The Multifaceted Regulation of SnRK2 Kinases

Reciprocal regulation between the negative regulator PP2CG1 phosphatase and the positive regulator OST1 kinase confers cold response in Arabidopsis

(2021) Jian Lv et al.   Journal of Integrative Plant Biology

Initiation and amplification of SnRK2 activation in abscisic acid signaling

(2021) Zhen Lin et al.   Nature Communications

Cellular Phosphorylation Signaling and Gene Expression in Drought Stress Responses: ABA-Dependent and ABA-Independent Regulatory Systems

(2021) Fumiyuki Soma et al.   Plants-Basel

Open stomata 1 exhibits dual serine/threonine and tyrosine kinase activity in regulating abscisic acid signaling

(2021) Yun Shang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Persulfidation-induced structural change in SnRK2.6 establishes intramolecular interaction between phosphorylation and persulfidation

(2021) Sisi Chen et al.   Molecular Plant

Pepper ubiquitin‐specific protease, CaUBP12, positively modulates dehydration resistance by enhancing CaSnRK2.6 stability

(2021) Chae Woo Lim et al.   PLANT JOURNAL

Hydrogen Sulfide Positively Regulates Abscisic Acid Signaling through Persulfidation of SnRK2.6 in Guard Cells

(2020) Sisi Chen et al.   Molecular Plant

MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response

(2020) Yohei Takahashi et al.   Nature Communications

A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants

(2020) Zhen Lin et al.   Nature Communications

Type A2 BTB Members Decrease the ABA Response during Seed Germination by Affecting the Stability of SnRK2.3 in Arabidopsis

(2020) Guohua Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Arabidopsis Raf‐like kinases act as positive regulators of subclass III SnRK2 in osmostress signaling

(2020) Shohei Katsuta et al.   PLANT JOURNAL

Plant Raf-like kinases regulate the mRNA population upstream of ABA-unresponsive SnRK2 kinases under drought stress

(2020) Fumiyuki Soma et al.   Nature Communications

Desensitization of ABA-Signaling: The Swing From Activation to Degradation

(2020) Akhtar Ali et al.   Frontiers in Plant Science

Regulation of ABA-Non-Activated SNF1-Related Protein Kinase 2 Signaling Pathways by Phosphatidic Acid

(2020) Maria Klimecka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Decoding ABA and osmostress signalling in plants from an evolutionary point of view

(2020) Kenji Komatsu et al.   PLANT CELL AND ENVIRONMENT

Signaling mechanisms in abscisic acid‐mediated stomatal closure

(2020) Po‐Kai Hsu et al.   PLANT JOURNAL

Role of Raf-like kinases in SnRK2 activation and osmotic stress response in plants

(2020) Norma Fàbregas et al.   Nature Communications

SNF1-Related Protein Kinases SnRK2.4 and SnRK2.10 Modulate ROS Homeostasis in Plant Response to Salt Stress

(2019) Katarzyna Patrycja Szymańska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Abscisic Acid Signaling in Maintaining the Metabolic Balance Required for Arabidopsis Growth under Non-stress Conditions

(2019) Takuya Yoshida et al.   PLANT CELL

The flip side of phospho‐signaling: regulation of protein dephosphorylation and the protein phosphatase 2Cs

(2019) Govinal Badiger Bhaskar et al.   PLANT CELL AND ENVIRONMENT

PUB25 and PUB26 Promote Plant Freezing Tolerance by Degrading the Cold Signaling Negative Regulator MYB15

(2019) Xi Wang et al.   DEVELOPMENTAL CELL

Rheostatic control of ABA signaling through HOS15-mediated OST1 degradation

(2019) Akhtar Ali et al.   Molecular Plant

SnRK2 protein kinases and mRNA decapping machinery control root development and response to salt

(2019) Dorota Kawa et al.   PLANT PHYSIOLOGY

The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity

(2019) Germanna Lima Righetto et al.   Frontiers in Plant Science

ABA‐triggered guard cell L ‐cysteine desulfhydrase function and in situ H 2 S production contributes to heme oxygenase‐modulated stomatal closure

(2019) Jing Zhang et al.   PLANT CELL AND ENVIRONMENT

Two SnRK2-interacting Calcium Sensor Isoforms Negatively Regulate SnRK2 Activity by Different Mechanisms

(2019) Krzysztof Tarnowski et al.   PLANT PHYSIOLOGY

Model-driven discovery of calcium-related protein-phosphatase inhibition in plant guard cell signaling

(2019) Parul Maheshwari et al.   PLoS Computational Biology

Abscisic acid dynamics, signaling, and functions in plants

(2019) Kong Chen et al.   Journal of Integrative Plant Biology

The Sucrose Non-Fermenting 1-Related Protein Kinase 2 (SnRK2) Genes Are Multifaceted Players in Plant Growth, Development and Response to Environmental Stimuli

(2019) Xinguo Mao et al.   PLANT AND CELL PHYSIOLOGY

The Arabidopsis kinase-associated protein phosphatase KAPP, interacting with protein kinases SnRK2.2/2.3/2.6, negatively regulates abscisic acid signaling

(2019) Kai Lu et al.   PLANT MOLECULAR BIOLOGY

Arabidopsis subtilase SASP is involved in the regulation of ABA signaling and drought tolerance by interacting with OST1

(2018) Qianqian Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Glucose triggers stomatal closure mediated by basal signaling through HXK1 and PYR/RCAR receptors in Arabidopsis

(2018) Yan Li et al.   JOURNAL OF EXPERIMENTAL BOTANY

Reciprocal Regulation of the TOR Kinase and ABA Receptor Balances Plant Growth and Stress Response

(2018) Pengcheng Wang et al.   MOLECULAR CELL

Abscisic Acid Signaling Inhibits Brassinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2

(2018) Haijiao Wang et al.   Molecular Plant

The Antagonistic Action of Abscisic Acid and Cytokinin Signaling Mediates Drought Stress Response in Arabidopsis

(2018) Xiaozhen Huang et al.   Molecular Plant

Mutations in a subfamily of abscisic acid receptor genes promote rice growth and productivity

(2018) Chunbo Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity

(2018) Yang Zhao et al.   Cell Reports

EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis

(2018) Yanglin Ding et al.   EMBO JOURNAL

Fine-tuning of RBOHF activity is achieved by differential phosphorylation and Ca2+ binding

(2018) Jian-Pu Han et al.   NEW PHYTOLOGIST

Phosphoproteomic analysis reveals that dehydrins ERD10 and ERD14 are phosphorylated by SNF1‐related protein kinase 2.10 in response to osmotic stress

(2018) Justyna Maszkowska et al.   PLANT CELL AND ENVIRONMENT

Ethylene-Induced Hydrogen Sulfide Negatively Regulates Ethylene Biosynthesis by Persulfidation of ACO in Tomato Under Osmotic Stress

(2018) Honglei Jia et al.   Frontiers in Plant Science

Reconstitution of Abscisic Acid Signaling from the Receptor to DNA via bHLH Transcription Factors

(2017) Yohei Takahashi et al.   PLANT PHYSIOLOGY

The SnRK2 kinases modulate miRNA accumulation in Arabidopsis

(2017) Jun Yan et al.   PLoS Genetics

SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

(2017) Chunhong Cheng et al.   PLoS Genetics

Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase

(2016) Ewa Krzywińska et al.   BMC PLANT BIOLOGY

The sucrose non-fermenting 1-related kinase 2 gene SAPK9 improves drought tolerance and grain yield in rice by modulating cellular osmotic potential, stomatal closure and stress-responsive gene expression

(2016) Avishek Dey et al.   BMC PLANT BIOLOGY

Hydrogen Sulfide Activates S-Type Anion Channel via OST1 and Ca 2+ Modules

(2016) Lei Wang et al.   Molecular Plant

BRI1-Associated Receptor Kinase 1 Regulates Guard Cell ABA Signaling Mediated by Open Stomata 1 in Arabidopsis

(2016) Yun Shang et al.   Molecular Plant

Type One Protein Phosphatase 1 and Its Regulatory Protein Inhibitor 2 Negatively Regulate ABA Signaling

(2016) Yueh-Ju Hou et al.   PLoS Genetics

OST1 Kinase Modulates Freezing Tolerance by Enhancing ICE1 Stability in Arabidopsis

(2015) Yanglin Ding et al.   DEVELOPMENTAL CELL

Casein Kinase 2 Negatively Regulates Abscisic Acid-Activated SnRK2s in the Core Abscisic Acid-Signaling Module

(2015) Belmiro Vilela et al.   Molecular Plant

Aquaporins Contribute to ABA-Triggered Stomatal Closure through OST1-Mediated Phosphorylation

(2015) Alexandre Grondin et al.   PLANT CELL

Arabidopsis RZFP34/CHYR1, a Ubiquitin E3 Ligase, Regulates Stomatal Movement and Drought Tolerance via SnRK2.6-Mediated Phosphorylation

(2015) Shuangcheng Ding et al.   PLANT CELL

Two Distinct Families of Protein Kinases Are Required for Plant Growth under High External Mg2+Concentrations in Arabidopsis

(2015) Junro Mogami et al.   PLANT PHYSIOLOGY

Plant Raf-like kinase integrates abscisic acid and hyperosmotic stress signaling upstream of SNF1-related protein kinase2

(2015) Masashi Saruhashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SnRK2-APC/CTE regulatory module mediates the antagonistic action of gibberellic acid and abscisic acid pathways

(2015) Qibing Lin et al.   Nature Communications

Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells

(2015) Benjamin Brandt et al.   eLife

Abscisic acid perception and signaling: structural mechanisms and applications

(2014) Ley Moy Ng et al.   ACTA PHARMACOLOGICA SINICA

Identification and functional characterization of theArabidopsis Snf1-related protein kinase SnRK2.4 phosphatidic acid-binding domain

(2014) MAGDALENA M. JULKOWSKA et al.   PLANT CELL AND ENVIRONMENT

Arabidopsis RAV1 transcription factor, phosphorylated by SnRK2 kinases, regulates the expression ofABI3,ABI4, andABI5during seed germination and early seedling development

(2014) Cui-Zhu Feng et al.   PLANT JOURNAL

Hydrogen Sulfide Generated by L-Cysteine Desulfhydrase Acts Upstream of Nitric Oxide to Modulate Abscisic Acid-Dependent Stomatal Closure

(2014) D. Scuffi et al.   PLANT PHYSIOLOGY

H2O2 Inhibits ABA-Signaling Protein Phosphatase HAB1

(2014) Madhuri Sridharamurthy et al.   PLoS One

Abscisic acid sensor RCAR7/PYL13, specific regulator of protein phosphatase coreceptors

(2014) S. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s inArabidopsis

(2014) Zhenying Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric oxide negatively regulates abscisic acid signaling in guard cells by S-nitrosylation of OST1

(2014) Pengcheng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling

(2013) Yang Zhao et al.   CELL RESEARCH

Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13

(2013) Wenqi Li et al.   CELL RESEARCH

Advanced Proteomic Analyses Yield a Deep Catalog of Ubiquitylation Targets inArabidopsis

(2013) Do-Young Kim et al.   PLANT CELL

Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action

(2013) P. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance

(2013) M. Okamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics and Phosphoproteomics Reveal a Protein Phosphorylation Network in the Abscisic Acid Signaling Pathway in Arabidopsis thaliana

(2013) T. Umezawa et al.   Science Signaling

The Snf1-related protein kinases SnRK2.4 and SnRK2.10 are involved in maintenance of root system architecture during salt stress

(2012) Fionn McLoughlin et al.   PLANT JOURNAL

SNF1-Related Protein Kinases Type 2 Are Involved in Plant Responses to Cadmium Stress

(2012) A. Kulik et al.   PLANT PHYSIOLOGY

PYRABACTIN RESISTANCE1-LIKE8 Plays an Important Role for the Regulation of Abscisic Acid Signaling in Root

(2012) R. Antoni et al.   PLANT PHYSIOLOGY

Reconstitution of abscisic acid activation of SLAC1 anion channel by CPK6 and OST1 kinases and branched ABI1 PP2C phosphatase action

