Co-Regulated Genes and Gene Clusters

Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator

(2021) Aishwarya Gurumurthy et al.   NUCLEIC ACIDS RESEARCH

Interdependent evolution of biosynthetic gene clusters for momilactone production in rice

(2021) Naoki Kitaoka et al.   PLANT CELL

Genomic evidence for convergent evolution of gene clusters for momilactone biosynthesis in land plants

(2020) Lingfeng Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Liquid–Liquid Phase Separation in the Compartmentalization of Cell Nucleus and Spatial Genome Organization

(2020) S. V. Razin et al.   BIOCHEMISTRY-MOSCOW

Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts

(2020) Waritta Sawaengdee et al.   Frontiers in Genetics

The functional determinants in the organization of bacterial genomes

(2020) Zhaoqian Liu et al.   BRIEFINGS IN BIOINFORMATICS

GATA‐1‐dependent histone H3K27 acetylation mediates erythroid cell‐specific chromatin interaction between CTCF sites

(2020) Yea Woon Kim et al.   FASEB JOURNAL

Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization

(2020) Xiang Guo et al.   NUCLEIC ACIDS RESEARCH

Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis

(2020) Qian Qi et al.   BLOOD

Chromatin topology and the timing of enhancer function at theHoxDlocus

(2020) Eddie Rodríguez-Carballo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rise and fall of globins in the amphibia

(2020) João Pedro Fernandes Queiroz et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization

(2020) A Marieke Oudelaar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice

(2019) Kevin Monahan et al.   NATURE

Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice

(2019) Daniele Canzio et al.   CELL

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

(2019) Eddie Rodríguez-Carballo et al.   BMC BIOLOGY

Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells

(2019) Angels Almenar-Queralt et al.   NATURE GENETICS

Super-enhancers in transcriptional regulation and genome organization

(2019) Xi Wang et al.   NUCLEIC ACIDS RESEARCH

Genetic and Epigenetic Mechanisms of β-Globin Gene Switching

(2018) O. V. Iarovaia et al.   BIOCHEMISTRY-MOSCOW

Evolution of hemoglobin loci and their regulatory elements

(2018) Sjaak Philipsen et al.   BLOOD CELLS MOLECULES AND DISEASES

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

(2018) Nan Liu et al.   CELL

Gene Turnover and Diversification of the α- and β-Globin Gene Families in Sauropsid Vertebrates

(2018) Federico G Hoffmann et al.   Genome Biology and Evolution

Coactivator condensation at super-enhancers links phase separation and gene control

(2018) Benjamin R. Sabari et al.   SCIENCE

Metabolic Gene Clusters in Eukaryotes

(2018) Hans-Wilhelm Nützmann et al.   Annual Review of Genetics

Phase Separation and Transcription Regulation: Are Super-Enhancers and Locus Control Regions Primary Sites of Transcription Complex Assembly?

(2018) Aishwarya Gurumurthy et al.   BIOESSAYS

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

(2018) Lei Yu et al.   GENES & DEVELOPMENT

Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods

(2018) Fei Sun et al.   MOLECULAR CELL

Evolution of the Genome 3D Organization: Comparison of Fused and Segregated Globin Gene Clusters

(2017) Anastasia P. Kovina et al.   MOLECULAR BIOLOGY AND EVOLUTION

Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

(2017) Lars L. P. Hanssen et al.   NATURE CELL BIOLOGY

Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure

(2017) Sergey V. Ulianov et al.   Epigenetics & Chromatin

A long-range cis-regulatory element for class I odorant receptor genes

(2017) Tetsuo Iwata et al.   Nature Communications

Analysis of the relationship between coexpression domains and chromatin 3D organization

(2017) María E. Soler-Oliva et al.   PLoS Computational Biology

Erythroid activator NF-E2, TAL1 and KLF1 play roles in forming the LCR HSs in the human adult β-globin locus

(2016) Yea Woon Kim et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

(2016) Yu-Cheng Tsai et al.   NUCLEIC ACIDS RESEARCH

Gene Duplication and Evolutionary Innovations in Hemoglobin-Oxygen Transport

(2016) Jay F. Storz   PHYSIOLOGY

TADs as modular and dynamic units for gene regulation by hormones

(2015) François Le Dily et al.   FEBS LETTERS

Function and evolution of vertebrate globins

(2014) T. Burmester et al.   Acta Physiologica

Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation

(2014) François Le Dily et al.   GENES & DEVELOPMENT

Hox gene regulation and timing in embryogenesis

(2014) Thomas Montavon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The rise of operon-like gene clusters in plants

(2014) Svetlana Boycheva et al.   TRENDS IN PLANT SCIENCE

Conservation of globin genes in the “living fossil” Latimeria chalumnae and reconstruction of the evolution of the vertebrate globin family

(2013) Kim Schwarze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Neuroglobins, Pivotal Proteins Associated with Emerging Neural Systems and Precursors of Metazoan Globin Diversity

(2013) Christophe Lechauve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Biologically Relevant Enhancers in Human Erythroid Cells

(2013) Mack Y. Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs

(2013) G. Andrey et al.   SCIENCE

Evolution of Hemoglobin and Its Genes

(2013) R. C. Hardison   Cold Spring Harbor Perspectives in Medicine

Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR

(2012) Jared J. Ganis et al.   DEVELOPMENTAL BIOLOGY

Gene duplication, genome duplication, and the functional diversification of vertebrate globins

(2012) Jay F. Storz et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

CTCF/cohesin-mediated DNA looping is required for protocadherin   promoter choice

(2012) Y. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial organization of the chicken beta-globin gene domain in erythroid cells of embryonic and adult lineages

(2012) Sergey V Ulianov et al.   Epigenetics & Chromatin

Regulation of the Probability of Mouse Odorant Receptor Gene Choice

(2011) Mona Khan et al.   CELL

Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic  -Type Globin Promoters in Differentiated Adult Erythroid Cells

(2011) S. Cui et al.   MOLECULAR AND CELLULAR BIOLOGY

Whole-Genome Duplications Spurred the Functional Diversification of the Globin Gene Superfamily in Vertebrates

(2011) Federico G. Hoffmann et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Membrane-Bound Vertebrate Globin

(2011) Miriam Blank et al.   PLoS One

Trans -splicing

(2011) Erika L. Lasda et al.   Wiley Interdisciplinary Reviews-RNA

Globin gene structure in a reptile supports the transpositional model for amniote α- and β-globin gene evolution

(2010) Vidushi S. Patel et al.   CHROMOSOME RESEARCH

A spectrum of gene regulatory phenomena at mammalian β-globin gene lociThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2009) George Fromm et al.   Biochemistry and Cell Biology

Chromosome looping at the human  -globin locus is mediated via the major upstream regulatory element (HS -40)

(2009) D. Vernimmen et al.   BLOOD

Pigmentation Pathway Evolution after Whole-Genome Duplication in Fish

(2009) Ingo Braasch et al.   Genome Biology and Evolution

The Endothelin System: Evolution of Vertebrate-Specific Ligand-Receptor Interactions by Three Rounds of Genome Duplication

(2009) I. Braasch et al.   MOLECULAR BIOLOGY AND EVOLUTION

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells

(2009) Stefan Schoenfelder et al.   NATURE GENETICS

TMEM8 – a non-globin gene entrapped in the globin web

(2009) Elena S. Philonenko et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Temporal Control of Mouse Hox Genes in Vivo

(2009) N. Soshnikova et al.   SCIENCE

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals

(2008) Vidushi S Patel et al.   BMC BIOLOGY

Genome duplication and the origin of the vertebrate skeleton

(2008) GuangJun Zhang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Spatial configuration of the chicken α-globin gene domain: immature and active chromatin hubs

(2008) Alexey A. Gavrilov et al.   NUCLEIC ACIDS RESEARCH

The role of transcriptional activator GATA-1 at human  -globin HS2

(2008) Y. Cho et al.   NUCLEIC ACIDS RESEARCH

Genomic evidence for independent origins of  -like globin genes in monotremes and therian mammals

(2008) J. C. Opazo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexpression, coregulation, and cofunctionality of neighboring genes in eukaryotic genomes

(2007) Pawel Michalak   GENOMICS