonella Petri, Ivana Rabbone, Flavia Prodam, Simonetta Bellone
Summary: The report presents a case of a 16-year-old boy who developed polyuria, polydipsia, and weight loss after receiving the COVID-19 vaccine. Diagnosis revealed neuroinfundibulohypophysitis, a rare disorder characterized by inflammation of the pituitary gland and stalk. Further studies are needed to explore the possible causal link between the COVID-19 vaccine and AVP deficiency.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
M. Caputo, T. Daffara, A. Ferrero, M. Romanisio, E. Monti, C. Mele, M. Zavattaro, S. Tricca, A. Siani, A. Clemente, C. Palumbo, S. De Cilla, A. Carriero, A. Volpe, P. Marzullo, G. Aimaretti, F. Prodam
Summary: The aim of this study was to identify risk factors for morphological changes in adrenal incidentalomas (AIs) during follow-up. High body weight, dehydroepiandrosterone sulfate (DHEAS), and direct renin concentration (DRC) were found to be associated with tumor enlargement, while aldosterone levels were lower in these cases. Additionally, glaucoma and dysglycemia had a higher prevalence in patients with tumor enlargement and were identified as independent predictors.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Endocrinology & Metabolism
Martina Romanisio, Rosa Pitino, Alice Ferrero, Francesca Pizzolitto, Samuele Costelli, Valentina Antoniotti, Paolo Marzullo, Gianluca Aimaretti, Flavia Prodam, Marina Caputo
Summary: This study evaluated metabolic comorbidities in surgically treated acromegalic patients and found that the discrepancy between GH and IGF-1 levels does not appear to be a risk factor for their presence or persistence. Further extended studies are needed to confirm these results in the long term.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Valentina Mancioppi, Tommaso Daffara, Martina Romanisio, Giovanni Ceccarini, Caterina Pelosini, Ferruccio Santini, Simonetta Bellone, Simona Mellone, Alessio Baricich, Ivana Rabbone, Gianluca Aimaretti, Baris Akinci, Mara Giordano, Flavia Prodam
Summary: This article describes a rare lipodystrophy syndrome called congenital generalized lipodystrophy type 4 (CGL4), which is caused by mutations in the PTRF gene. Two early childhood patients presented with features such as reduced subcutaneous fat, muscular hypertrophy, distinctive facial features, myopathy, and atlantoaxial instability. Blood tests showed elevated CK and triglyceride levels, and undetectable leptin and adiponectin concentrations.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
Edda Cava, Daniele Spadaccini, Gianluca Aimaretti, Paolo Marzullo, Beatrice Cavigiolo, Deborah Farinelli, Alessandra Gennari, Chiara Saggia, Maria Grazia Carbonelli, Sergio Riso, Flavia Prodam
Summary: This retrospective observational cohort study aimed to assess the impact of a Mediterranean diet on weight and anthropometric changes in women completing active breast cancer treatment. The study found that implementing a Mediterranean diet can lead to weight and anthropometric improvements in breast cancer survivors. However, further research is necessary to explore the long-term effects of weight loss on these individuals and consider specific predictors of dropout.
Article
Endocrinology & Metabolism
Valentina Antoniotti, Martina Amore, Marina Caputo, Chiara Fania, Valentina Mancioppi, Gloria Casoli, Sabrina Tini, Alessandro Antonioli, Gianluca Aimaretti, Ivana Rabbone, Simonetta Bellone, Flavia Prodam
Summary: This study aimed to explore the relationship between childhood obesity and insulin resistance, glucose alterations, hypertension, and the renin-angiotensin-aldosterone system (RAAS). The results showed that 87.6% of pediatric obesity patients had hypertension, and those with glucose alterations were more likely to have hypertension. Blood pressure levels were positively correlated with glucose alterations, and insulin sensitivity was lower in hypertensive individuals. The study highlights the importance of close clinical surveillance in specific risk categories.
JOURNAL OF THE ENDOCRINE SOCIETY
(2023)
Article
Endocrinology & Metabolism
Valentina Antoniotti, Simonetta Bellone, Filipa Patricia Goncalves Correia, Caterina Peri, Sabrina Tini, Roberta Ricotti, Valentina Mancioppi, Mara Gagliardi, Daniele Spadaccini, Marina Caputo, Marco Corazzari, Flavia Prodam
Summary: This study aimed to evaluate the relationship between markers of endoplasmic reticulum stress and metabolic alterations in children and adolescents with obesity. The findings suggest that PDIA3 and CALR may be early markers of obesity and metabolic syndrome risk.
FRONTIERS IN ENDOCRINOLOGY
(2022)
