Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells

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The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in cellular metabolism and cancer

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Structure of the Atg101–Atg13 complex reveals essential roles of Atg101 in autophagy initiation

(2015) Hironori Suzuki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

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(2015) Candia M. Kenific et al.   TRENDS IN CELL BIOLOGY

Structure of the Atg101–Atg13 complex reveals essential roles of Atg101 in autophagy initiation

(2015) Hironori Suzuki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

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p62/SQSTM1 synergizes with autophagy for tumor growth in vivo

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HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death

(2014) Nieves Peltzer et al.   Cell Reports

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Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation

(2013) Fei Liu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD

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FIP200 is required for maintenance and differentiation of postnatal neural stem cells

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Function of Focal Adhesion Kinase Scaffolding to Mediate Endophilin A2 Phosphorylation Promotes Epithelial-Mesenchymal Transition and Mammary Cancer Stem Cell Activitiesin Vivo

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Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

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Autophagy: Renovation of Cells and Tissues

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Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

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Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

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FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

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Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development

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Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

(2009) Chun-Chi Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Inactivation of FIP200 Leads to Inflammatory Skin Disorder, but Not Tumorigenesis, in Conditional Knock-out Mouse Models

(2008) Huijun Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

FIP200, a key signaling node to coordinately regulate various cellular processes

(2007) Boyi Gan et al.   CELLULAR SIGNALLING