Single-cell analyses unravel cell type–specific responses to a vitamin D analog in prostatic precancerous lesions

Cancer statistics, 2020

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Vitamin D receptor agonist paricalcitol plus gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer.

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New aspects of vitamin D metabolism and action — addressing the skin as source and target

(2020) Daniel Bikle et al.   Nature Reviews Endocrinology

Regenerative potential of prostate luminal cells revealed by single-cell analysis

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NF-κB signaling promotes castration-resistant prostate cancer initiation and progression

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Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips

(2020) Wangxin Guo et al.   NATURE GENETICS

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

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Vitamin D Signaling Suppresses Early Prostate Carcinogenesis in TgAPT121 Mice

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Comprehensive Integration of Single-Cell Data

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Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor

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1α, 25 Dihydroxyvitamin D (1,25(OH)2D) inhibits the T cell suppressive function of myeloid derived suppressor cells (MDSC)

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The invasin D protein fromYersinia pseudotuberculosisselectively binds the Fab region of host antibodies and affects colonization of the intestine

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PTENdeletion in luminal cells of mature prostate induces replication stress and senescence in vivo

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IL-23 secreted by myeloid cells drives castration-resistant prostate cancer

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Senescence and senotherapeutics: a new field in cancer therapy

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Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

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A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours

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Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells

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Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

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Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer

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Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

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Early Growth Inhibition Is Followed by Increased Metastatic Disease with Vitamin D (Calcitriol) Treatment in the TRAMP Model of Prostate Cancer

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Vitamin D Receptor in Osteoblasts Is a Negative Regulator of Bone Mass Control

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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

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The NF- B Family of Transcription Factors and Its Regulation

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Gemini Vitamin D Analogues Inhibit Estrogen Receptor-Positive and Estrogen Receptor-Negative Mammary Tumorigenesis without Hypercalcemic Toxicity

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Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma

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