Article
Physics, Applied
Avishek Das, Arthur C. M. V. Pereira, Anton A. Popov, Andrei Pastukhov, Sergei M. Klimentov, Andrei V. Kabashin, Anderson S. L. Gomes
Summary: Photoacoustic imaging (PAI) is a promising noninvasive biomedical diagnostic technique, but lacks efficient nano-sized contrast agents. Researchers found that titanium nitride (TiN) nanoparticles synthesized by pulsed laser ablation in liquids can be used as a contrast agent in PAI. These nanoparticles exhibit a strong nonlinear photoacoustic response and can generate high-resolution images.
APPLIED PHYSICS LETTERS
(2022)
Review
Chemistry, Multidisciplinary
Sing Yee Ong, Changyu Zhang, Xiao Dong, Shao Q. Yao
Summary: This review discusses the recent advances in the use of polymeric nanoparticles for fluorescence and photoacoustic imaging, focusing on strategies for enhanced bioimaging applications such as encapsulating dyes and doping ions. Limitations in current systems are highlighted, along with potential solutions. Critical considerations for the design of polymeric NPs for future bioimaging and sensing applications are also discussed.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Analytical
Yujing Kong, Fang Yuan, Fei Yang, Cuiling Zhang, Yuezhong Xian
Summary: Controllable cell assembly and disassembly using reversible near-infrared light-induced interactions have significant implications. In this study, a NIR-controlled system based on S-cyclodextrin modified upconversion nanoparticles was developed for reversible manipulation of cell assembly, realized by host-guest interactions between arylazopyrazole and S-CD under NIR irradiation.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Lijun Ma, Yajie Cai, Shuo Li, Jiguang Li, Peiyu Chen, Grigory V. Zyryanov, Dmitry S. Kopchuk, Igor S. Kovalev, Zhuo Wang
Summary: In this study, three degradable semiconducting polymers with unique optical properties were developed by adjusting the molecular structure. By introducing degradable chemical groups, these polymers can be degraded in vivo. Successful in vivo photoacoustic imaging of arthritis mouse model was achieved using DPPTz NPs and DPPQu NPs.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Lijun Ma, Yajie Cai, Shuo Li, Jiguang Li, Peiyu Chen, Grigory V. Zyryanov, Dmitry S. Kopchuk, Igor S. Kovalev, Zhuo Wang
Summary: In this study, degradable semiconducting polymers with unique optical properties were developed by designing the molecular structure. By adjusting the donor and acceptor units, nanosize particles were synthesized and used for in vivo photoacoustic imaging in a mouse model. This work provides a new design idea for red-shifted semiconducting polymers with degradable properties.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Jianwen Song, Xiaoying Kang, Lu Wang, Dan Ding, Deling Kong, Wen Li, Ji Qi
Summary: Researchers have developed a polymer nanoplatform for thrombus imaging and treatment in the near-infrared-II region, offering a versatile approach for the diagnosis and treatment of life-threatening diseases caused by thrombotic disorders.
NATURE COMMUNICATIONS
(2023)
Article
Biochemical Research Methods
Zesheng Zheng, Anivind Kaur Bindra, Haoran Jin, Quqin Sun, Siyu Liu, Yuanjin Zheng
Summary: In this study, the phenomenon of collective optical/thermal enhancement in pulse-laser irradiated nanoparticle suspension is investigated, leading to nonlinear photoacoustic generation. The theory is validated using finite element method and experimentally proved with semiconducting polymer nanoparticles suspension, potentially paving a new direction for effective MDR based nonlinear PA contract agent design.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Chemistry, Analytical
Zeshun Li, Tingting Li, Chen Zhang, Jen-Shyang Ni, Yaoyao Ji, Aihui Sun, Dinglu Peng, Weijun Wu, Lei Xi, Kai Li
Summary: The study designed near-infrared absorbing semiconducting polymer nanoparticles to track the targeting behaviors of cells to inflammation sites and revealed the cell types' activities in the inflammation microenvironment through photoacoustic activity.
ANALYTICAL CHEMISTRY
(2021)
Review
Pharmacology & Pharmacy
Houjuan Zhu, Bofan Li, Chui Yu Chan, Beverly Low Qian Ling, Jiaqian Tor, Xin Yi Oh, Wenbin Jiang, Enyi Ye, Zibiao Li, Xian Jun Loh
Summary: Phototheranostic based on photothermal therapy (PTT) and photoacoustic imaging (PAI) is gaining attention due to its noninvasive, deeply penetrative, and highly selective and effective therapy. Single-component inorganic nanostructures are novel and attractive PAI and PTT combined nanotheranostic agents. They have controllable structure, tunable physiochemical properties, size-dependent optical properties, simple composition, and easy synthesis process. They also have multiple therapeutic and imaging functions, reducing systemic side effects and improving the bioavailability.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Article
Engineering, Environmental
Xianlei Li, Zi'an Pan, Chenyang Xiang, Yuan Yuan, Jing Chen, Guangchao Qing, Jing Ma, Xing-Jie Liang, Yan Wu, Weisheng Guo
Summary: Researchers have developed transformable CuS@GNPs nanoparticles that can undergo enzyme-induced multistage delivery, leading to enhanced accumulation at the tumor site and deeper penetration.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Jun Wang, Tingting Li, Jen-Shyang Ni, Heng Guo, Tianyi Kang, Zeshun Li, Menglei Zha, Songbo Lu, Chen Zhang, Weizhi Qi, Lei Xi, Kai Li
Summary: A novel photoacoustic force-guided nanotherapeutic system based on a near-infrared-absorbing semiconducting polymer has been reported, showing significantly improved tumor accumulation and deep tissue penetration for enhanced phototherapeutic efficacy.
Review
Chemistry, Multidisciplinary
Chao Yin, Xiaozhen Li, Yi Wang, Yuying Liang, Shan Zhou, Pengchao Zhao, Chun-Sing Lee, Quli Fan, Wei Huang
Summary: Organic semiconducting macromolecular dyes (OSMDs) are emerging as alternative candidates for NIR-II photoacoustic imaging (PAI) and photothermal therapy (PTT) due to their reliable biocompatibility, durable photostability, and ideal photothermal conversion capability. Their applications in the NIR-II optical window include tumor imaging, stem cell tracking, vasculature imaging, and tumor ablation.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Biochemical Research Methods
Fengshuo Wang, Anni Zhu, Jianhui Zhou, Yongtao Wang, Jingchao Li
Summary: Regulating gene expression plays a crucial role in understanding gene functions and potential therapeutic applications, but it remains challenging. Nonviral carriers have advantages over traditional physical delivery strategies in gene delivery, but controlling gene delivery to targeting regions is difficult, leading to off-target side effects. In contrast, light-responsive carriers can precisely control gene transgenic behaviors at specific locations and time, reducing off-target gene editing. This review summarizes the recent progress of NIR photoresponsive nanotransducers for precision regulation of gene expression.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Engineering, Biomedical
Tianyi Kang, Jen-Shyang Ni, Tingting Li, Jun Wang, Zeshun Li, Yaxi Li, Menglei Zha, Chen Zhang, Xue Wu, Heng Guo, Lei Xi, Kai Li
Summary: The study demonstrated for the first time that a near-infrared (NIR) pulse laser can efficiently guide delivery of miRNAs to targeted tumor sites, overcoming endothelial barriers. Rapid delivery of miR-7 was achieved under pulse laser irradiation, leading to a 5-fold increase in efficiency and effective tumor growth inhibition.
Article
Chemistry, Inorganic & Nuclear
Jiaxing Zhu, Yi Yu, Hongchuan Fan, Huaqiang Cai, Zhenxia Chen, Linhong Weng, Yun Ling, Yaming Zhou
Summary: In this study, a novel metal-organic framework material MAC-20 was designed to achieve a two-step pore-shape change. By precisely regulating the molecular structure, the material demonstrated the potential for sequential adsorption of specific molecules, presenting versatile responsive properties.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Zihan Yao, Xiaodong Wang, Jie Liu, Siyu Zhou, Zhe Zhang, Shuwen He, Jing Liu, Changfeng Wu, Xiaofeng Fang
Summary: Two photoswitchable semiconducting polymers were synthesized by incorporating photochromic dithienylethene (DTE) into the main chains. Small size polymer dots (Pdots) exhibited dynamic photoswitching behavior upon alternate light irradiation. With the tunable photoswitching properties, effective pattern encoding and superresolution imaging with a resolution of up to about 30 nm were achieved.
CHEMICAL COMMUNICATIONS
(2023)
Article
Optics
Xiaodong Wang, Dayan Li, Zhihe Liu, Xiaofeng Fang, Jiani Li, Tianyue Shi, Changfeng Wu
Summary: In the past decade, various methods have been proposed for optical imaging through scattering media. Among them, the speckle deconvolution method utilizing the optical memory effect of the medium is widely used due to its advantages in speed and setup simplicity. However, its practical applications are limited due to the requirement of direct incoherent illumination in existing systems. This study introduces an imaging system in reflection configuration, which can perform speckle deconvolution to retrieve hidden fluorescent objects behind thin scattering media.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Thermodynamics
Hongzhi Li, Yifan Zhang, Wengang Bai, Yu Yang, Kailun Li, Wei Gao, Lei Zhang, Chun Zhang, Shuaishuai Wu, Xuwei Zhang, Yongqiang Qiao, Yujia Zhou, Jiarong Wu
Summary: The development and control strategies of supercritical CO2 (sCO2) power system have been the focus of recent research, especially in terms of wide-range and rapid load regulation for large-scale utilization and commercialization. A pilot multi-megawatts SMART (Supercritical CO2 Modular Advanced Research and Test) fossil-fired power system has been successfully built and operated in China, demonstrating efficient and flexible operation within a wide range of load variations. The control modules implemented in the system effectively regulate key parameters to ensure stable operation and achieve load ramp and reduction rates significantly higher than steam power systems.
ENERGY CONVERSION AND MANAGEMENT
(2023)
Article
Chemistry, Inorganic & Nuclear
Ningning Sun, Yapei Yun, Kaikai Li, Xin Ni, Yao Qin, Xiaofei Yang, Hongting Sheng, Manzhou Zhu
Summary: Regulation of Hybrid Materials of Ministry of Education. Bimetallic nanoclusters with synergistic effect exhibit better stability and activity than monometallic nanoclusters in catalytic applications. The influence of calcination temperature on catalytic performance of AuCu24/AC in homocoupling and heterocoupling of terminal alkynes was investigated by fabricating AuCu24/AC-X (X=0, 200, 300, 500, 800) catalysts. The results showed that the catalytic activity of AuCu24/AC-X exhibited a volcanic trend with the increase of X (heat treatment temperature) and the content of Cu2+ also changed with the increase of X. The AuCu24/AC-200 bimetallic catalyst showed the highest catalytic activity in homocoupling and heterocoupling of terminal alkynes under mild conditions.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Environmental Sciences
Xinyu Yang, Kai Li, Chi Wang, Fei Wang, Xin Sun, Yixing Ma, Yuan Li, Lei Shi, Ping Ning
Summary: Non-thermal plasma (NTP) surface modification technology is a new method for controlling the surface properties of materials. In this study, Cu/ACF adsorbent was modified with NTP to remove H 2 S and PH 3 simultaneously under low temperature and micro-oxygen conditions. The performance test results showed that NH 3 plasma modification had the best removal effect on H 2 S and PH 3 . The NH 3 plasma modification introduced amino functional groups on the surface of the adsorbent and increased the types and number of alkaline sites, thereby improving the adsorption performance. The deactivation of the adsorbent was mainly caused by the consumption of active components and the accumulation of sulfate and phosphate on the surface and inner pores.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Plant Sciences
Ranran Wang, Jiaojiao Bai, Guofu Yan, Zejun Xiao, Kexin Chen, Kaikai Li, Jie Tang, Dongping Lu
Summary: This study found that enzymatic hydrolysate of fucoidan (FEH), derived from Sargassum hemiphyllum, can trigger various immune responses in plants, including ROS production, MAPK activation, gene expression reprogramming, callose deposition, stomatal closure, and plant resistance to Pseudomonas syringae pv. tomato (Pst) DC3000. Therefore, FEH has the potential to be used as a non-microbial elicitor to protect plants from pathogen infection in agricultural practices.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Materials Science, Biomaterials
Jingyu Xiao, Dishuang Yang, Xiaofeng Fang, Xiaoya Liu, Xuezhe Liu, Le Ma, Ziyan Wang, Changfeng Wu, Qiongyu Guo
Summary: Photothermal therapy has limitations in treating deep tissues due to the limited penetration depth of light. To overcome this, the strategy of endovascular photothermal precision embolization (EPPE) is introduced, which uses an endovascular optical fiber to induce local embolization and block the blood supply of the whole tumor. EPPE uses a highly efficient and biocompatible photothermal agent, which effectively kills cells both in 2D and 3D models. The feasibility of EPPE is verified in ex vivo liver models and in vivo rat liver models.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Dandan Chen, Weizhi Qi, Ye Liu, Yicheng Yang, Tianyue Shi, Yongchao Wang, Xiaofeng Fang, Yingjie Wang, Lei Xi, Changfeng Wu
Summary: Researchers have developed a method for high-contrast vascular imaging in deep tissues using fluorescent probes and imaging algorithms. By improving the brightness and compactness of the probes, and enhancing the image contrast using the Hessian matrix method, they achieved high-resolution imaging of small blood vessels. This study provides a promising approach for NIR-II fluorescence imaging of vascular structures in deep tissues.
Article
Biochemical Research Methods
Siyu Zhou, Xiaofeng Fang, Jiahui Lv, Yicheng Yang, Yiqi Zeng, Ying Liu, Weijun Wei, Gang Huang, Bo Zhang, Changfeng Wu
Summary: The immobilization of microbial transglutaminase (mTGase) on magnetic beads provides a facile and reliable strategy for the site-specific modification of nanobodies. This method exhibits high catalytic activity, good reusability, and universality, simplifies protein purification, and reduces the loss of nanobody bioconjugates effectively. It enables site-specific conjugation of nanobodies, facilitating targeted immunofluorescence imaging and improved in vivo circulation dynamics.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Chemistry, Applied
Zihang Cheng, Nannan Li, Zhining Chen, Kaikai Li, Dongling Qiao, Siming Zhao, Binjia Zhang
Summary: A high-fat diet is a risk factor for many chronic diseases, and ingesting retrograded starch can help manage hyperlipidemia symptoms by reducing triglyceride and LDL cholesterol levels. The intervention of retrograded starch was found to increase the relative abundance of Bacteroides, which produce propionic acid and had a positive correlation with butyric acid that has anti-inflammatory functions. Thus, retrograded starch intervention may regulate the body's health by altering intestinal bacteria.
Review
Biochemistry & Molecular Biology
Ruifeng Wang, Xin Shi, Kaikai Li, Alex Bunker, Chunmei Li
Summary: One distinguishing feature of the persimmon is its high proanthocyanidins content, known as persimmon tannin (PT), which has many health benefits. This review aims to summarize the literature on the relationship between PT structure and activity, as well as the potential mechanisms underlying its health benefits. The unique structure of PT and its conversion into oligomeric proanthocyanidins, along with its effects on lipogenic and inflammatory signaling pathways, fatty acid oxidation, gut microbiota, and absorption properties, contribute to its multiple health benefits.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Mechanical
Kaikai Li, Longsheng Lu, Yingxi Xie, Min Yu, Guoxiang Jiang, Jinwei Kou, Jiao Gao
Summary: In order to improve the cutting performance of electrosurgical units, an oil-infused surface (OIS) was fabricated and applied to the work terminal. The OIS showed excellent antifouling and thermal barrier properties, enabling autonomous sliding behavior of plasma droplets and reducing tissue adhesive and thermal damage during cutting.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2023)
Article
Engineering, Multidisciplinary
Longsheng Lu, Guoxiang Jiang, Kaikai Li, Yingxi Xie, Jiao Gao
Summary: Learning from nature, particularly from the purple orchid leaf, is a promising approach to design superhydrophobic surfaces. By analyzing the wettability difference of the leaf as it grows and its relation to surface morphology, it is found that the presence of well-developed micro-scale basic unit bumps with a dense nano-scale waxy layer contributes to the best hydrophobicity of the mature leaf. The study also demonstrates that the nano-waxy layer is more effective in enhancing surface wettability than the micro-bumps.
JOURNAL OF BIONIC ENGINEERING
(2023)
Article
Chemistry, Physical
Kaikai Li, Yingxi Xie, Biao Tang, Huanwen Ding, Xiaokang Mei, Min Yu, Chunbao Li, Longsheng Lu
Summary: By constructing surface microstructures and improving their hydrophobicity, severe adhesion of biological fluids on surgical electrodes can be effectively reduced. Inspired by purple orchid leaves with self-cleaning properties, the dynamic behavior of water and biological droplets on superhydrophobic microstructured surfaces (SMSs) heated over 100°C was studied. The SMSs with Cassie-Baxter state showed a pseudo-Leidenfrost effect for water droplets, and the dynamic evolution mechanism of plasma droplets on heated surfaces was proposed. The findings contribute to understanding the anti-adhesion mechanism of surgical electrodes at the microscopic level.
SURFACES AND INTERFACES
(2023)
Review
Metallurgy & Metallurgical Engineering
Wei Liu, Chen Wanqi, Ma Menghan, Li Kailun
Summary: Tungsten is a promising material for plasma facing in nuclear fusion reactors due to its advantageous properties. However, exposure to plasma can lead to micro/nanoscale damage on its surface, impacting its thermal and mechanical properties. This paper provides an overview of the research on the damage behavior of tungsten exposed to plasma, including the mechanisms of surface blistering and the effects of irradiation defects. The findings can contribute to optimizing the microstructure of tungsten materials and improving their performance and lifespan.
ACTA METALLURGICA SINICA
(2023)
