PARK7 Protects Against Chronic Kidney Injury and Renal Fibrosis by Inducing SOD2 to Reduce Oxidative Stress

DJ-1 protects retinal pericytes against high glucose-induced oxidative stress through the Nrf2 signaling pathway

(2020) Wanpeng Wang et al.   Scientific Reports

Autophagy in kidney homeostasis and disease

(2020) Chengyuan Tang et al.   Nature Reviews Nephrology

Role of DJ-1 in Immune and Inflammatory Diseases

(2020) Lulu Zhang et al.   Frontiers in Immunology

ND-13, a DJ-1-Derived Peptide, Attenuates the Renal Expression of Fibrotic and Inflammatory Markers Associated with Unilateral Ureter Obstruction

(2020) Carmen De Miguel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chronic Kidney Disease as Oxidative Stress- and Inflammatory-Mediated Cardiovascular Disease

(2020) Alina Podkowińska et al.   Antioxidants

Mitochondrial quality control in kidney injury and repair

(2020) Chengyuan Tang et al.   Nature Reviews Nephrology

Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury

(2020) Hajera Amatullah et al.   Redox Biology

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation

(2019) Meiling Zheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The protective effect of glutaredoxin 1/DJ-1/HSP70 signaling in renal tubular epithelial cells injury induced by ischemia

(2019) Jian Yin et al.   LIFE SCIENCES

The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression

(2019) Juan Cai et al.   KIDNEY INTERNATIONAL

Reading, writing and erasing mRNA methylation

(2019) Sara Zaccara et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

(2019) Chengyuan Tang et al.   Cell Death & Disease

Functional potato bioactive peptide intensifies Nrf2-dependent antioxidant defense against renal damage in hypertensive rats

(2019) Bruce Chi-Kang Tsai et al.   FOOD RESEARCH INTERNATIONAL

Mechanisms of Renal Fibrosis

(2018) Benjamin D. Humphreys   Annual Review of Physiology

PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury

(2018) Chengyuan Tang et al.   Autophagy

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

DJ-1 based peptide, ND-13, promote functional recovery in mouse model of focal ischemic injury

(2018) Lior Molcho et al.   PLoS One

PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury

(2018) Ying Wang et al.   Cell Death & Disease

Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease

(2018) Shaoqun Shu et al.   EBioMedicine

Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease

(2017) Alice Biosa et al.   NEUROBIOLOGY OF DISEASE

Mechanism of myocardial ischemia/reperfusion‑induced acute kidney injury through DJ‑1/Nrf2 pathway in diabetic rats

(2017) Qian Sun et al.   Experimental and Therapeutic Medicine

DJ-1 Modulates Nuclear Erythroid 2–Related Factor-2–Mediated Protection in Human Primary Alveolar Type II Cells in Smokers

(2016) Karim Bahmed et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

(2016) Man J. Livingston et al.   Autophagy

Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose

(2016) Zi-Ying Shen et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents

(2016) Marwa Eltoweissy et al.   Molecular BioSystems

DJ-1/PARK7, But Not Its L166P Mutant Linked to Autosomal Recessive Parkinsonism, Modulates the Transcriptional Activity of the Orphan Nuclear Receptor Nurr1 In Vitro and In Vivo

(2016) Lingling Lu et al.   MOLECULAR NEUROBIOLOGY

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Role of Nuclear Factor Erythroid 2–Related Factor 2 in the Oxidative Stress–Dependent Hypertension Associated With the Depletion of DJ-1Novelty and Significance

(2015) Santiago Cuevas et al.   HYPERTENSION

Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression

(2015) M. A. Venkatachalam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Parkinson’s-associated protein DJ-1 regulates the 20S proteasome

(2015) Oren Moscovitz et al.   Nature Communications

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insights into the prognostic value of DJ-1 and MIB-1 in astrocytic tumors

(2013) Rasha M Abd El Atti et al.   Diagnostic Pathology

Neuroprotective Function of DJ-1 in Parkinson’s Disease

(2013) Hiroyoshi Ariga et al.   Oxidative Medicine and Cellular Longevity

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Proteomics analysis identifies PARK7 as an important player for renal cell resistance and survival under oxidative stress

(2011) Marwa Eltoweissy et al.   Molecular BioSystems

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Oxidative Stress Induction of DJ-1 Protein in Reactive Astrocytes Scavenges Free Radicals and Reduces Cell Injury

(2010) Takashi Yanagida et al.   Oxidative Medicine and Cellular Longevity