(2012) B. Brandt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanism for Inhibition of a Critical Component in theArabidopsis thalianaAbscisic Acid Signal Transduction Pathways, SnRK2.6, by Protein Phosphatase ABI1

(2011) Tian Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence that abscisic acid promotes degradation of SNF1-related protein kinase (SnRK) 1 in wheat and activation of a putative calcium-dependent SnRK2

(2011) P. Coello et al.   JOURNAL OF EXPERIMENTAL BOTANY

The Structure of Arabidopsis thaliana OST1 Provides Insights into the Kinase Regulation Mechanism in Response to Osmotic Stress

(2011) Cristina Yunta et al.   JOURNAL OF MOLECULAR BIOLOGY

The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins

(2011) Qi Hao et al.   MOLECULAR CELL

SnRK2 Protein Kinases—Key Regulators of Plant Response to Abiotic Stresses

(2011) Anna Kulik et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Arabidopsis decuple mutant reveals the importance of SnRK2 kinases in osmotic stress responses in vivo

(2011) H. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases

(2011) L.-M. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases

(2011) F.-F. Soon et al.   SCIENCE

Regulation ofNicotiana tabacumosmotic stress-activated protein kinase and its cellular partner GAPDH by nitric oxide in response to salinity

(2010) Izabela Wawer et al.   BIOCHEMICAL JOURNAL

SNF1-related Protein Kinases 2 Are Negatively Regulated by a Plant-specific Calcium Sensor

(2010) Maria Bucholc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis of the Core Regulatory Network in ABA Responses: Sensing, Signaling and Transport

(2010) T. Umezawa et al.   PLANT AND CELL PHYSIOLOGY

Two Closely Related Subclass II SnRK2 Protein Kinases Cooperatively Regulate Drought-Inducible Gene Expression

(2010) Masahide Mizoguchi et al.   PLANT AND CELL PHYSIOLOGY

Phospho-site mapping, genetic and in planta activation studies reveal key aspects of the different phosphorylation mechanisms involved in activation of SnRK2s

(2010) Florina Vlad et al.   PLANT JOURNAL

In vitro reconstitution of an abscisic acid signalling pathway

(2009) Hiroaki Fujii et al.   NATURE

Structural basis of abscisic acid signalling

(2009) Ken-ichi Miyazono et al.   NATURE

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors

(2009) Karsten Melcher et al.   NATURE

Structural insights into the mechanism of abscisic acid signaling by PYL proteins

(2009) Ping Yin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The CBL-CIPK Ca2+-decoding signaling network: function and perspectives

(2009) Stefan Weinl et al.   NEW PHYTOLOGIST

Three Arabidopsis SnRK2 Protein Kinases, SRK2D/SnRK2.2, SRK2E/SnRK2.6/OST1 and SRK2I/SnRK2.3, Involved in ABA Signaling are Essential for the Control of Seed Development and Dormancy

(2009) Kazuo Nakashima et al.   PLANT AND CELL PHYSIOLOGY

Protein Phosphatases 2C Regulate the Activation of the Snf1-Related Kinase OST1 by Abscisic Acid in Arabidopsis

(2009) F. Vlad et al.   PLANT CELL

Enhanced Abscisic Acid-Mediated Responses in nia1nia2noa1-2 Triple Mutant Impaired in NIA/NR- and AtNOA1-Dependent Nitric Oxide Biosynthesis in Arabidopsis

(2009) J. Lozano-Juste et al.   PLANT PHYSIOLOGY

Arabidopsis mutant deficient in 3 abscisic acid-activated protein kinases reveals critical roles in growth, reproduction, and stress

(2009) H. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis

(2009) T. Umezawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair

(2009) Dietmar Geiger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A protein kinase-phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells

(2009) Sung Chul Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors

(2009) Y. Ma et al.   SCIENCE

Differential requirement for NO during ABA-induced stomatal closure in turgid and wilted leaves

(2008) DIMAS M. RIBEIRO et al.   PLANT CELL AND ENVIRONMENT