Amplification of oxidative stress with lycorine and gold-based nanocomposites for synergistic cascade cancer therapy

Lycorine hydrochloride induces reactive oxygen species‑mediated apoptosis via the mitochondrial apoptotic pathway and the JNK signaling pathway in the oral squamous cell carcinoma HSC‑3 cell line

(2021) Min-Hui Li et al.   Oncology Letters

Mitochondriopathies as a Clue to Systemic Disorders—Analytical Tools and Mitigating Measures in Context of Predictive, Preventive, and Personalized (3P) Medicine

(2021) Alena Liskova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways

(2021) Ping Zhang et al.   ONCOLOGY REPORTS

Mechanisms of Resistance to Conventional Therapies for Osteosarcoma

(2021) Louise Marchandet et al.   Cancers

Mitochondrial Dysfunction and Oxidative Stress Caused by Cryopreservation in Reproductive Cells

(2021) Roberto Gualtieri et al.   Antioxidants

Designing immunogenic nanotherapeutics for photothermal-triggered immunotherapy involving reprogramming immunosuppression and activating systemic antitumor responses

(2020) Jing Wang et al.   BIOMATERIALS

Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma

(2020) Xin Huang et al.   Acta Biomaterialia

Surface engineering of nanoparticles with ligands for targeted delivery to osteosarcoma

(2020) Xin Huang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress

(2020) Zhenchuan Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Design of Targeted Nanostructured Coordination Polymers (NCPs) for Cancer Therapy

(2020) Fernando Novio   MOLECULES

Self-Amplification of Tumor Oxidative Stress with Degradable Metallic Complexes for Synergistic Cascade Tumor Therapy

(2020) Gui Chen et al.   NANO LETTERS

Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual‐Sensitive Nanoreservoir of Triptolide

(2020) Hai‐Jun Liu et al.   Small

Anticancer activities of TCM and their active components against tumor metastasis

(2020) Kailong Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Endoplasmic Reticulum Stress Provocation by Different Nanoparticles: An Innovative Approach to Manage the Cancer and Other Common Diseases

(2020) Amjad Ali Khan et al.   MOLECULES

Dual-targeting nanoparticles with core-crosslinked and pH/redox-bioresponsive properties for enhanced intracellular drug delivery

(2019) Junqiang Zhao et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies

(2019) Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lycorine exerts antitumor activity against osteosarcoma cells in vitro and in vivo xenograft model through the JAK2/STAT3 pathway

(2019) Hongzhi Hu et al.   OncoTargets and Therapy

Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation

(2019) Wu-yi Liu et al.   Frontiers in Pharmacology

Gold nanorods based multicompartment mesoporous silica composites as bioagents for highly efficient photothermal therapy

(2019) Jie Zhao et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Lycorine Induces Apoptosis and G1 Phase Arrest Through ROS/p38 MAPK Signaling Pathway in Human Osteosarcoma cells in vitro and in vivo

(2019) Lei Ning et al.   SPINE

Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer

(2019) Sneha Mahalunkar et al.   International Journal of Nanomedicine

Gold nanourchins induce cellular stress, impair proteostasis and damage RNA

(2019) Dana M. Samhadaneh et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fermi level-tuned optics of graphene for attocoulomb-scale quantification of electron transfer at single gold nanoparticles

(2019) Qing Xia et al.   Nature Communications

Bruceine D inhibits tumor growth and stem cell‐like traits of osteosarcoma through inhibition of STAT3 signaling pathway

(2019) Shangyu Wang et al.   Cancer Medicine

pH-sensitive prodrug conjugated polydopamine for NIR-triggered synergistic chemo-photothermal therapy

(2018) Huaihong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mesoporous silica-coated gold nanostars with drug payload for combined chemo-photothermal cancer therapy

(2018) Gaoxing Su et al.   JOURNAL OF DRUG TARGETING

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

(2018) Milan Hano et al.   MOLECULES

Resonance Energy Transfer-Promoted Photothermal and Photodynamic Performance of Gold–Copper Sulfide Yolk–Shell Nanoparticles for Chemophototherapy of Cancer

(2018) Yun Chang et al.   NANO LETTERS

Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release

(2018) Andy Hernández Montoto et al.   ACS Applied Materials & Interfaces

Lycorine: A prospective natural lead for anticancer drug discovery

(2018) Mridul Roy et al.   BIOMEDICINE & PHARMACOTHERAPY

Enhancing Osteosacoma Killing and CT Imaging Using Ultrahigh Drug Loading and NIR-Responsive Bismuth Sulfide@Mesoporous Silica Nanoparticles

(2018) Yao Lu et al.   Advanced Healthcare Materials

Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy

(2018) Ziliang Dong et al.   NANO LETTERS

Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes

(2018) Chengyong He et al.   Nanotoxicology

Folic acid-tagged titanium dioxide nanoparticles for enhanced anticancer effect in osteosarcoma cells

(2017) Jin-wei Ai et al.   Materials Science & Engineering C-Materials for Biological Applications

Mitochondria and nuclei dual-targeted heterogeneous hydroxyapatite nanoparticles for enhancing therapeutic efficacy of doxorubicin

(2016) Hui Xiong et al.   BIOMATERIALS

Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy

(2015) Harutaka Mekaru et al.   ADVANCED DRUG DELIVERY REVIEWS

Rational assembly of a biointerfaced core@shell nanocomplex towards selective and highly efficient synergistic photothermal/photodynamic therapy

(2015) Chenchen Qin et al.   Nanoscale

Gold Nanorods Coated with Mesoporous Silica Shell as Drug Delivery System for Remote Near Infrared Light-Activated Release and Potential Phototherapy

(2015) Ji Liu et al.   Small

Au Nanomatryoshkas as Efficient Near-Infrared Photothermal Transducers for Cancer Treatment: Benchmarking against Nanoshells

(2014) Ciceron Ayala-Orozco et al.   ACS Nano

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Selective inhibition of breast cancer stem cells by gold nanorods mediated plasmonic hyperthermia

(2014) Yingying Xu et al.   BIOMATERIALS

Radiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticles

(2014) Hironobu Yasui et al.   CANCER LETTERS

Single-Step Assembly of DOX/ICG Loaded Lipid–Polymer Nanoparticles for Highly Effective Chemo-photothermal Combination Therapy

(2013) Mingbin Zheng et al.   ACS Nano

Polyethyleneimine-mediated synthesis of folic acid-targeted iron oxide nanoparticles for in vivo tumor MR imaging

(2013) Jingchao Li et al.   BIOMATERIALS

Investigating the Multiple Roles of Polyvinylpyrrolidone for a General Methodology of Oxide Encapsulation

(2013) Hang Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish

(2013) Verena Christen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cytochrome c oxidase dysfunction in oxidative stress

(2012) Satish Srinivasan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of the Nanogold Particle-Induced Endoplasmic Reticulum Stress by Omic Techniques and Systems Biology Analysis

(2011) Yen-Yin Tsai et al.   ACS Nano

Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay

(2008) Y HWANG et al.   ANTIVIRAL RESEARCH

A review of stimuli-responsive nanocarriers for drug and gene delivery

(2008) Srinivas Ganta et al.   JOURNAL OF CONTROLLED RELEASE