Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct

Thalamus Modulates Consciousness via Layer-Specific Control of Cortex

(2020) Michelle J. Redinbaugh et al.   NEURON

Dynamic Regional Brain Atrophy Rates in the First Year After Ischemic Stroke

(2020) Amy Brodtmann et al.   STROKE

Microglia and Their Promising Role in Ischemic Brain Injuries: An Update

(2020) Luting Yu et al.   Frontiers in Cellular Neuroscience

Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke

(2020) Hong-Ru Chen et al.   Science Advances

The role of macrophages in the resolution of inflammation

(2019) Satoshi Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Cross‐talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury

(2018) Jesica Frik et al.   EMBO REPORTS

Post-Thalamic Stroke Movement Disorders: A Systematic Review

(2018) Navnika Gupta et al.   EUROPEAN NEUROLOGY

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Sensorimotor stroke alters hippocampo-thalamic network activity

(2018) Philipp Baumgartner et al.   Scientific Reports

Single-Cell RNA-Seq Uncovers a Robust Transcriptional Response to Morphine by Glia

(2018) Denis Avey et al.   Cell Reports

Microglial cell loss after ischemic stroke favors brain neutrophil accumulation

(2018) Amaia Otxoa-de-Amezaga et al.   ACTA NEUROPATHOLOGICA

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Osteopontin Attenuates Secondary Neurodegeneration in the Thalamus after Experimental Stroke

(2018) Anne Ladwig et al.   Journal of Neuroimmune Pharmacology

Memantine attenuates cell apoptosis by suppressing the calpain-caspase-3 pathway in an experimental model of ischemic stroke

(2017) Bin Chen et al.   EXPERIMENTAL CELL RESEARCH

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Old Maids: Aging and Its Impact on Microglia Function

(2017) Edward Koellhoffer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Human Thalamus Is an Integrative Hub for Functional Brain Networks

(2017) Kai Hwang et al.   JOURNAL OF NEUROSCIENCE

Hypoxia Response Element-Regulated MMP-9 Promotes Neurological Recovery via Glial Scar Degradation and Angiogenesis in Delayed Stroke

(2017) Hongxia Cai et al.   MOLECULAR THERAPY

The diversity and disparity of the glial scar

(2017) Katrina L. Adams et al.   NATURE NEUROSCIENCE

Reactive astrogliosis in stroke: Contributions of astrocytes to recovery of neurological function

(2017) Neil R. Sims et al.   NEUROCHEMISTRY INTERNATIONAL

Transcriptomic analysis reveals differential activation of microglial genes after ischemic stroke in mice

(2017) Akbar Khan et al.   NEUROSCIENCE

The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy

(2017) Andrea Becerra-Calixto et al.   Frontiers in Molecular Neuroscience

Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation

(2017) Arjun Sapkota et al.   PLoS One

TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke

(2017) Zhijuan Cao et al.   Scientific Reports

Thalamic pathology and memory loss in early Alzheimer’s disease: moving the focus from the medial temporal lobe to Papez circuit

(2016) John P. Aggleton et al.   BRAIN

Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation

(2016) Francesc Miró-Mur et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic stress exposure following photothrombotic stroke is associated with increased levels of Amyloid beta accumulation and altered oligomerisation at sites of thalamic secondary neurodegeneration in mice

(2016) Lin Kooi Ong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography

(2016) Ana Moraga et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of Cathepsin B Alleviates Secondary Degeneration in Ipsilateral Thalamus After Focal Cerebral Infarction in Adult Rats

(2016) Xialin Zuo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Astrocytic response to cerebral ischemia is influenced by sex differences and impaired by aging

(2016) Nioka C. Chisholm et al.   NEUROBIOLOGY OF DISEASE

Microglia Priming with Aging and Stress

(2016) Anzela Niraula et al.   NEUROPSYCHOPHARMACOLOGY

Prefrontal Ischemia in the Rat Leads to Secondary Damage and Inflammation in Remote Gray and White Matter Regions

(2016) Nina Weishaupt et al.   Frontiers in Neuroscience

Chronic stress exacerbates neuronal loss associated with secondary neurodegeneration and suppresses microglial-like cells following focal motor cortex ischemia in the mouse

(2015) Kimberley A. Jones et al.   BRAIN BEHAVIOR AND IMMUNITY

Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia

(2015) Ana Moraga et al.   Journal of Neuroinflammation

Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage

(2015) Gregory Scott et al.   Journal of Neuroinflammation

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Thalamic structures and associated cognitive functions: Relations with age and aging

(2015) Rosemary Fama et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The role of microglia and myeloid immune cells in acute cerebral ischemia

(2015) Corinne Benakis et al.   Frontiers in Cellular Neuroscience

Animal Models of Aging Research: Implications for Human Aging and Age-Related Diseases

(2015) Sarah J. Mitchell et al.   Annual Review of Animal Biosciences

Glial Scar Formation Occurs in the Human Brain after Ischemic Stroke

(2014) Lijie Huang et al.   International Journal of Medical Sciences

The Dichotomy of Memantine Treatment for Ischemic Stroke: Dose-Dependent Protective and Detrimental Effects

(2014) Melissa Trotman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A comprehensive thalamocortical projection map at the mesoscopic level

(2014) Barbara J Hunnicutt et al.   NATURE NEUROSCIENCE

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage

(2013) Roslyn A. Taylor et al.   Clinical & Developmental Immunology

Differential effects of aging and sex on stroke induced inflammation across the lifespan

(2013) Bharti Manwani et al.   EXPERIMENTAL NEUROLOGY

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

(2013) I. B. Wanner et al.   JOURNAL OF NEUROSCIENCE

Age-related changes in brain support cells: Implications for stroke severity

(2013) Farida Sohrabji et al.   NEUROCHEMISTRY INTERNATIONAL

In and out from the cortex: Development of major forebrain connections

(2013) E. Leyva-Díaz et al.   NEUROSCIENCE

The ischemic penumbra: how does tissue injury evolve?

(2012) Wolf-Dieter Heiss   Annals of the New York Academy of Sciences

Executive Summary: Heart Disease and Stroke Statistics—2012 Update

(2012) et al.   CIRCULATION

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

A Morphological Analysis of Thalamocortical Axon Fibers of Rat Posterior Thalamic Nuclei: A Single Neuron Tracing Study with Viral Vectors

(2011) Sachi Ohno et al.   CEREBRAL CORTEX

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Neurogenesis and Angiogenesis within the Ipsilateral Thalamus with Secondary Damage after Focal Cortical Infarction in Hypertensive Rats

(2009) Li Ling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE