Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants

(2013) J K Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Relevance of “Missing Heritability ” in Pharmacogenomics

(2012) W Sadee   CLINICAL PHARMACOLOGY & THERAPEUTICS

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Cholesteryl Ester Transfer Protein (CETP) Polymorphisms Affect mRNA Splicing, HDL Levels, and Sex-Dependent Cardiovascular Risk

(2012) Audrey C. Papp et al.   PLoS One

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy

(2011) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

(2011) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity

(2011) Danxin Wang et al.   Pharmacogenetics and Genomics

CYP2D6,SULT1A1andUGT2B17copy number variation: quantitative detection by multiplex PCR

(2011) Andrea Gaedigk et al.   PHARMACOGENOMICS

Assessment of Activity Levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 Genes by Population Pharmacokinetics of Dextromethorphan

(2010) K Abduljalil et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms

(2010) Ryan M Smith et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

(2010) X. Yang et al.   GENOME RESEARCH

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

(2010) D Wang et al.   PHARMACOGENOMICS JOURNAL

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

(2010) Andrea Gaedigk et al.   Frontiers in Pharmacology

CYP2D7–2D6hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

(2009) Andrea Gaedigk et al.   PHARMACOGENOMICS

Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement

(2008) D. Wang et al.   BLOOD

Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A-B, 18, 27, 36, 39, 47-51, 53-55, and 57)

(2008) K. Sakuyama et al.   DRUG METABOLISM AND DISPOSITION

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY