SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells
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Title
SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-06-09
DOI
10.3389/fimmu.2021.679482
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Note: Only part of the references are listed.- Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia
- (2021) Rogan A. Grant et al. NATURE
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Pathogenesis of COVID-19 from a cell biology perspective
- (2020) Robert J. Mason EUROPEAN RESPIRATORY JOURNAL
- Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study
- (2020) Barnaby E Young et al. LANCET
- ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection
- (2020) Asmaa Hachim et al. NATURE IMMUNOLOGY
- SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
- (2020) Lisa Miorin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway
- (2020) Jin-Yan Li et al. VIRUS RESEARCH
- Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein
- (2020) Xiaohui Wang et al. mBio
- Expression of SARS-CoV-2 entry factors in lung epithelial stem cells and its potential implications for COVID-19
- (2020) Anna A. Valyaeva et al. Scientific Reports
- SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence
- (2020) Sameer Mohammad et al. Pathogens
- Stimulation of Innate Immunity by Host and Viral RNAs
- (2019) Felix Streicher et al. TRENDS IN IMMUNOLOGY
- In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration
- (2018) Hua Geng et al. GASTROENTEROLOGY
- ZBP1: Innate Sensor Regulating Cell Death and Inflammation
- (2018) Teneema Kuriakose et al. TRENDS IN IMMUNOLOGY
- Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3
- (2018) Hui Hui Wong et al. VIROLOGY
- A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation
- (2018) Antonio Gregorio Dias Junior et al. TRENDS IN MICROBIOLOGY
- SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death
- (2018) Yuan Yue et al. Cell Death & Disease
- Protein aggregation and ER stress
- (2016) Navit Ogen-Shtern et al. BRAIN RESEARCH
- Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses
- (2016) Yize Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation
- (2016) Joshua M. Thornbrough et al. mBio
- Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets
- (2015) Yang Yang et al. Scientific Reports
- DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation
- (2015) Hiroyuki Oshiumi et al. Cell Reports
- MDA5 and LGP2: Accomplices and Antagonists of Antiviral Signal Transduction
- (2014) K. R. Rodriguez et al. JOURNAL OF VIROLOGY
- The 2'-5'-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2'-5'-Oligoadenylates Required for RNase L Activation
- (2014) M. S. Ibsen et al. JOURNAL OF VIROLOGY
- Host and Viral Determinants of Mx2 Antiretroviral Activity
- (2014) Idoia Busnadiego et al. JOURNAL OF VIROLOGY
- The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly
- (2014) Annie M. Bruns et al. MOLECULAR CELL
- PASTA 2.0: an improved server for protein aggregation prediction
- (2014) Ian Walsh et al. NUCLEIC ACIDS RESEARCH
- Interferon induction of IFITM proteins promotes infection by human coronavirus OC43
- (2014) X. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IFITM-Family Proteins: The Cell's First Line of Antiviral Defense
- (2014) Charles C. Bailey et al. Annual Review of Virology
- Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk
- (2013) Romulus Breban et al. LANCET
- Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited
- (2013) J. Verhelst et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- MX2 is an interferon-induced inhibitor of HIV-1 infection
- (2013) Melissa Kane et al. NATURE
- The Role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis
- (2012) Ruth McBride et al. Viruses-Basel
- Virus-Induced Aggregates in Infected Cells
- (2012) Adi Moshe et al. Viruses-Basel
- DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling
- (2011) M. Miyashita et al. MOLECULAR AND CELLULAR BIOLOGY
- Dynamin-like MxA GTPase: Structural Insights into Oligomerization and Implications for Antiviral Activity
- (2010) Otto Haller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LGP2: Positive about viral sensing
- (2010) E. M. Y. Moresco et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
- (2010) T. Satoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The SARS Coronavirus 3a Protein Causes Endoplasmic Reticulum Stress and Induces Ligand-Independent Downregulation of the Type 1 Interferon Receptor
- (2009) Rinki Minakshi et al. PLoS One
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