SARS-CoV-2 infection initiates interleukin-17-enriched transcriptional response in different cells from multiple organs

Mediators of SARS-CoV-2 entry are preferentially enriched in cardiomyocytes

(2021) Jing Yang et al.   HEREDITAS

Title: ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway

(2021) Xiaoyuan Lin et al.   iScience

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

COVID-19 and the cardiovascular system

(2020) Ying-Ying Zheng et al.   Nature Reviews Cardiology

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

The Variety of Cardiovascular Presentations of COVID-19

(2020) Justin A. Fried et al.   CIRCULATION

Characterization of an asymptomatic cohort of SARS-COV-2 infected individuals outside of Wuhan, China

(2020) Yubo Wang et al.   CLINICAL INFECTIOUS DISEASES

Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China

(2020) Bo Li et al.   Clinical Research in Cardiology

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

(2020) Yijin Wang et al.   JOURNAL OF HEPATOLOGY

Tocilizumab treatment in COVID-19: A single center experience

(2020) Pan Luo et al.   JOURNAL OF MEDICAL VIROLOGY

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

(2020) Kelvin Kai-Wang To et al.   LANCET INFECTIOUS DISEASES

Association of a Province-Wide Intervention With Salt Intake and Hypertension in Shandong Province, China, 2011-2016

(2020) Aiqiang Xu et al.   JAMA Internal Medicine

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

(2020) Meng-Yuan Li et al.   Infectious Diseases of Poverty

Potential Effects of Coronaviruses on the Cardiovascular System

(2020) Mohammad Madjid et al.   JAMA Cardiology

Liver injury in COVID-19: management and challenges

(2020) Chao Zhang et al.   Lancet Gastroenterology & Hepatology

Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

(2020) Abigail Vanderheiden et al.   JOURNAL OF VIROLOGY

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles

(2020) Akshamal M. Gamage et al.   PLoS Pathogens

Evidence of SARS-CoV-2 Transcriptional Activity in Cardiomyocytes of COVID-19 Patients without Clinical Signs of Cardiac Involvement

(2020) Gaetano Pietro Bulfamante et al.   Biomedicines

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

(2019) Rudragouda Channappanavar et al.   JOURNAL OF CLINICAL INVESTIGATION

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

L1000FWD: fireworks visualization of drug-induced transcriptomic signatures

(2018) Zichen Wang et al.   BIOINFORMATICS

Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro

(2018) Jin Shin et al.   Viruses-Basel

LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent

(2018) Hyun-Wook Han et al.   Scientific Reports

Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

(2018) Anqi Zhu et al.   BIOINFORMATICS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection - clinicopathological and ultrastructural study

(2017) Khaled O Alsaad et al.   HISTOPATHOLOGY

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Viral Load Kinetics of MERS Coronavirus Infection

(2016) Myoung-don Oh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

(2016) P. S. Pillai et al.   SCIENCE

Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection

(2014) Julie Dyall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aging Impairs IFN Regulatory Factor 7 Up-Regulation in Plasmacytoid Dendritic Cells during TLR9 Activation

(2014) H. W. Stout-Delgado et al.   JOURNAL OF IMMUNOLOGY

Interleukin-6 (IL-6) and IL-17 Synergistically Promote Viral Persistence by Inhibiting Cellular Apoptosis and Cytotoxic T Cell Function

(2014) W. Hou et al.   JOURNAL OF VIROLOGY

Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus

(2013) Abdullah Assiri et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of Host Immune Response and Viral Load in the Differential Outcome of Pandemic H1N1 (2009) Influenza Virus Infection in Indian Patients

(2010) Vidya A. Arankalle et al.   PLoS One

Aging Promotes Neutrophil-Induced Mortality by Augmenting IL-17 Production during Viral Infection

(2009) Heather W. Stout-Delgado et al.   Cell Host & Microbe