Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit

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(2020) Hongbao Yang et al.   Molecular Cancer

circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma

(2020) JunFeng Wang et al.   Cell Death & Disease

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(2020) Wei Hu et al.   Molecular Cancer

Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation

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Treg-dependent immunosuppression triggers effector T cell dysfunction via the STING/ILC2 axis

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(2019) Yaxiong Zhang et al.   Molecular Cancer

The novel roles of circRNAs in human cancer

(2019) Qingfeng Shang et al.   Molecular Cancer

Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift

(2019) Jung Eun Park et al.   ONCOGENE

The Intersection between Tumor Angiogenesis and Immune Suppression

(2019) Osama E. Rahma et al.   CLINICAL CANCER RESEARCH

TAMing pancreatic cancer: combat with a double edged sword

(2019) Manendra Babu Lankadasari et al.   Molecular Cancer

Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer

(2019) Xiuyuan Chen et al.   Autophagy

The Tumor Microenvironment Innately Modulates Cancer Progression

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Exosomal circRNAs: biogenesis, effect and application in human diseases

(2019) Yangxia Wang et al.   Molecular Cancer

AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells

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Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer

(2019) Subir Biswas et al.   JOURNAL OF IMMUNOLOGY

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637

(2019) Yanli Zhang et al.   EBioMedicine

Carboplatin chemoresistance is associated with CD11b+/Ly6C+ myeloid release and upregulation of TIGIT and LAG3/CD160 exhausted T cells

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Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation

(2018) Xiyue Yang et al.   FASEB JOURNAL

Circular RNAs function as ceRNAs to regulate and control human cancer progression

(2018) Yaxian Zhong et al.   Molecular Cancer

Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C

(2018) Vincent L. Cannataro et al.   ONCOGENE

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma

(2018) Genwen Chen et al.   Cell Death & Disease

Macrophages orchestrate breast cancer early dissemination and metastasis

(2018) Nina Linde et al.   Nature Communications

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

(2018) Tomer Cooks et al.   Nature Communications

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

(2018) Christopher Groth et al.   BRITISH JOURNAL OF CANCER

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Circular RNA hsa_circ_0003221 (circPTK2) promotes the proliferation and migration of bladder cancer cells

(2017) Zhen-Qiang Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

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(2017) Fred R Hirsch et al.   LANCET

CircRNA: functions and properties of a novel potential biomarker for cancer

(2017) Shujuan Meng et al.   Molecular Cancer

Circular RNAs in human cancer

(2017) Yumin Wang et al.   Molecular Cancer

exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes

(2017) Shengli Li et al.   NUCLEIC ACIDS RESEARCH

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

The impact of hypoxia on tumor-associated macrophages

(2016) Anne-Theres Henze et al.   JOURNAL OF CLINICAL INVESTIGATION

Exosomes and tumor-mediated immune suppression

(2016) Theresa L. Whiteside   JOURNAL OF CLINICAL INVESTIGATION

M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

(2015) Marie Genin et al.   BMC CANCER

MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells

(2015) Paul Zarogoulidis et al.   CELLULAR SIGNALLING

Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

(2015) Stefano Ugel et al.   JOURNAL OF CLINICAL INVESTIGATION

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE