Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain

Ketamine’s dose related multiple mechanisms of actions: Dissociative anesthetic to rapid antidepressant

(2020) Eli Lavender et al.   BEHAVIOURAL BRAIN RESEARCH

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

(2020) Phi T. Nguyen et al.   CELL

Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain

(2020) Joshua D. Crapser et al.   EBioMedicine

EEG 40 Hz Coherence Decreases in REM Sleep and Ketamine Model of Psychosis

(2019) Santiago Castro-Zaballa et al.   Frontiers in Psychiatry

NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity

(2019) Nathalie Picard et al.   MOLECULAR PSYCHIATRY

MMPs in learning and memory and neuropsychiatric disorders

(2019) Anna Beroun et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

(2019) James W. Fawcett et al.   NATURE REVIEWS NEUROSCIENCE

Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo

(2019) Yiting Liu et al.   EXPERIMENTAL NEUROLOGY

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Lack of metabolism in (R)-ketamine’s antidepressant actions in a chronic social defeat stress model

(2018) Kai Zhang et al.   Scientific Reports

Hyaluronic acid is present on specific perineuronal nets in the mouse cerebral cortex

(2018) Hiroshi Ueno et al.   BRAIN RESEARCH

Impact of repeated anesthesia with ketamine and xylazine on the well-being of C57BL/6JRj mice

(2018) Katharina Hohlbaum et al.   PLoS One

The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders

(2018) Teresa H. Wen et al.   Frontiers in Molecular Neuroscience

Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

(2018) Bhanu P. Tewari et al.   Nature Communications

Extracellular matrix alterations in the ketamine model of schizophrenia

(2017) Gabriela Matuszko et al.   NEUROSCIENCE

Sensory experience-dependent formation of perineuronal nets and expression of Cat-315 immunoreactive components in the mouse somatosensory cortex

(2017) Hiroshi Ueno et al.   NEUROSCIENCE

Region-specific impairments in parvalbumin interneurons in social isolation-reared mice

(2017) Hiroshi Ueno et al.   NEUROSCIENCE

Light reintroduction after dark exposure reactivates plasticity in adults via perisynaptic activation of MMP-9

(2017) Sachiko Murase et al.   eLife

Ketamine: differential neurophysiological dynamics in functional networks in the rat brain

(2017) A Ahnaou et al.   Translational Psychiatry

Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice

(2016) Connor Thelen et al.   BEHAVIOURAL BRAIN RESEARCH

Ketamine: 50 Years of Modulating the Mind

(2016) Linda Li et al.   Frontiers in Human Neuroscience

Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity

(2016) Kristian Kinden Lensjø et al.   JOURNAL OF NEUROSCIENCE

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

Rapid recovery from the effects of early monocular deprivation is enabled by temporary inactivation of the retinas

(2016) Ming-fai Fong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

(2016) G. O. Sipe et al.   Nature Communications

Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

(2016) Eitan S Kaplan et al.   eLife

Vital signs monitoring during injectable and inhalant anesthesia in mice

(2015) Atsushi TSUKAMOTO et al.   EXPERIMENTAL ANIMALS

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Proteolytic regulation of synaptic plasticity in the mouse primary visual cortex: analysis of matrix metalloproteinase 9 deficient mice

(2015) Emily A. Kelly et al.   Frontiers in Cellular Neuroscience

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

(2015) Sarah M. Reinhard et al.   Frontiers in Cellular Neuroscience

Optimal level activity of matrix metalloproteinases is critical for adult visual plasticity in the healthy and stroke-affected brain

(2015) Justyna Pielecka-Fortuna et al.   eLife

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Experience-dependent development of perineuronal nets and chondroitin sulfate proteoglycan receptors in mouse visual cortex

(2013) Qian Ye et al.   MATRIX BIOLOGY

A disinhibitory microcircuit initiates critical-period plasticity in the visual cortex

(2013) Sandra J. Kuhlman et al.   NATURE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Imaging Patients with Psychosis and a Mouse Model Establishes a Spreading Pattern of Hippocampal Dysfunction and Implicates Glutamate as a Driver

(2013) Scott A. Schobel et al.   NEURON

Sex differences in the antidepressant-like effects of ketamine

(2013) Nicole Carrier et al.   NEUROPHARMACOLOGY

Extracellular matrix inhibits structural and functional plasticity of dendritic spines in the adult visual cortex

(2013) L. de Vivo et al.   Nature Communications

Activity-Dependent Local Translation of Matrix Metalloproteinase-9

(2012) M. Dziembowska et al.   JOURNAL OF NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis

(2011) Emery N. Brown et al.   Annual Review of Neuroscience

Inhibition of Matrix Metalloproteinases Prevents the Potentiation of Nondeprived-Eye Responses after Monocular Deprivation in Juvenile Rats

(2011) M. Spolidoro et al.   CEREBRAL CORTEX

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron–glia signaling

(2011) R. Douglas Fields   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of matrix metalloproteinase activity in health and disease

(2010) Elin Hadler-Olsen et al.   FEBS Journal

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Interaction of Pro-matrix Metalloproteinase-9/Proteoglycan Heteromer with Gelatin and Collagen

(2008) Nabin Malla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinctive Features of Adult Ocular Dominance Plasticity

(2008) M. Sato et al.   JOURNAL OF NEUROSCIENCE

Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance

(2008) T. Bolmont et al.   JOURNAL OF NEUROSCIENCE

N-Methyl d-Aspartate Receptor Antagonists Ketamine and MK-801 Induce Wake-Related Aberrant γ Oscillations in the Rat Neocortex

(2007) Didier Pinault   BIOLOGICAL PSYCHIATRY