Pharmacological inhibition of sodium-calcium exchange activates NADPH oxidase and induces infection-independent NETotic cell death

The burden of chronic diseases among Australian cancer patients: Evidence from a longitudinal exploration, 2007-2017

(2020) Rashidul Alam Mahumud et al.   PLoS One

Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis

(2018) Minoru Inoue et al.   Nature Communications

Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress

(2016) Samer Tohme et al.   CANCER RESEARCH

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand

(2015) Samuel DeLuca et al.   PLoS One

Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide

(2015) Ross Corriden et al.   Nature Communications

BCL::Conf: small molecule conformational sampling using a knowledge based rotamer library

(2015) Sandeepkumar Kothiwale et al.   Journal of Cheminformatics

NET formation induced by Pseudomonas aeruginosa cystic fibrosis isolates measured as release of myeloperoxidase–DNA and neutrophil elastase–DNA complexes

(2014) Dae-goon Yoo et al.   IMMUNOLOGY LETTERS

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

(2014) Anurag Kumar Gupta et al.   PLoS One

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Small-molecule ligand docking into comparative models with Rosetta

(2013) Steven A Combs et al.   Nature Protocols

Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

(2013) Sergey Lyskov et al.   PLoS One

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Cancer Cells

(2011) Jan-Gowth Chang et al.   PLoS One

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Intercellular Adhesion Molecule-1–Dependent Neutrophil Adhesion to Endothelial Cells Induces Caveolae-Mediated Pulmonary Vascular Hyperpermeability

(2008) Guochang Hu et al.   CIRCULATION RESEARCH