Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immune Response in a Mouse Model

A pneumonia outbreak associated with a new coronavirus of probable bat origin

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Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

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Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

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Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

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From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development

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The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement

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Structural basis of receptor recognition by SARS-CoV-2

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Immunogenicity of a DNA vaccine candidate for COVID-19

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The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control

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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

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A Thermostable mRNA Vaccine against COVID-19

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Distinct Early Serological Signatures Track with SARS-CoV-2 Survival

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Identification of an anti-SARS-CoV-2 receptor binding domain directed human monoclonal antibody from a naïve semi-synthetic library

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A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

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SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

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Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions

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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2

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Distinct conformational states of SARS-CoV-2 spike protein

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Severe Acute Respiratory Syndrome Coronavirus 2: From Gene Structure to Pathogenic Mechanisms and Potential Therapy

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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

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SARS-CoV-2 vaccines in development

(2020) Florian Krammer   NATURE

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

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Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

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Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition

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Design and characterization of a germ-line targeting soluble, native-like, trimeric HIV-1 Env lacking key glycans from the V1V2-loop

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T Cell Memory: Understanding COVID-19

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T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

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Structural and functional comparison of SARS-CoV-2-spike receptor binding domain produced in Pichia pastoris and mammalian cells

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Nglyc: A random forest method for prediction of N-Glycosylation sites in eukaryotic protein sequence

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Envelope proteins of two HIV-1 clades induced different epitope-specific antibody response

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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

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The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256

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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8 + T-cell responses: The immunological consequences of the biodistribution profile

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Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules

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Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

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Deciphering key features in protein structures with the new ENDscript server

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Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

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Mechanism of Immunopotentiation and Safety of Aluminum Adjuvants

(2013) Harm HogenEsch   Frontiers in Immunology

Mechanisms of Action of Adjuvants

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Understanding the T cell immune response in SARS coronavirus infection

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Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain

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