Prediction of CYP2D6 phenotype from genotype across world populations

CYP450 genotype and pharmacogenetic association studies: a critical appraisal

(2016) Rashmi R Shah et al.   PHARMACOGENOMICS

Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

(2016) Roland Keller et al.   PLoS Computational Biology

Effects of the CYP2D6*10 allele on the pharmacokinetics of atomoxetine and its metabolites

(2015) Ji-Yeong Byeon et al.   ARCHIVES OF PHARMACAL RESEARCH

In vivoassessment of the metabolic activity of CYP2D6 diplotypes and alleles

(2015) Daniel L. Hertz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting

(2015) LV Kalman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

(2015) JK Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol

(2015) Patteet Lisbeth et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6

(2015) Wanqiong Qiao et al.   HUMAN MUTATION

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

(2014) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Challenges in CYP2D6 Phenotype Assignment from Genotype Data: A Critical Assessment and Call for Standardization

(2014) J. Hicks et al.   CURRENT DRUG METABOLISM

Interethnic variability ofCYP2D6alleles and of predicted and measured metabolic phenotypes across world populations

(2014) Adrián LLerena et al.   Expert Opinion on Drug Metabolism & Toxicology

Functional characterization of CYP2D6 enhancer polymorphisms

(2014) Danxin Wang et al.   HUMAN MOLECULAR GENETICS

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants

(2013) J K Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity

(2013) Danxin Wang et al.   HUMAN MOLECULAR GENETICS

CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

(2011) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetics, Safety, and Tolerability of Atomoxetine and Effect ofCYP2D6*10/*10Genotype in Healthy Japanese Men

(2011) A. Matsui et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Gene copy number variations: it is important to determine which allele is affected

(2011) Anuradha Ramamoorthy et al.   PHARMACOGENOMICS

Composite Functional Genetic and Comedication CYP2D6 Activity Score in Predicting Tamoxifen Drug Exposure Among Breast Cancer Patients

(2010) Silvana Borges et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

(2010) Duanpen Sandee et al.   Pharmacogenetics and Genomics

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

(2010) Andrea Gaedigk et al.   Frontiers in Pharmacology

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

(2009) Shu-Feng Zhou   CLINICAL PHARMACOKINETICS

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

(2009) Shu-Feng Zhou   CLINICAL PHARMACOKINETICS

CYP2D7–2D6hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

(2009) Andrea Gaedigk et al.   PHARMACOGENOMICS

Genetic polymorphism of hepatocyte nuclear factor-4α influences human cytochrome P450 2D6 activity

(2008) Sang Seop Lee et al.   HEPATOLOGY