Human endogenous retrovirus K (HERV-K) env in neuronal extracellular vesicles: a new biomarker of motor neuron disease

Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism

(2020) Cheng Jiang et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K

(2020) Domenico Di Curzio et al.   Cells

Increased Interleukin-6 Levels in the Astrocyte-Derived Exosomes of Sporadic Amyotrophic Lateral Sclerosis Patients

(2019) Yong Chen et al.   Frontiers in Neuroscience

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

(2019) Oliver H. Tam et al.   Cell Reports

Humoral immunity response to human endogenous retroviruses K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases

(2018) G. Arru et al.   EUROPEAN JOURNAL OF NEUROLOGY

Human Endogenous Retroviruses in Neurological Diseases

(2018) Patrick Küry et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

(2018) Jens Mayer et al.   Molecular Neurodegeneration

Human endogenous retrovirus-K (HML-2): a comprehensive review

(2018) Marta Garcia-Montojo et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Growth Hormone-Releasing Hormone Modulation of Neuronal Exosome Biomarkers in Mild Cognitive Impairment

(2018) Charisse N. Winston et al.   JOURNAL OF ALZHEIMERS DISEASE

Exosome secretion is a key pathway for clearance of pathological TDP-43

(2016) Yohei Iguchi et al.   BRAIN

TDP-43 regulates endogenous retrovirus-K viral protein accumulation

(2016) Mamneet Manghera et al.   NEUROBIOLOGY OF DISEASE

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis

(2016) Jack van Horssen et al.   Multiple Sclerosis and Related Disorders

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding

(2015) Leslie I Grad et al.   Prion

Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia

(2014) Amandine Vargas et al.   FASEB JOURNAL

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

(2013) George R. Young et al.   BIOESSAYS

The endogenous retroviral envelope protein syncytin-1 inhibits LPS/PHA-stimulated cytokine responses in human blood and is sorted into placental exosomes

(2012) J.M. Tolosa et al.   PLACENTA

Age- and Disease-Dependent HERV-W Envelope Allelic Variation in Brain: Association with Neuroimmune Gene Expression

(2011) Rakesh K. Bhat et al.   PLoS One

Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

(2010) Renée Douville et al.   ANNALS OF NEUROLOGY

Structural and metabolic changes in the brain of patients with upper motor neuron disorders: A multiparametric MRI study

(2009) Arnaud Charil et al.   Amyotrophic Lateral Sclerosis

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease

(2008) Antonina Dolei et al.   JOURNAL OF NEUROVIROLOGY

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate

(2008) A. L. McCormick et al.   NEUROLOGY