Metabolic Engineering of Escherichia coli for High-Yield Production of (R)-1,3-Butanediol

In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design

(2020) Ashty S. Karim et al.   Nature Chemical Biology

Bacterial synthesis of C3-C5 diols via extending amino acid catabolism

(2020) Jian Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Engineering of Escherichia coli for De Novo Production of 1,5-Pentanediol from Glucose

(2020) Xuecong Cen et al.   ACS Synthetic Biology

Systems-level engineering and characterization of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB)

(2019) Renato de Souza Pinto Lemgruber et al.   METABOLIC ENGINEERING

Metabolic Engineering of a Homoserine-Derived Non-Natural Pathway for the De Novo Production of 1,3-Propanediol from Glucose

(2019) Weiqun Zhong et al.   ACS Synthetic Biology

The role of the acyl-CoA thioesterase “YciA” in the production of (R)-3-hydroxybutyrate by recombinant Escherichia coli

(2019) Mónica Guevara-Martínez et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic engineering for the synthesis of polyesters: A 100-year journey from polyhydroxyalkanoates to non-natural microbial polyesters

(2019) So Young Choi et al.   METABOLIC ENGINEERING

Production of ethylene glycol from xylose by metabolically engineered Escherichia coli

(2018) Tong Un Chae et al.   AICHE JOURNAL

Engineering a short, aldolase-based pathway for ( R )-1,3-butanediol production in Escherichia coli

(2018) Kayla Nemr et al.   METABOLIC ENGINEERING

Rational engineering of diol dehydratase enables 1,4-butanediol biosynthesis from xylose

(2017) Jia Wang et al.   METABOLIC ENGINEERING

Conversion of Furfural to 1,5-Pentanediol: Process Synthesis and Analysis

(2017) Kefeng Huang et al.   ACS Sustainable Chemistry & Engineering

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids

(2017) Anna N. Khusnutdinova et al.   Biotechnology Journal

Cofactor recycling for co-production of 1,3-propanediol and glutamate by metabolically engineered Corynebacterium glutamicum

(2017) Jinhai Huang et al.   Scientific Reports

Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

(2016) Zhen Chen et al.   Biotechnology for Biofuels

Development of a commercial scale process for production of 1,4-butanediol from sugar

(2016) Anthony Burgard et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic engineering of Corynebacterium glutamicum for the de novo production of ethylene glycol from glucose

(2016) Zhen Chen et al.   METABOLIC ENGINEERING

Increasing the production of (R)-3-hydroxybutyrate in recombinant Escherichia coli by improved cofactor supply

(2016) Mariel Perez-Zabaleta et al.   Microbial Cell Factories

Controlling Citrate Synthase Expression by CRISPR/Cas9 Genome Editing for n-Butanol Production in Escherichia coli

(2016) Min-Ji Heo et al.   ACS Synthetic Biology

Metabolic engineering of Escherichia coli using CRISPR–Cas9 meditated genome editing

(2015) Yifan Li et al.   METABOLIC ENGINEERING

Autonomous production of 1,4-butanediol via a de novo biosynthesis pathway in engineered Escherichia coli

(2015) Huaiwei Liu et al.   METABOLIC ENGINEERING

Biorefineries for the production of top building block chemicals and their derivatives

(2015) Sol Choi et al.   METABOLIC ENGINEERING

Enhancement of (R)-1,3-butanediol production by engineeredEscherichia coliusing a bioreactor system with strict regulation of overall oxygen transfer coefficient and pH

(2014) Naoya Kataoka et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Engineering of a butyraldehyde dehydrogenase ofClostridium saccharoperbutylacetonicumto fit an engineered 1,4-butanediol pathway inEscherichia coli

(2014) Hee Jin Hwang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microbial production of short chain diols

(2014) Yudong Jiang et al.   Microbial Cell Factories

Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum

(2013) Zhen Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Directed Evolution and Structural Analysis of NADPH-Dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) Reductase from Ralstonia eutropha Reveals Two Mutations Responsible for Enhanced Kinetics

(2013) Ken'ichiro Matsumoto et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improvement of (R)-1,3-butanediol production by engineered Escherichia coli

(2013) Naoya Kataoka et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Bio-based production of C2-C6 platform chemicals

(2012) Yu-Sin Jang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities

(2012) M. K. Akhtar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial production of diols as platform chemicals: Recent progresses

(2011) An-Ping Zeng et al.   CURRENT OPINION IN BIOTECHNOLOGY

Systems metabolic engineering for chemicals and materials

(2011) Jeong Wook Lee et al.   TRENDS IN BIOTECHNOLOGY

Engineering of Corynebacterium glutamicum with an NADPH-Generating Glycolytic Pathway for L-Lysine Production

(2010) S. Takeno et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Glycerol: A promising and abundant carbon source for industrial microbiology

(2008) Gervásio Paulo da Silva et al.   BIOTECHNOLOGY ADVANCES