How Children Are Protected From COVID-19? A Historical, Clinical, and Pathophysiological Approach to Address COVID-19 Susceptibility

Causes of death and comorbidities in hospitalized patients with COVID-19

(2021) Sefer Elezkurtaj et al.   Scientific Reports

Post-rituximab immunoglobulin M (IgM) hypogammaglobulinemia

(2020) Khalaf Kridin et al.   AUTOIMMUNITY REVIEWS

A Well Infant with Coronavirus Disease 2019 (COVID-19) with High Viral Load

(2020) Kai-qian Kam et al.   CLINICAL INFECTIOUS DISEASES

Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics

(2020) David Gurwitz   DRUG DEVELOPMENT RESEARCH

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

(2020) Yingxia Liu et al.   Science China-Life Sciences

Respiratory support for patients with COVID-19 infection

(2020) Silvio A Ñamendys-Silva   Lancet Respiratory Medicine

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

Clinical course of COVID-19 in a series of patients with chronic arthritis treated with immunosuppressive targeted therapies

(2020) Sara Monti et al.   ANNALS OF THE RHEUMATIC DISEASES

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

(2020) Ennio Giulio Favalli et al.   AUTOIMMUNITY REVIEWS

Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis

(2020) Brandon Michael Henry et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Will children reveal their secret? The coronavirus dilemma

(2020) Luca Cristiani et al.   EUROPEAN RESPIRATORY JOURNAL

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia

(2020) Hui Zeng et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn

(2020) Lan Dong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A possible role for B cells in COVID-19? Lesson from patients with agammaglobulinemia

(2020) Isabella Quinti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hyperinflammatory shock in children during COVID-19 pandemic

(2020) Shelley Riphagen et al.   LANCET

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

(2020) Lucio Verdoni et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Baricitinib for COVID-19: a suitable treatment? – Authors' reply

(2020) Peter J Richardson et al.   LANCET INFECTIOUS DISEASES

SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine “storm” and risk factor for damage of hematopoietic stem cells

(2020) Mariusz Z. Ratajczak et al.   LEUKEMIA

Drivers and regulators of humoral innate immune responses to infection and cancer

(2020) Deepak Kumar et al.   MOLECULAR IMMUNOLOGY

Children with Covid-19 in Pediatric Emergency Departments in Italy

(2020) Niccolò Parri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

(2020) Muthiah Vaduganathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Infection in Children

(2020) Xiaoxia Lu et al.   NEW ENGLAND JOURNAL OF MEDICINE

On the Alert for Cytokine Storm: Immunopathology in COVID ‐19

(2020) Lauren A. Henderson et al.   Arthritis & Rheumatology

Is SARS-CoV-2 Vertically Transmitted?

(2020) Ana Cristina Simões e Silva et al.   Frontiers in Pediatrics

Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation

(2020) Jiawei Chen et al.   AGING CELL

Understanding the age divide in COVID-19: why are children overwhelmingly spared?

(2020) K. Lingappan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased risk for severe COVID-19 in patients with inflammatory rheumatic diseases treated with rituximab

(2020) Hendrik Schulze-Koops et al.   ANNALS OF THE RHEUMATIC DISEASES

Treatment of patients with inflammatory rheumatic diseases with rituximab should be carefully considered during the SARS-CoV-2/COVID-19 pandemic. Response to: ‘Persistence of rT-PCR-SARS-CoV-2 infection and delayed serological response, as a possible effect of rituximab according to the hypothesis of Schulze-Koops et al’ by Benucci et al

(2020) Hendrik Schulze-Koops et al.   ANNALS OF THE RHEUMATIC DISEASES

Persisting SARS‐CoV‐2 viraemia after rituximab therapy: two cases with fatal outcome and a review of the literature

(2020) Phil‐Robin Tepasse et al.   BRITISH JOURNAL OF HAEMATOLOGY

Thrombosis and COVID-19 pneumonia: the clot thickens!

(2020) Laura C. Price et al.   EUROPEAN RESPIRATORY JOURNAL

Distinct Early Serological Signatures Track with SARS-CoV-2 Survival

(2020) Caroline Atyeo et al.   IMMUNITY

Mild versus severe COVID-19: Laboratory markers

(2020) Thirumalaisamy P. Velavan et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

(2020) Eva W. Cheung et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

COVID-19: Melatonin as a potential adjuvant treatment

(2020) Rui Zhang et al.   LIFE SCIENCES

Factors associated with COVID-19-related death using OpenSAFELY

(2020) Elizabeth J. Williamson et al.   NATURE

COVID-19 in Children, Pregnancy and Neonates

(2020) Petra Zimmermann et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

BCG vaccine protection from severe coronavirus disease 2019 (COVID-19)

(2020) Luis E. Escobar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimation of COVID-19 prevalence in Italy, Spain, and France

(2020) Zeynep Ceylan   SCIENCE OF THE TOTAL ENVIRONMENT

Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities

(2020) Puja Mehta et al.   Lancet Respiratory Medicine

Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study

(2020) Danying Liao et al.   Lancet Haematology

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

(2020) Conor N. Gruber et al.   CELL

National Trends of Cases of COVID-19 in Children Based on US State Health Department Data

(2020) Blake Sisk et al.   PEDIATRICS

Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults

(2020) Russell M. Viner et al.   JAMA Pediatrics

Mimicking Behcet's disease: GM‐CSF gain of function mutation in a family suffering from a Behcet's disease‐like disorder marked by extreme pathergy

(2020) Berenice Rösler et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Distinct disease severity between children and older adults with COVID-19: Impacts of ACE2 expression, distribution, and lung progenitor cells

(2020) Zhao Zhang et al.   CLINICAL INFECTIOUS DISEASES

Coronavirus envelope protein: current knowledge

(2019) Dewald Schoeman et al.   Virology Journal

Glycan Reactive Natural Antibodies and Viral Immunity

(2019) J. Stewart New et al.   VIRAL IMMUNOLOGY

Duox2-induced innate immune responses in the respiratory epithelium and intranasal delivery of Duox2 DNA using polymer that mediates immunization

(2018) Yung Jin Jeon et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

B1a B cells require autophagy for metabolic homeostasis and self-renewal

(2018) Alexander J. Clarke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

(2018) Sarah H. Alfaraj et al.   Frontiers of Medicine

Sex-hormone-driven innate antibodies protect females and infants against EPEC infection

(2018) Zhutian Zeng et al.   NATURE IMMUNOLOGY

Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease

(2018) Hseng-Long Yeh et al.   Biomed Research International

Human newborn B cells mount an interferon-α/β receptor-dependent humoral response to respiratory syncytial virus

(2017) Jop Jans et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Defining Natural Antibodies

(2017) Nichol E. Holodick et al.   Frontiers in Immunology

Behcet’s disease: epidemiology, clinical manifestations, and diagnosis

(2016) Fereydoun Davatchi et al.   Expert Review of Clinical Immunology

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease

(2014) Caroline Grönwall et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Coronavirus infection, ER stress, apoptosis and innate immunity

(2014) To S. Fung et al.   Frontiers in Microbiology

NADPH Oxidases in Lung Health and Disease

(2013) Karen Bernard et al.   ANTIOXIDANTS & REDOX SIGNALING

Natural antibodies of newborns recognize oxidative stress-related malondialdehyde acetaldehyde adducts on apoptotic cells and atherosclerotic plaques

(2013) Chunguang Wang et al.   INTERNATIONAL IMMUNOLOGY

A small jab – a big effect: nonspecific immunomodulation by vaccines

(2013) Christine S. Benn et al.   TRENDS IN IMMUNOLOGY

Taurine and inflammatory diseases

(2012) Janusz Marcinkiewicz et al.   AMINO ACIDS

Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63

(2012) R. Dijkman et al.   JOURNAL OF GENERAL VIROLOGY

History of Antibiotics. From Salvarsan to Cephalosporins

(2012) Lorenzo Zaffiri et al.   JOURNAL OF INVESTIGATIVE SURGERY

Pneumococcal vaccination may induce anti-oxidized low-density lipoprotein antibodies that have potentially protective effects against cardiovascular disease

(2012) B. Suthers et al.   VACCINE

Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology

(2010) Jody D. Berry et al.   mAbs

Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

(2010) Anton Soucy-Faulkner et al.   PLoS Pathogens

Three common polymorphisms in theCYBAgene form a haplotype associated with decreased ROS generation

(2009) Karen Bedard et al.   HUMAN MUTATION

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

(2009) Meng-Yun Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

(2007) Albert van der Vliet   FREE RADICAL BIOLOGY AND MEDICINE