Article
Environmental Sciences
Teemu Karkela, Unto Tapper, Tuula Kajolinna
Summary: The study compared the smoke from a research cigarette with the aerosol generated by IQOS, finding that IQOS aerosol emissions were significantly lower than cigarette smoke under the same puffing regimen. Despite similar maximum nicotine concentrations within a puff for both 3R4F smoke and IQOS aerosol, the average concentration was lower for IQOS aerosol. Additionally, water constituted a significant portion of particulate matter in both products, with higher levels in the IQOS aerosol.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Substance Abuse
Lauren Kass Lempert, Stanton Glantz
Summary: After analyzing FDA's review of PMPSA's application, relevant law and guidance on PMTAs, and independent research on IQOS health impacts, it was found that the evidence submitted did not demonstrate long-term disease risk reduction, and that IQOS aerosol emits toxins with carcinogenic and genotoxic potential. Despite recommendations from FDA scientists and independent research showing serious risks associated with IQOS, FDA concluded that it is 'appropriate for the protection of the public health', which may have significant health impacts and undermine public confidence in future PMTA decisions.
Article
Substance Abuse
Sarah Maloney, Alisha Eversole, Melanie Crabtree, Eric Soule, Thomas Eissenberg, Alison Breland
Summary: Among smokers, JUUL and IQOS delivered less nicotine than cigarettes. Also, in this sample, IQOS and OB reduced abstinence symptoms more effectively than JUUL. Additional work with experienced JUUL and IQOS users is needed, as their nicotine delivery profiles and subjective experiences may differ.
Article
Physiology
Naoko Arano Nitta, Tadashi Sato, Moegi Komura, Hitomi Yoshikawa, Yohei Suzuki, Aki Mitsui, Eriko Kuwasaki, Fumiyuki Takahashi, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi
Summary: This study found that chronic exposure to IQOS aerosol induces pulmonary emphysema predominantly via apoptosis-related pathways, suggesting that HTPs are not completely safe tobacco products.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2022)
Article
Substance Abuse
Sophie Braznell, J. Robert Branston, Anna B. Gilmore
Summary: This study analyzed the information and claims on the relative risks of IQOS made directly to potential consumers through the live webchat service on the IQOS website. The results showed that a variety of claims were used to indicate that IQOS is safer than cigarettes in successful webchat conversations in multiple countries.
Article
Chemistry, Multidisciplinary
J. Brian Jameson, Jiaming Wang, Patrick C. Bailey, Michael J. Oldham, Cameron R. Smith, Lena N. Jeong, David K. Cook, Austin L. Bates, Sifat Ullah, Alexander S. C. Pennington, I. Gene Gillman
Summary: This study reports on the effect of different aerosol collection strategies on the yields of chemical constituents in the aerosol of closed pod-based ENDS products. Collection strategies consisting of partial pod collection were valid for determining consistent yields of primary aerosol constituents, but variable yields were observed for certain metals, carbonyl compounds, and glycidol over the life of a pod. Whole pod collection increased sensitivity and accuracy in determining metal, carbonyl, and glycidol yields compared to partial pod collection.
FRONTIERS IN CHEMISTRY
(2023)
Article
Public, Environmental & Occupational Health
Jeeeun Yi, Cheol Min Lee, Seung-sik Hwang, Sung-il Cho
Summary: The study found that in South Korea, middle-aged individuals, those with higher income and education levels, as well as those with past vaping experience, were more likely to use heated tobacco products (HTPs). Additionally, current smoking behavior and motivation levels for smoking cessation were not significant predictors of future HTPs use.
Article
Substance Abuse
Anna Phillips-Waller, Dunja Przulj, Francesca Pesola, Katie Myers Smith, Peter Hajek
Summary: This study compared the nicotine delivery profile and user ratings of the IQOS heated tobacco system with cigarettes, Juul, and refillable e-cigarettes. Results showed that IQOS delivered less nicotine and received less favorable ratings compared to cigarettes and Juul. Compared to refillable e-cigarettes, IQOS delivered nicotine faster but received less favorable overall ratings.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
J. M. Martin-Alvarez, A. Almeida, A. A. Golpe, E. Asensio
Summary: This study aims to determine whether heated tobacco products (HTPs) in Spain adhered to regulations on tobacco advertising. The results indicate that the promotion of HTPs followed the same patterns as brands falsely perceived as healthier alternatives. Policy-makers should impose restrictions on marketing tobacco products that associate them with health to prevent an increase in smoking behavior.
Article
Environmental Sciences
Dong Kim, Jeongju Kim, Sang Joon Lee
Summary: The study showed that submicron water droplets are effective in removing indoor ultrafine particulate matter, with a removal efficiency approximately twice as high as micron-sized water droplets. The results also indicated that as the size of water droplets decreases, the efficiency of particulate matter collection increases significantly.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2021)
Article
Environmental Sciences
Ana Amoros-Perez, Laura Cano-Casanova, Maria del Carmen Roman-Martinez, Maria Angeles Lillo-Rodenas
Summary: A laboratory setup was used to collect and study particulate and soluble matter generated from cigarette smoke or Heets aerosol. The results showed that cigarettes produced higher levels of particulate matter and soluble compounds compared to Heets. The solid matter from cigarette smoke contained insoluble fractions and traces of heavy metals, while the samples from Heets were mainly composed of carbon and oxygen and soluble in isopropanol.
ENVIRONMENTAL RESEARCH
(2022)
Article
Substance Abuse
Teresa DeAtley, Matthew D. Stone, Andrew A. Strasser, Janet Audrain-McGovern
Summary: During the use of IQOS, smokers reduced their smoking frequency and increased motivation to quit smoking. IQOS risk perceptions did not directly account for the reduction in smoking, but may play an indirect role through increased use of IQOS.
Article
Orthopedics
Kazuya Nishino, Koji Tamai, Kumi Orita, Yusuke Hashimoto, Hiroaki Nakamura
Summary: The study found that heated tobacco products (HTP) have a negative impact on preosteoblast cell viability and bone fracture-healing, comparable to the effects of conventional cigarettes.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Orthopedics
Kazuya Nishino, Koji Tamai, Kumi Orita, Yusuke Hashimoto, Hiroaki Nakamura
Summary: The study showed that heated tobacco products (HTPs) have negative effects on preosteoblast cell viability, osteoblastic differentiation, and bone fracture-healing, comparable to the effects of conventional combustible cigarettes.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Public, Environmental & Occupational Health
Israel T. Agaku, Catherine O. Egbe, Olalekan A. Ayo-Yusuf
Summary: South Africa implemented sales restrictions on tobacco and related products as a public health measure during the COVID-19 pandemic, resulting in changes in marketing activities for novel tobacco products. Online sales data for e-cigarette liquids in South Africa during the restriction period showed that cannabidiol liquids were actively promoted by many vendors. Nielsen retail scanner data indicated a decrease in sales of heated tobacco products during the restriction, with a significant increase after the restriction was lifted, although total sales in September 2020 were lower than the previous year.
PREVENTIVE MEDICINE
(2021)
Article
Medicine, Legal
Maya I. Mitova, Pedro B. Campelos, Catherine G. Goujon-Ginglinger, Serge Maeder, Nicolas Mottier, Emmanuel G. R. Rouget, Manuel Tharin, Anthony R. Tricker
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Chemistry, Analytical
Nicolas Mottier, Manuel Tharin, Camille Cluse, Jean-Rene Crudo, Maria Gomez Lueso, Catherine G. Goujon-Ginglinger, Anne Jaquier, Maya I. Mitova, Emmanuel G. R. Rouget, Mathieu Schaller, Jennifer Solioz
Article
Plant Sciences
Gerhard Lang, Nor Ainy Mayhudin, Maya I. Mitova, Lin Sun, Sonia van der Sar, John W. Blunt, Anthony L. J. Cole, Gill Ellis, Hartmut Laatsch, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2008)
Article
Plant Sciences
Maya I. Mitova, Gerhard Lang, Jutta Wiese, Johannes F. Imhoff
JOURNAL OF NATURAL PRODUCTS
(2008)
Article
Plant Sciences
Maya I. Mitova, Annabel C. Murphy, Gerhard Lang, John W. Blunt, Anthony L. J. Cole, Gill Ellis, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2008)
Article
Plant Sciences
Annabel C. Murphy, Maya I. Mitova, John W. Blunt, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2008)
Article
Plant Sciences
E. Dilip de Silva, Anna-Skrollan Geiermann, Maya I. Mitova, Philipp Kuegler, John W. Blunt, Anthony L. J. Cole, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2009)
Article
Chemistry, Organic
Sonia A. van der Sar, Gerhard Lang, Maya I. Mitova, John W. Blunt, Anthony L. J. Cole, Nicholas Cummings, Gill Ellis, Murray H. G. Munro
JOURNAL OF ORGANIC CHEMISTRY
(2008)
Article
Biochemical Research Methods
Maria Gomez Lueso, Maya I. Mitova, Nicolas Mottier, Mathieu Schaller, Michel Rotach, Catherine G. Goujon-Ginglinger
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Plant Sciences
Gerhard Lang, Maya I. Mitova, Anthony L. J. Cole, Laily B. Din, Sabaratnam Vikineswary, Noorlidah Abdullah, John W. Blunt, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2006)
Article
Plant Sciences
Maya I. Mitova, Blair G. Stuart, Grace H. Cao, John W. Blunt, Anthony L. J. Cole, Murray H. G. Munro
JOURNAL OF NATURAL PRODUCTS
(2006)
Article
Chemistry, Organic
Chien-Hui Chen, Gerhard Lang, Maya I. Mitova, Annabel C. Murphy, Anthony L. J. Cole, Laily B. Din, John W. Blunt, Murray H. G. Munro
JOURNAL OF ORGANIC CHEMISTRY
(2006)
Article
Plant Sciences
G Lang, MI Mitova, G Ellis, S Van der Sar, RK Phipps, JW Blunt, NJ Cummings, ALJ Cole, MHG Munro
JOURNAL OF NATURAL PRODUCTS
(2006)
Article
Chemistry, Organic
MI Mitova, G Lang, JW Blunt, NJ Cummings, ALJ Cole, WT Robinson, MHG Munro
JOURNAL OF ORGANIC CHEMISTRY
(2006)