A Novel Screen for Expression Regulators of the Telomeric Protein TRF2 Identified Small Molecules That Impair TRF2 Dependent Immunosuppression and Tumor Growth

The fluorescent protein stability assay: an efficient method for monitoring intracellular protein stability

(2021) Armelle Roisin et al.   BIOTECHNIQUES

Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime

(2020) Jérôme D. Robin et al.   AGING CELL

Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential

(2020) Stina George Fernandes et al.   Cancers

TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment

(2019) Pasquale Zizza et al.   NUCLEIC ACIDS RESEARCH

Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2

(2019) Julien Cherfils‐Vicini et al.   EMBO JOURNAL

In perspective: An update on telomere targeting in cancer

(2019) Eric T. Sugarman et al.   MOLECULAR CARCINOGENESIS

Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells

(2019) Julien Cherfils‐Vicini et al.   EMBO Molecular Medicine

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress

(2018) R. Garrett Morgan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinoma

(2016) Yordan Benhamou et al.   Oncotarget

The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?

(2016) Vasileios Kordinas et al.   Genes

Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability

(2015) Martin Bennett et al.   CIRCULATION

Telomere dysfunction causes alveolar stem cell failure

(2015) Jonathan K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

(2015) Hilary A. Kenny et al.   Nature Communications

Shading the TRF2 Recruiting Function: A New Horizon in Drug Development

(2014) Salvatore Di Maro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Telomeric Protein TRF2 Regulates Angiogenesis by Binding and Activating the PDGFRβ Promoter

(2014) Mounir El Maï et al.   Cell Reports

A novel pathway links telomeres to NK-cell activity

(2014) Julien Cherfils-Vicini et al.   OncoImmunology

Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway

(2013) Irmina Diala et al.   EMBO REPORTS

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

(2013) Annamaria Biroccio et al.   NATURE CELL BIOLOGY

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia

(2013) Andrew J Ramsay et al.   NATURE GENETICS

One Identity or More for Telomeres?

(2013) Marie-Josèphe Giraud-Panis et al.   Frontiers in Oncology

Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer

(2012) Jian Hu et al.   CELL

Gemcitabine causes telomere attrition by stabilizing TRF2

(2012) Chih-Hao Su et al.   EUROPEAN JOURNAL OF CANCER

The telomere syndromes

(2012) Mary Armanios et al.   NATURE REVIEWS GENETICS

Telomeric damage in early stage of chronic lymphocytic leukemia correlates with shelterin dysregulation

(2011) A. Augereau et al.   BLOOD

Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence

(2010) Kaori Fujita et al.   NATURE CELL BIOLOGY

Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer

(2008) Samanthi A. Perera et al.   CARCINOGENESIS