Baicalin Attenuates Oxygen–Glucose Deprivation/Reoxygenation–Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron–Astrocyte Cocultures
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Baicalin Attenuates Oxygen–Glucose Deprivation/Reoxygenation–Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron–Astrocyte Cocultures
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-06-21
DOI
10.3389/fphar.2021.599543
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Brain-Derived Neurotrophic Factor and Its Potential Therapeutic Role in Stroke Comorbidities
- (2020) Wei Liu et al. NEURAL PLASTICITY
- In vitro modeling of the neurovascular unit: advances in the field
- (2020) Aditya Bhalerao et al. Fluids and Barriers of the CNS
- Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation
- (2020) Xianrui Song et al. Redox Biology
- Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells
- (2020) Marjolein Heymans et al. Fluids and Barriers of the CNS
- Axonogenesis Is Coordinated by Neuron-Specific Alternative Splicing Programming and Splicing Regulator PTBP2
- (2019) Min Zhang et al. NEURON
- A systematic review and meta-analysis of interventions to increase stroke thrombolysis
- (2019) Mollie McDermott et al. BMC Neurology
- Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system
- (2019) Changxiang Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles
- (2019) Sylwia Dabrowska et al. Journal of Neuroinflammation
- Cell-based and pharmacological neurorestorative therapies for ischemic stroke
- (2018) Poornima Venkat et al. NEUROPHARMACOLOGY
- Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy
- (2018) Ming-Shuo Sun et al. Oxidative Medicine and Cellular Longevity
- Global Burden of Stroke
- (2018) Mira Katan et al. SEMINARS IN NEUROLOGY
- The roles of astrocyte in the brain pathologies following ischemic stroke
- (2018) Linlin Sun et al. BRAIN INJURY
- Baicalin Attenuates Subarachnoid Hemorrhagic Brain Injury by Modulating Blood-Brain Barrier Disruption, Inflammation, and Oxidative Damage in Mice
- (2017) Xianqing Shi et al. Oxidative Medicine and Cellular Longevity
- Targeting brain-derived neurotrophic factor in the medial thalamus for the treatment of central poststroke pain in a rodent model
- (2017) Hsi-Chien Shih et al. PAIN
- Baicalin promotes the viability of Schwann cells in vitro by regulating neurotrophic factors
- (2017) Wenpu Zuo et al. Experimental and Therapeutic Medicine
- The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review
- (2017) Wei Liang et al. Aging and Disease
- RETRACTED: In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
- (2017) Kohei Yamamizu et al. Stem Cell Reports
- Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP
- (2016) Y. Hong et al. JOURNAL OF NEUROSCIENCE
- Reactive astrocytes and therapeutic potential in focal ischemic stroke
- (2016) Gourav Roy Choudhury et al. NEUROBIOLOGY OF DISEASE
- “Targeting astrocytes in CNS injury and disease: A translational research approach”
- (2016) Angela R. Filous et al. PROGRESS IN NEUROBIOLOGY
- Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke
- (2016) Zhongwu Liu et al. PROGRESS IN NEUROBIOLOGY
- Astrocyte-derived phosphatidic acid promotes dendritic branching
- (2016) Yan-Bing Zhu et al. Scientific Reports
- SKF83959 Produces Antidepressant Effects in a Chronic Social Defeat Stress Model of Depression through BDNF-TrkB Pathway
- (2015) Bo Jiang et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Acupuncture reduced apoptosis and up-regulated BDNF and GDNF expression in hippocampus following hypoxia–ischemia in neonatal rats
- (2015) Yong Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor
- (2015) N. Miyamoto et al. JOURNAL OF NEUROSCIENCE
- Innate Inflammatory Responses in Stroke: Mechanisms and Potential Therapeutic Targets
- (2014) J.Y. Kim et al. CURRENT MEDICINAL CHEMISTRY
- Baicalin’s Therapeutic Time Window of Neuroprotection during Transient Focal Cerebral Ischemia and Its Antioxidative EffectsIn VitroandIn Vivo
- (2013) Fafeng Cheng et al. Evidence-based Complementary and Alternative Medicine
- A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat
- (2013) Qiang Xue et al. International Journal of Biological Sciences
- BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities
- (2013) G Quesseveur et al. Translational Psychiatry
- Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways
- (2011) Yonggang Cao et al. BRAIN RESEARCH BULLETIN
- Baicalin reduces the permeability of the blood–brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells
- (2011) Haiyan Zhu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease
- (2010) Akira Yoshii et al. Developmental Neurobiology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started