Establishment of patient‐derived organotypic tumor spheroid models for tumor microenvironment modeling

Patient-derived cancer modeling for precision medicine in colorectal cancer: beyond the cancer cell line

(2020) Dae Hee Pyo et al.   CANCER BIOLOGY & THERAPY

Tumor microenvironment complexity and therapeutic implications at a glance

(2020) Roghayyeh Baghban et al.   Cell Communication and Signaling

Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model

(2020) Asunción Martín-Ruiz et al.   Scientific Reports

Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

(2020) George M. Ramzy et al.   Cancers

Organoid Models of Tumor Immunology

(2020) Kanako Yuki et al.   TRENDS IN IMMUNOLOGY

The tumour microenvironment as an integrated framework to understand cancer biology

(2019) Rebeca Burgos-Panadero et al.   CANCER LETTERS

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

A Critical Need for Better Cancer Immunotherapy Models: Are Organotypic Tumor Spheroid Cultures the Answer?

(2018) Justin M. Balko et al.   Cancer Discovery

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

(2018) Hervé Tiriac et al.   Cancer Discovery

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

(2018) Amir R. Aref et al.   LAB ON A CHIP

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

(2017) Moritz Schütte et al.   Nature Communications

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

(2017) Russell W. Jenkins et al.   Cancer Discovery

Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal Cancer

(2017) Alba Cristobal et al.   Cell Reports

Organoids as Models for Neoplastic Transformation

(2016) James T. Neal et al.   Annual Review of Pathology-Mechanisms of Disease

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

(2016) Masayuki Fujii et al.   Cell Stem Cell

Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics

(2016) Joyce F. Liu et al.   CLINICAL CANCER RESEARCH

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

(2014) Eliah R. Shamir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From Bench to Bedside: Lessons Learned in Translating Preclinical Studies in Cancer Drug Development

(2013) C. H. Lieu et al.   JNCI-Journal of the National Cancer Institute

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY