Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia

Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner

(2021) Cheng Zhang et al.   Cell Death & Disease

Proteasome in action: substrate degradation by the 26S proteasome

(2021) Indrajit Sahu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Bnip3 in mitophagy: novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction

(2020) Anbo Gao et al.   CLINICA CHIMICA ACTA

Redox homeostasis, oxidative stress and mitophagy

(2020) Carla Garza-Lombó et al.   MITOCHONDRION

Dynamic Regulation of Mitochondrial Import by the Ubiquitin System

(2020) Lilian Phu et al.   MOLECULAR CELL

BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains

(2020) Xiaoli Wu et al.   Autophagy

Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

(2020) Pin-Chao Liao et al.   Cell Reports

Inhibition of proteasome reveals basal mitochondrial ubiquitination

(2020) Prasad Sulkshane et al.   Journal of Proteomics

Ubiquitination of Intramitochondrial Proteins: Implications for Metabolic Adaptability

(2020) Prasad Sulkshane et al.   Biomolecules

FKBP8 LIRL‐dependent mitochondrial fragmentation facilitates mitophagy under stress conditions

(2019) Seung‐Min Yoo et al.   FASEB JOURNAL

CoCl2 induces apoptosis via ROS-dependent pathway and Drp1-mediated mitochondria fission in the periodontal ligament stem cells

(2018) Yuting He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Building and decoding ubiquitin chains for mitophagy

(2018) J. Wade Harper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMBRA1-Mediated Mitophagy Counteracts Oxidative Stress and Apoptosis Induced by Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells

(2018) Anthea Di Rita et al.   Frontiers in Cellular Neuroscience

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

(2018) Anthea Di Rita et al.   Nature Communications

Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid

(2018) Omar Emiliano Aparicio-Trejo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The use of cobalt chloride as a chemical hypoxia model

(2018) Jorge Muñoz-Sánchez et al.   JOURNAL OF APPLIED TOXICOLOGY

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

The role of declining adaptive homeostasis in ageing

(2017) Laura C. D. Pomatto et al.   JOURNAL OF PHYSIOLOGY-LONDON

HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation

(2015) Hak-June Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis

(2015) A. H. Chourasia et al.   EMBO REPORTS

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

(2015) Alban Ordureau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The demographics of the ubiquitin system

(2015) Michael J. Clague et al.   TRENDS IN CELL BIOLOGY

A novel link between autophagy and the ubiquitin-proteasome system

(2014) Viktor I. Korolchuk et al.   Autophagy

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

(2014) Agne Kazlauskaite et al.   BIOCHEMICAL JOURNAL

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Reversible 26S Proteasome Disassembly upon Mitochondrial Stress

(2014) Nurit Livnat-Levanon et al.   Cell Reports

NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity

(2013) Ying-Na Li et al.   TOXICOLOGY LETTERS

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

(2012) Magdalena Frank et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis

(2012) Guillaume P. Leboucher et al.   MOLECULAR CELL

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

(2011) Shengnan Wu et al.   FEBS Journal

Ubiquitin-dependent mitochondrial protein degradation

(2011) Jin-Mi Heo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

N-acetyl Cysteine Treatment Rescues Cognitive Deficits Induced by Mitochondrial Dysfunction in G72/G30 Transgenic Mice

(2011) David-Marian Otte et al.   NEUROPSYCHOPHARMACOLOGY

Quality Control of Mitochondrial Proteostasis

(2011) M. J. Baker et al.   Cold Spring Harbor Perspectives in Biology

Hypoxia and mitochondrial oxidative metabolism

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ubiquitin–Proteasome System and mitochondria — Reciprocity

(2010) Nurit Livnat-Levanon et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Stressed-Out Mitochondria Get MAD

(2010) Marc Chatenay-Lapointe et al.   Cell Metabolism

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

(2010) Shan Xu et al.   MOLECULAR BIOLOGY OF THE CELL

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

(2009) Elsa Lauwers et al.   JOURNAL OF CELL BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL