The Extracellular Metabolome Stratifies Low and High Risk Potentially Premalignant Oral Keratinocytes and Identifies Citrate as a Potential Non-Invasive Marker of Tumour Progression

The role of icIL-1RA in keratinocyte senescence and development of the senescence-associated secretory phenotype

(2021) Sven E. Niklander et al.   JOURNAL OF CELL SCIENCE

Cancer-associated cells release citrate to support tumour metastatic progression

(2021) Konstantin Drexler et al.   Life Science Alliance

Assessing aneuploidy with repetitive element sequencing

(2020) Christopher Douville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A proteomic atlas of senescence-associated secretomes for aging biomarker development

(2020) Nathan Basisty et al.   PLOS BIOLOGY

Cellular senescence promotes skin carcinogenesis through p38MAPK and p44/p42MAPK signaling

(2020) Fatouma Alimirah et al.   CANCER RESEARCH

Oral squamous cell carcinoma diagnosed from saliva metabolic profiling

(2020) Xiaowei Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ROCK inhibition modulates the senescence‐associated secretory phenotype (SASP) in oral keratinocytes

(2020) Sven Niklander et al.   FEBS Open Bio

Extracellular Citrate Fuels Cancer Cell Metabolism and Growth

(2020) Sebastian Haferkamp et al.   Frontiers in Cell and Developmental Biology

Potential Use of Gluconate in Cancer Therapy

(2019) Maria E. Mycielska et al.   Frontiers in Oncology

Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy

(2019) Ratna Veeramachaneni et al.   Scientific Reports

Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer DevelopmentIn Vivo

(2018) Maria E. Mycielska et al.   CANCER RESEARCH

Inflammatory Bacteriome and Oral Squamous Cell Carcinoma

(2018) M. Perera et al.   JOURNAL OF DENTAL RESEARCH

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

Extracellular Citrate and Cancer Metabolism—Response

(2018) Maria E. Mycielska et al.   CANCER RESEARCH

Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal Lining

(2018) D. Vicky de Boer et al.   MOLECULAR CANCER RESEARCH

The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples

(2017) Henry M. Wood et al.   Genome Medicine

Fibroblast activation and senescence in oral cancer

(2016) S. S. Prime et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism

(2016) Emma L. James et al.   Scientific Reports

Oral Microbiome Metabolism

(2015) N. Takahashi   JOURNAL OF DENTAL RESEARCH

Senescent Human Fibroblasts Show Increased Glycolysis and Redox Homeostasis with Extracellular Metabolomes That Overlap with Those of Irreparable DNA Damage, Aging, and Disease

(2015) Emma L. James et al.   JOURNAL OF PROTEOME RESEARCH

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells

(2015) Michael C. Velarde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics

(2015) Stefano Tiziani et al.   NEOPLASIA

Targeted Deletion and Lipidomic Analysis Identify Epithelial Cell COX-2 as a Major Driver of Chemically Induced Skin Cancer

(2014) Jing Jiao et al.   MOLECULAR CANCER RESEARCH

Changes in Abundance of Oral Microbiota Associated with Oral Cancer

(2014) Brian L. Schmidt et al.   PLoS One

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

(2014) E. C. de Bruin et al.   SCIENCE

Regulatory T cell subsets in human cancer: are they regulating for or against tumor progression?

(2013) Theresa L. Whiteside   CANCER IMMUNOLOGY IMMUNOTHERAPY

Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β

(2013) Yazan Hassona et al.   CARCINOGENESIS

Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model

(2013) Christin E. Burd et al.   CELL

Prostaglandin and the Suppression of Phagocyte Innate Immune Responses in Different Organs

(2012) Alexandra Medeiros et al.   MEDIATORS OF INFLAMMATION

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Salivary metabolite signatures of oral cancer and leukoplakia

(2010) Jie Wei et al.   INTERNATIONAL JOURNAL OF CANCER

Methylation of p16 CpG Island Associated with Malignant Progression of Oral Epithelial Dysplasia: A Prospective Cohort Study

(2009) J. Cao et al.   CLINICAL CANCER RESEARCH

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

(2009) Masahiro Sugimoto et al.   Metabolomics

DNA ploidy analysis by image cytometry helps to identify oral epithelial dysplasias with a high risk of malignant progression

(2008) A. Torres-Rendon et al.   ORAL ONCOLOGY