Elevated Interleukin-10 Levels in COVID-19: Potentiation of Pro-Inflammatory Responses or Impaired Anti-Inflammatory Action?

Diabetes, obesity, metabolism and SARS-CoV-2 infection: The end of the beginning

(2021) Daniel J. Drucker   Cell Metabolism

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

(2021) Simon Gebremeskel et al.   Frontiers in Immunology

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes

(2020) Lihua Zhu et al.   Cell Metabolism

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

(2020) Ana Campos Codo et al.   Cell Metabolism

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

(2020) Yujun Tang et al.   Frontiers in Immunology

Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease

(2020) Yan Zhao et al.   JCI Insight

The laboratory tests and host immunity of COVID-19 patients with different severity of illness

(2020) Feng Wang et al.   JCI Insight

Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes

(2020) Thomas C. Chamberlain et al.   iScience

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

(2020) Prabhu S. Arunachalam et al.   SCIENCE

A Potential Role of Interleukin 10 in COVID-19 Pathogenesis

(2020) Ligong Lu et al.   TRENDS IN IMMUNOLOGY

Biology and therapeutic potential of interleukin-10

(2019) Margarida Saraiva et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity

(2018) Marko Šestan et al.   IMMUNITY

High glucose induces a priming effect in macrophages and exacerbates the production of pro-inflammatory cytokines after a challenge

(2018) Rachel Grosick et al.   Journal of Pain Research

PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients

(2018) Aung Naing et al.   CANCER CELL

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors

(2016) Aung Naing et al.   JOURNAL OF CLINICAL ONCOLOGY

IL-10 Enhances IgE-Mediated Mast Cell Responses and Is Essential for the Development of Experimental Food Allergy in IL-10–Deficient Mice

(2016) Stephanie H. Polukort et al.   JOURNAL OF IMMUNOLOGY

Hyporesponsiveness to the anti-inflammatory action of interleukin-10 in type 2 diabetes

(2016) Julianne C. Barry et al.   Scientific Reports

NK cells link obesity-induced adipose stress to inflammation and insulin resistance

(2015) Felix M Wensveen et al.   NATURE IMMUNOLOGY

IL-10: Master Switch from Tumor-Promoting Inflammation to Antitumor Immunity

(2014) M. Oft   Cancer Immunology Research

Interleukin-10 Inhibits Lipopolysaccharide-induced Tumor Necrosis Factor-α Translation through a SHIP1-dependent Pathway

(2012) Catherine S. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY