Local IP3 receptor–mediated Ca2+ signals compound to direct blood flow in brain capillaries

Brain capillary pericytes exert a substantial but slow influence on blood flow

(2021) David A. Hartmann et al.   NATURE NEUROSCIENCE

Brain endothelial cell TRPA1 channels initiate neurovascular coupling

(2021) Pratish Thakore et al.   eLife

Precapillary sphincters maintain perfusion in the cerebral cortex

(2020) Søren Grubb et al.   Nature Communications

Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage

(2020) Julien Ratelade et al.   CIRCULATION

Contractile pericytes determine the direction of blood flow at capillary junctions

(2020) Albert L. Gonzales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

(2019) Jaime Grutzendler et al.   TRENDS IN NEUROSCIENCES

Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia

(2018) Ravi L. Rungta et al.   NEURON

Activity-induced Ca2+ signaling in perisynaptic Schwann cells of the early postnatal mouse is mediated by P2Y1 receptors and regulates muscle fatigue

(2018) Dante J Heredia et al.   eLife

PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

(2018) Osama F Harraz et al.   eLife

Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex

(2017) Roger I Grant et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clustering of Ca 2+ transients in interstitial cells of Cajal defines slow wave duration

(2017) Bernard T. Drumm et al.   JOURNAL OF GENERAL PHYSIOLOGY

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

(2017) Thomas A Longden et al.   NATURE NEUROSCIENCE

The capillary bed offers the largest hemodynamic resistance to the cortical blood supply

(2016) Ian Gopal Gould et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease

(2016) Michael J. Berridge   PHYSIOLOGICAL REVIEWS

COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex

(2015) A. Lacroix et al.   JOURNAL OF NEUROSCIENCE

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

(2015) Robert A. Hill et al.   NEURON

The experimental power of FR900359 to study Gq-regulated biological processes

(2015) Ramona Schrage et al.   Nature Communications

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function

(2014) T. A. Longden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding dynamic Ca2+ signaling in the vascular endothelium

(2014) Mark S. Taylor et al.   Frontiers in Physiology

An artery-specific fluorescent dye for studying neurovascular coupling

(2012) Zhiming Shen et al.   NATURE METHODS

The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit

(2012) Andy Y Shih et al.   NATURE NEUROSCIENCE

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Calcium Signaling in Smooth Muscle

(2011) D. C. Hill-Eubanks et al.   Cold Spring Harbor Perspectives in Biology

Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells

(2009) I. F. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concepts of neural nitric oxide-mediated transmission

(2008) John Garthwaite   EUROPEAN JOURNAL OF NEUROSCIENCE

Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections

(2008) J. Ledoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA