Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

Disruption of the Reductive 1,3-Propanediol Pathway Triggers Production of 1,2-Propanediol for Sustained Glycerol Fermentation by Clostridium pasteurianum

(2016) Michael E. Pyne et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic engineering of enhanced glycerol-3-phosphate synthesis to increase lipid production in Synechocystis sp. PCC 6803

(2016) Xi Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lipid production from biodiesel-derived crude glycerol by Rhodosporidium fluviale DMKU-RK253 using temperature shift with high cell density

(2016) Pirapan Polburee et al.   BIOCHEMICAL ENGINEERING JOURNAL

A biorefinery approach to microbial oil production from glycerol by Rhodotorula glutinis

(2016) Eleni E. Karamerou et al.   BIOMASS & BIOENERGY

Effects of mutation of 2,3-butanediol formation pathway on glycerol metabolism and 1,3-propanediol production by Klebsiella pneumoniae J2B

(2016) Vinod Kumar et al.   BIORESOURCE TECHNOLOGY

Value-added processing of crude glycerol into chemicals and polymers

(2016) Xiaolan Luo et al.   BIORESOURCE TECHNOLOGY

Protein engineering approaches to chemical biotechnology

(2016) Zhen Chen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic engineering of Corynebacterium glutamicum for the de novo production of ethylene glycol from glucose

(2016) Zhen Chen et al.   METABOLIC ENGINEERING

Employing bacterial microcompartment technology to engineer a shell-free enzyme-aggregate for enhanced 1,2-propanediol production in Escherichia coli

(2016) Matthew J. Lee et al.   METABOLIC ENGINEERING

Integrated analysis of gene expression and metabolic fluxes in PHA-producing Pseudomonas putida grown on glycerol

(2016) Veronique Beckers et al.   Microbial Cell Factories

High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii

(2016) Veerle E. T. Maervoet et al.   Microbial Cell Factories

Optimum Rebalancing of the 3-Hydroxypropionic Acid Production Pathway from Glycerol in Escherichia coli

(2016) Hyun Gyu Lim et al.   ACS Synthetic Biology

l-Lactate Production from Biodiesel-Derived Crude Glycerol by Metabolically Engineered Enterococcus faecalis: Cytotoxic Evaluation of Biodiesel Waste and Development of a Glycerol-Inducible Gene Expression System

(2015) Yuki Doi   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Efficient production of 1,3-butadiene in the catalytic dehydration of 2,3-butanediol

(2015) Hailing Duan et al.   APPLIED CATALYSIS A-GENERAL

Metabolic engineering of Klebsiella pneumoniae for the de novo production of 2-butanol as a potential biofuel

(2015) Zhen Chen et al.   BIORESOURCE TECHNOLOGY

High production of 2,3-butanediol from biodiesel-derived crude glycerol by metabolically engineered Klebsiella oxytoca M1

(2015) Sukhyeong Cho et al.   Biotechnology for Biofuels

Enhancement of glycerol metabolism in the oleaginous marine diatom Fistulifera solaris JPCC DA0580 to improve triacylglycerol productivity

(2015) Masaki Muto et al.   Biotechnology for Biofuels

A systematic analysis of TCAEscherichia colimutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source

(2015) Antonio Valle et al.   Biotechnology Journal

Systematic Engineering of Escherichia coli for d-Lactate Production from Crude Glycerol

(2015) Zei Wen Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipid production by yeasts growing on biodiesel-derived crude glycerol: strain selection and impact of substrate concentration on the fermentation efficiency

(2015) S.S. Tchakouteu et al.   JOURNAL OF APPLIED MICROBIOLOGY

Metabolic Engineering of Klebsiella pneumoniae for the Production of 2-Butanone from Glucose

(2015) Zhen Chen et al.   PLoS One

A systematic analysis of TCAEscherichia colimutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source

(2015) Antonio Valle et al.   Biotechnology Journal

Microaerobic Conversion of Glycerol to Ethanol in Escherichia coli

(2014) Matthew S. Wong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Development of a deletion mutant of Pseudomonas denitrificans that does not degrade 3-hydroxypropionic acid

(2014) Shengfang Zhou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of optically pure d -lactate from glycerol by engineered Klebsiella pneumoniae strain

(2014) Xinjun Feng et al.   BIORESOURCE TECHNOLOGY

Enhanced production of 3-hydroxypropionic acid from glycerol by modulation of glycerol metabolism in recombinant Escherichia coli

(2014) Kwangwook Kim et al.   BIORESOURCE TECHNOLOGY

Metabolic engineering of 3-hydroxypropionic acid biosynthesis inEscherichia coli

(2014) Hun Su Chu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein design and engineering of a de novo pathway for microbial production of 1,3-propanediol from glucose

(2014) Zhen Chen et al.   Biotechnology Journal

Elevated production of 3-hydroxypropionic acid by metabolic engineering of the glycerol metabolism in Escherichia coli

(2014) Won Seok Jung et al.   METABOLIC ENGINEERING

Metabolic engineering of Escherichia coli for efficient free fatty acid production from glycerol

(2014) Hui Wu et al.   METABOLIC ENGINEERING

A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase

(2014) Rajesh Reddy Bommareddy et al.   METABOLIC ENGINEERING

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

(2014) Kento Tokuyama et al.   Microbial Cell Factories

Improvement of L-phenylalanine production from glycerol by recombinant Escherichia coli strains: The role of extra copies of glpK, glpX, and tktA genes

(2014) Katrin Gottlieb et al.   Microbial Cell Factories

1-Butanol production from glycerol by engineered Klebsiella pneumoniae

(2014) Miaomiao Wang et al.   RSC Advances

Butanol production from glycerol by recombinant Escherichia coli

(2013) Pengpeng Zhou et al.   ANNALS OF MICROBIOLOGY

Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum

(2013) Zhen Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Recent advances in the metabolic engineering of microorganisms for the production of 3-hydroxypropionic acid as C3 platform chemical

(2013) Kris Niño G. Valdehuesa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Crude glycerol-based production of amino acids and putrescine by Corynebacterium glutamicum

(2013) Tobias M. Meiswinkel et al.   BIORESOURCE TECHNOLOGY

Production of 3-hydroxypropionic acid from glycerol by recombinantPseudomonas denitrificans

(2013) Shengfang Zhou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Production of 2-butanol from crude glycerol by a genetically-engineered Klebsiella pneumoniae strain

(2013) Baek-Rock Oh et al.   BIOTECHNOLOGY LETTERS

Fermentation of glycerol and production of valuable chemical and biofuel molecules

(2013) Anu Jose Mattam et al.   BIOTECHNOLOGY LETTERS

Efficient bioconversion of crude glycerol from biodiesel to optically pured-lactate by metabolically engineered Escherichia coli

(2013) Xian-zhong Chen et al.   GREEN CHEMISTRY

Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli

(2013) Suman Mazumdar et al.   Microbial Cell Factories

Glycerol: Production, consumption, prices, characterization and new trends in combustion

(2013) César A.G. Quispe et al.   RENEWABLE & SUSTAINABLE ENERGY REVIEWS

Glycerol production and its applications as a raw material: A review

(2013) H.W. Tan et al.   RENEWABLE & SUSTAINABLE ENERGY REVIEWS

Rational Design of Allosteric Regulation of Homoserine Dehydrogenase by a Nonnatural Inhibitor l-Lysine

(2013) Zhen Chen et al.   ACS Synthetic Biology

Synthesis of Pure meso-2,3-Butanediol from Crude Glycerol Using an Engineered Metabolic Pathway in Escherichia coli

(2012) Soojin Lee et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Study and reengineering of the binding sites and allosteric regulation of biosynthetic threonine deaminase by isoleucine and valine in Escherichia coli

(2012) Lin Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production

(2012) Feng Geng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Advances in biotechnological production of 1,3-propanediol

(2012) Guneet Kaur et al.   BIOCHEMICAL ENGINEERING JOURNAL

Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions

(2012) Yanna Huang et al.   BIORESOURCE TECHNOLOGY

Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources

(2012) Ethan I. Lan et al.   BIORESOURCE TECHNOLOGY

Production of 3-hydroxypropionic acid from glycerol by recombinantKlebsiella pneumoniaeΔdhaTΔyqhDwhich can produce vitamin B12naturally

(2012) Somasundar Ashok et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biodiesel biorefinery: opportunities and challenges for microbial production of fuels and chemicals from glycerol waste

(2012) João R M Almeida et al.   Biotechnology for Biofuels

Effect of puuC overexpression and nitrate addition on glycerol metabolism and anaerobic 3-hydroxypropionic acid production in recombinant Klebsiella pneumoniae ΔglpKΔdhaT

(2012) Somasundar Ashok et al.   METABOLIC ENGINEERING

Anaerobic fermentation of glycerol: a platform for renewable fuels and chemicals

(2012) James M. Clomburg et al.   TRENDS IN BIOTECHNOLOGY

A Synthetic Biology Approach to Engineer a Functional Reversal of the β-Oxidation Cycle

(2012) James M. Clomburg et al.   ACS Synthetic Biology

Glycerol conversion to 1, 3-Propanediol is enhanced by the expression of a heterologous alcohol dehydrogenase gene in Lactobacillus reuteri

(2012) Hema Vaidyanathan et al.   AMB Express

Glycerol as a substrate for aerobic succinate production in minimal medium withCorynebacterium glutamicum

(2012) Boris Litsanov et al.   Microbial Biotechnology

Optimization of Culture Conditions for 1,3-Propanediol Production from Glycerol Using a Mutant Strain of Klebsiella pneumoniae

(2011) Baek-Rock Oh et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Metabolic pathway analysis of 1,3-propanediol production with a genetically modified Klebsiella pneumoniae by overexpressing an endogenous NADPH-dependent alcohol dehydrogenase

(2011) Zhen Chen et al.   BIOCHEMICAL ENGINEERING JOURNAL

Quantitative analysis of the fermentative metabolism of glycerol in Escherichia coli

(2011) Angela Cintolesi et al.   BIOTECHNOLOGY AND BIOENGINEERING

An Experimentally Validated Genome-Scale Metabolic Reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228

(2011) Y.-C. Liao et al.   JOURNAL OF BACTERIOLOGY

Production of 1,2-Propanediol from Glycerol in Saccharomyces cerevisiae

(2011) Joon-Young Jung   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

(2011) Harry Yim et al.   Nature Chemical Biology

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

(2011) Robert J. Conrado et al.   NUCLEIC ACIDS RESEARCH

Escherichia coli Strains Engineered for Homofermentative Production of D-Lactic Acid from Glycerol

(2010) S. Mazumdar et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fermentation of Glycerol to Succinate by Metabolically Engineered Strains of Escherichia coli

(2010) X. Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Debottlenecking the 1,3-propanediol pathway by metabolic engineering

(2010) E. Celińska   BIOTECHNOLOGY ADVANCES

Metabolic engineering of Escherichia coli for the production of 1,2-propanediol from glycerol

(2010) James M. Clomburg et al.   BIOTECHNOLOGY AND BIOENGINEERING

A process for microbial hydrocarbon synthesis: Overproduction of fatty acids inEscherichia coliand catalytic conversion to alkanes

(2010) Rebecca M. Lennen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microbial production and applications of 1,2-propanediol

(2010) R. K. Saxena et al.   INDIAN JOURNAL OF MICROBIOLOGY

Metabolic engineering of Escherichia coli for the production of succinate from glycerol

(2010) Matthew D. Blankschien et al.   METABOLIC ENGINEERING

Microbial Conversion of Glycerol to 1,3-Propanediol by an Engineered Strain of Escherichia coli

(2009) X. Tang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolism in 1,3-propanediol fed-batch fermentation by a D-lactate deficient mutant ofKlebsiella pneumoniae

(2009) Yun-Zhen Xu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic pathway analysis of glycerol metabolism inKlebsiella pneumoniaeincorporating oxygen regulatory system

(2009) Qingrui Zhang et al.   BIOTECHNOLOGY PROGRESS

Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes

(2009) Zhen Chen et al.   ENZYME AND MICROBIAL TECHNOLOGY

Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis

(2009) Margarita Salazar et al.   MOLECULAR GENETICS AND GENOMICS

Engineering of a Glycerol Utilization Pathway for Amino Acid Production by Corynebacterium glutamicum

(2008) D. Rittmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineering Escherichia coli for the efficient conversion of glycerol to ethanol and co-products

(2008) Syed Shams Yazdani et al.   METABOLIC ENGINEERING

Overproduction of free fatty acids in E. coli: Implications for biodiesel production

(2008) Xuefeng Lu et al.   METABOLIC ENGINEERING

Introduction of an NADH regeneration system into Klebsiella oxytoca leads to an enhanced oxidative and reductive metabolism of glycerol

(2008) Yanping Zhang et al.   METABOLIC ENGINEERING