Lipid-Coated MCM-41 Mesoporous Silica Nanoparticles Loaded with Berberine Improved Inhibition of Acetylcholine Esterase and Amyloid Formation

Strategies for delivering therapeutics across the blood–brain barrier

(2021) Georg C. Terstappen et al.   NATURE REVIEWS DRUG DISCOVERY

Berberine Improves Behavioral and Cognitive Deficits in a Mouse Model of Alzheimer’s Disease via Regulation of β-Amyloid Production and Endoplasmic Reticulum Stress

(2021) Yubin Liang et al.   ACS Chemical Neuroscience

Functionalized mesoporous silica nanoparticles templated by pyridinium ionic liquid for hydrophilic and hydrophobic drug release application

(2020) Nurul Syahira Zaharudin et al.   Journal of Saudi Chemical Society

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

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Preparation of nanoliposomes by microfluidic mixing in herring-bone channel and the role of membrane fluidity in liposomes formation

(2020) Jan Kotouček et al.   Scientific Reports

Berberine attenuates Aβ42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells

(2020) Nan Zhang et al.   LIFE SCIENCES

Mixed Phospholipid Vesicles Catalytically Inhibit and Reverse Amyloid Fibril Formation

(2020) Andres F. Chaparro Sosa et al.   Journal of Physical Chemistry Letters

Bovine Serum Albumin Nanoparticles for the Efficient Delivery of Berberine: Preparation, Characterization and In vitro biological studies

(2020) Raghu Solanki et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Engineering precision nanoparticles for drug delivery

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Protective effect of surface-modified berberine nanoparticles against LPS-induced neurodegenerative changes: a preclinical study

(2019) Salma A. Soudi et al.   Drug Delivery and Translational Research

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity

(2019) Yulong Lin et al.   International Journal of Nanomedicine

Multidisciplinary Role of Mesoporous Silica Nanoparticles in Brain Regeneration and Cancers: From Crossing the Blood–Brain Barrier to Treatment

(2019) Shruti Mendiratta et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Berberine mitigates cognitive decline in an Alzheimer’s Disease Mouse Model by targeting both tau hyperphosphorylation and autophagic clearance

(2019) Ying Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Inorganic clay nanocomposite system for improved cholinesterase inhibition and brain pharmacokinetics of donepezil

(2019) Anurag Kumar Singh et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formation

(2018) Monika Rana et al.   INORGANICA CHIMICA ACTA

Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma

(2018) Yonghong Wang et al.   Journal of Biomedical Nanotechnology

Etoposide encapsulated functionalized mesoporous silica nanoparticles: Synthesis, characterization and effect of functionalization on dissolution kinetics in simulated and biorelevant media

(2018) Seema Saroj et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Berberine: Pathways to protect neurons

(2018) Xiaorui Lin et al.   PHYTOTHERAPY RESEARCH

Environmental impact of switching from the synthetic glucocorticoid prednisolone to the natural alkaloid berberine

(2018) Iris E. Allijn et al.   PLoS One

Biotinylated-lipid bilayer coated mesoporous silica nanoparticles for improving the bioavailability and anti-leukaemia activity of Tanshinone IIA

(2018) Zhe Li et al.   Artificial Cells Nanomedicine and Biotechnology

Jiao-Tai-Wan Improves Cognitive Dysfunctions through Cholinergic Pathway in Scopolamine-Treated Mice

(2018) Xin-Chen Wang et al.   Biomed Research International

MCM-41 Nanoparticles for Brain Delivery: Better Choline-Esterase and Amyloid Formation Inhibition with Improved Kinetics

(2018) Pawan Kumar Pandey et al.   ACS Biomaterials-Science & Engineering

MCM-41 Nanoparticles for Brain Delivery: Better Choline-Esterase and Amyloid Formation Inhibition with Improved Kinetics

(2018) Pawan Kumar Pandey et al.   ACS Biomaterials Science & Engineering

Lipid-Coated Mesoporous Silica Nanoparticles for the Delivery of the ML336 Antiviral to Inhibit Encephalitic Alphavirus Infection

(2018) Annette E. LaBauve et al.   Scientific Reports

Lipid-coated mesoporous silica microparticles for the controlled delivery of β-galactosidase into intestines

(2018) Ileana-Alexandra Pavel et al.   Journal of Materials Chemistry B

Effect of Chlorogenic Acid Supplementation in MPTP-Intoxicated Mouse

(2018) Saumitra S. Singh et al.   Frontiers in Pharmacology

Anti-Alzheimer's potential of berberine using surface decorated multi-walled carbon nanotubes: A preclinical evidence

(2017) Shikha Lohan et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Evaluation of brain-targeted chitosan nanoparticles through blood–brain barrier cerebral microvessel endothelial cells

(2017) Adem Sahin et al.   JOURNAL OF MICROENCAPSULATION

Nose to Brain Delivery of Rivastigmine by In Situ Gelling Cationic Nanostructured Lipid Carriers: Enhanced Brain Distribution and Pharmacodynamics

(2017) Preeti Wavikar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Layer-by-layer construction of lipid bilayer on mesoporous silica nanoparticle to improve its water suspensibility and hemocompatibility

(2017) Gaoxin Zhou et al.   JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY

Berberine attenuates cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and neuroinflammation

(2017) Wenbo He et al.   Pharmacological Reports

Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury

(2017) Da Xie et al.   Oncotarget

Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells

(2016) Paul N. Durfee et al.   ACS Nano

Response to Extreme Temperatures of Mesoporous Silica MCM-41: Porous Structure Transformation Simulation and Modification of Gas Adsorption Properties

(2016) Shenli Zhang et al.   LANGMUIR

Protocells: Modular Mesoporous Silica Nanoparticle-Supported Lipid Bilayers for Drug Delivery

(2016) Kimberly S. Butler et al.   Small

Development and characterization of solid dispersion-microsphere controlled release system for poorly water-soluble drug

(2016) Venkata Ramana Malipeddi et al.   Drug Delivery and Translational Research

A comparative study of the effects of cholesterol and desmosterol on zwitterionic DPPC model membranes

(2015) Cisem Altunayar et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Current knowledge and pharmacological profile of berberine: An update

(2015) Anil Kumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The therapeutic potential of berberine against the altered intrinsic properties of the CA1 neurons induced by Aβ neurotoxicity

(2015) Masoud Haghani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mesoporous silica nanoparticles in drug delivery and biomedical applications

(2015) Ying Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease

(2015) Linda Helmfors et al.   NEUROBIOLOGY OF DISEASE

Protective effect of berberine, an isoquinoline alkaloid ameliorates ethanol-induced oxidative stress and memory dysfunction in rats

(2015) Shaktipal Patil et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Targeted Treatment of Cancer with Nanotherapeutics Based on Mesoporous Silica Nanoparticles

(2015) Nikola Ž. Knežević et al.   ChemPlusChem

Berberine was neuroprotective against an in vitro model of brain ischemia: Survival and apoptosis pathways involved

(2014) Elisa Nicoloso Simões Pires et al.   BRAIN RESEARCH

Lipid coated mesoporous silica nanoparticles as an oral delivery system for targeting and treatment of intravacuolar Salmonella infections

(2014) Rajeev J. Mudakavi et al.   RSC Advances

Experimental and Mathematical Studies on the Drug Release Properties of Aspirin Loaded Chitosan Nanoparticles

(2014) Yixiang Shi et al.   Biomed Research International

Mesoporous Silica Nanoparticle Nanocarriers: Biofunctionality and Biocompatibility

(2013) Derrick Tarn et al.   ACCOUNTS OF CHEMICAL RESEARCH

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

(2013) Shashi Kant Tiwari et al.   ACS Nano

The eradication of breast cancer cells and stem cells by 8-hydroxyquinoline-loaded hyaluronan modified mesoporous silica nanoparticle-supported lipid bilayers containing docetaxel

(2013) Dong Wang et al.   BIOMATERIALS

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Effects of DPPC/Cholesterol liposomes on the properties of freshly precipitated calcium carbonate

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Bioavailability Study of Berberine and the Enhancing Effects of TPGS on Intestinal Absorption in Rats

(2011) Wei Chen et al.   AAPS PHARMSCITECH

Decrease in the production of beta-amyloid by berberine inhibition of the expression of beta-secretase in HEK293 cells

(2011) Feiqi Zhu et al.   BMC NEUROSCIENCE

Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease

(2011) Hong-Fang Ji et al.   MOLECULES

Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery

(2010) Sunil Kumar Battu et al.   AAPS PHARMSCITECH

Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

(2010) Y.-T. Liu et al.   DRUG METABOLISM AND DISPOSITION

Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats

(2010) Ashutosh Kumar et al.   FREE RADICAL RESEARCH

Lipid coated mesoporous silica nanoparticles as photosensitive drug carriers

(2010) Yang Yang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42

(2009) Verena H. Finder et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of lactational exposure to benzo[α]pyrene (B[α]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice

(2009) Jaouad Bouayed et al.   TOXICOLOGY

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

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Effect of surface concentration on secondary and tertiary conformational changes of lysozyme adsorbed on silica nanoparticles

(2008) Xiaoyu Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Interaction of Nanoparticles with Lipid Membrane

(2008) Yuri Roiter et al.   NANO LETTERS

The phosphorylation state of Ser-129 in human  -synuclein determines neurodegeneration in a rat model of Parkinson disease

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