Identification of functional farnesoid X receptors in brain neurons

Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure

(2016) Matthew McMillin et al.   AMERICAN JOURNAL OF PATHOLOGY

Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling

(2016) Avafia Y. Dossa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Alterations in the intrinsic electrophysiological properties of Purkinje neurons in a rat model of hepatic encephalopathy: Relative preventing effect of PPARγ agonist

(2016) Iraj Aghaei et al.   BRAIN RESEARCH BULLETIN

TGR5 signaling reduces neuroinflammation during hepatic encephalopathy

(2015) Matthew McMillin et al.   JOURNAL OF NEUROCHEMISTRY

Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes

(2015) Ahmad Sharanek et al.   TOXICOLOGICAL SCIENCES

Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

(2015) Fei Huang et al.   Frontiers in Behavioral Neuroscience

Role of farnesoid X receptor and bile acids in alcoholic liver disease

(2015) Sharon Manley et al.   Acta Pharmaceutica Sinica B

Farnesoid X Receptor Ligand Prevents Cisplatin-Induced Kidney Injury by Enhancing Small Heterodimer Partner

(2014) Eun Hui Bae et al.   PLoS One

Upregulation of thrombomodulin expression by activation of farnesoid X receptor in vascular endothelial cells

(2013) Xie He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TSG (2,3,4’ ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia

(2013) Chao Huang et al.   Journal of Neuroinflammation

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders

(2013) Vanesa Stepanov et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Bile acid receptors as targets for drug development

(2013) Frank G. Schaap et al.   Nature Reviews Gastroenterology & Hepatology

Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells

(2012) Divya P. Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

(2012) Jun Pu et al.   EUROPEAN HEART JOURNAL

Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter

(2011) Barbara Renga et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

TGR5: A Novel Target for Weight Maintenance and Glucose Metabolism

(2011) Xiaosong Chen et al.   Experimental Diabetes Research

Farnesoid X receptor represses hepatic human APOA gene expression

(2011) Indumathi Chennamsetty et al.   JOURNAL OF CLINICAL INVESTIGATION

The bile acid sensor FXR regulates insulin transcription and secretion

(2010) Barbara Renga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The nuclear receptor FXR is expressed in pancreatic β-cells and protects human islets from lipotoxicity

(2010) Iuliana Ristea Popescu et al.   FEBS LETTERS

The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

(2010) Verena Keitel et al.   GLIA

AKR1B7 Is Induced by the Farnesoid X Receptor and Metabolizes Bile Acids

(2010) Daniel R. Schmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile acids: Chemistry, physiology, and pathophysiology

(2009) Maria J Monte et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Bile-acid-induced cell injury and protection

(2009) Maria J Perez et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Coordinated Nuclear Receptor Regulation of the Efflux Transporter, Mrp2, and the Phase-Ii Metabolizing Enzyme, GSTπ, at the Blood—Brain Barrier

(2008) Björn Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM