Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

Bacillus subtilis PcrA Helicase Removes Trafficking Barriers

(2021) María Moreno-del Álamo et al.   Cells

Interaction with single‐stranded DNA‐binding protein localizes ribonuclease HI to DNA replication forks and facilitates R‐loop removal

(2020) Christine Wolak et al.   MOLECULAR MICROBIOLOGY

Bacillus subtilis PcrA Couples DNA Replication, Transcription, Recombination and Segregation

(2020) María Moreno-del Alamo et al.   Frontiers in Molecular Biosciences

UvrD helicase–RNA polymerase interactions are governed by UvrD’s carboxy-terminal Tudor domain

(2020) Ashish A. Kawale et al.   Communications Biology

Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD

(2020) Timothy P. Newing et al.   Nature Communications

The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling

(2020) Hao-Hong Pei et al.   Nature Communications

Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

(2019) Andy M C Lau et al.   BIOINFORMATICS

Direct removal of RNA polymerase barriers to replication by accessory replicative helicases

(2019) Michelle Hawkins et al.   NUCLEIC ACIDS RESEARCH

R-Loops as Cellular Regulators and Genomic Threats

(2019) Madzia P. Crossley et al.   MOLECULAR CELL

UvrD helicase activation by MutL involves rotation of its 2B subdomain

(2019) Yerdos A. Ordabayev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide relationship between R-loop formation and antisense transcription in Escherichia coli

(2018) Nalini Raghunathan et al.   NUCLEIC ACIDS RESEARCH

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Regulation of UvrD Helicase Activity by MutL

(2018) Yerdos A. Ordabayev et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β2-Microglobulin

(2018) Owen Cornwell et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mfd translocase is necessary and sufficient for transcription-coupled repair inEscherichia coli

(2017) Ogun Adebali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters

(2017) Liang Chen et al.   MOLECULAR CELL

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

(2017) Kelly Sanders et al.   NUCLEIC ACIDS RESEARCH

Genome-wide transcription-coupled repair inEscherichia coliis mediated by the Mfd translocase

(2017) Ogun Adebali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Bacillus BioBrick Box 2.0: expanding the genetic toolbox for the standardized work with Bacillus subtilis

(2017) Philipp F. Popp et al.   Scientific Reports

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

(2017) Gemma LM Fisher et al.   eLife

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis

(2017) Byoung-Mo Koo et al.   Cell Systems

MutS2 Promotes Homologous Recombination in Bacillus subtilis

(2016) Peter E. Burby et al.   JOURNAL OF BACTERIOLOGY

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

Rethinking transcription coupled DNA repair

(2015) Venu Kamarthapu et al.   CURRENT OPINION IN MICROBIOLOGY

Structural basis for transcription reactivation by RapA

(2015) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The B. subtilis Accessory Helicase PcrA Facilitates DNA Replication through Transcription Units

(2015) Christopher N. Merrikh et al.   PLoS Genetics

UvrD facilitates DNA repair by pulling RNA polymerase backwards

(2014) Vitaly Epshtein et al.   NATURE

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Profiling of Yeast DNA:RNA Hybrid Prone Sites with DRIP-Chip

(2014) Yujia A. Chan et al.   PLoS Genetics

The Conserved C-Terminus of the PcrA/UvrD Helicase Interacts Directly with RNA Polymerase

(2013) Emma J. Gwynn et al.   PLoS One

Prokaryotic Nucleotide Excision Repair

(2013) C. Kisker et al.   Cold Spring Harbor Perspectives in Biology

R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli

(2013) Hallie Wimberly et al.   Nature Communications

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

Structure and mechanism of the UvrA–UvrB DNA damage sensor

(2012) Danaya Pakotiprapha et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Perceiving the epigenetic landscape through histone readers

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB–DNA complexes

(2012) Matthew P. J. Webster et al.   NUCLEIC ACIDS RESEARCH

Superfamily I helicases as modular components of DNA-processing machines

(2011) Mark S. Dillingham   BIOCHEMICAL SOCIETY TRANSACTIONS

Representative Proteomes: A Stable, Scalable and Unbiased Proteome Set for Sequence Analysis and Functional Annotation

(2011) Chuming Chen et al.   PLoS One

The dynamic protein partnership of RNA polymerase inBacillus subtilis

(2011) Olivier Delumeau et al.   PROTEOMICS

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

(2010) Myunggon Ko et al.   NATURE

RepD-mediated recruitment of PcrA helicase at the Staphylococcus aureus pC221 plasmid replication origin, oriD

(2010) C. Machón et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction

(2010) Lars F. Westblade et al.   NUCLEIC ACIDS RESEARCH

The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair

(2009) Laura Manelyte et al.   DNA REPAIR

The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo

(2009) Hasna Boubakri et al.   EMBO JOURNAL

Molecular Evolution of Multisubunit RNA Polymerases: Structural Analysis

(2009) William J. Lane et al.   JOURNAL OF MOLECULAR BIOLOGY

Rep Provides a Second Motor at the Replisome to Promote Duplication of Protein-Bound DNA

(2009) Colin P. Guy et al.   MOLECULAR CELL

Structural frameworks for considering microbial protein- and nucleic acid-dependent motor ATPases

(2008) Nathan D. Thomsen et al.   MOLECULAR MICROBIOLOGY