Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial

Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma

(2021) Andrew Menzies-Gow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma

(2020) Gail M. Gauvreau et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Airway Remodeling in Asthma

(2020) Kenneth P. Hough et al.   Frontiers in Medicine

TSLP: from allergy to cancer

(2019) Jonathan Corren et al.   NATURE IMMUNOLOGY

IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

(2019) Martijn L. Manson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma

(2018) William W. Busse et al.   ADVANCES IN THERAPY

Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial

(2018) Richard J Russell et al.   Lancet Respiratory Medicine

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

(2018) William W Busse et al.   Lancet Respiratory Medicine

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma

(2017) Katherine N. Cahill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tezepelumab in Adults with Uncontrolled Asthma

(2017) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

(2014) Gail M. Gauvreau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Interleukin-13 in Asthma

(2013) Jonathan Corren   CURRENT ALLERGY AND ASTHMA REPORTS

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

(2013) Michel Laviolette et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic stromal lymphopoietin promotes asthmatic airway remodelling in human lung fibroblast cells through STAT3 signalling pathway

(2012) Jinxiang Wu et al.   CELL BIOCHEMISTRY AND FUNCTION

Mast Cell-Airway Smooth Muscle Crosstalk

(2011) Davinder Kaur et al.   CHEST

Lung damage and airway remodelling in severe asthma

(2011) C. E. Brightling et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE