ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish

Imaging epilepsy in larval zebrafish

(2020) D.R.W. Burrows et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions

(2020) Pierre Coste de Bagneaux et al.   PLoS Genetics

CaImAn an open source tool for scalable calcium imaging data analysis

(2019) Andrea Giovannucci et al.   eLife

Chemical Stimulation of Renal Tissue Induces Sympathetic Activation and a Pressor Response via the Paraventricular Nucleus in Rats

(2019) Chao Ye et al.   Neuroscience Bulletin

Targeted knockout of GABA-A receptor gamma 2 subunit provokes transient light-induced reflex seizures in zebrafish larvae

(2019) Meijiang Liao et al.   Disease Models & Mechanisms

Ultrafast Two-Photon Imaging of a High-Gain Voltage Indicator in Awake Behaving Mice

(2019) Vincent Villette et al.   CELL

DPP-4 Inhibitor Linagliptin is Neuroprotective in Hyperglycemic Mice with Stroke via the AKT/mTOR Pathway and Anti-apoptotic Effects

(2019) Gang Zhang et al.   Neuroscience Bulletin

Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development

(2018) Amrutha Swaminathan et al.   CURRENT BIOLOGY

Neuropathological profile of the pentylenetetrazol (PTZ) kindling model

(2018) E. Samokhina et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

DEPDC5 takes a second hit in familial focal epilepsy

(2018) Matthew P. Anderson   JOURNAL OF CLINICAL INVESTIGATION

A mouse model of DEPDC5 -related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

(2018) Christopher J. Yuskaitis et al.   NEUROBIOLOGY OF DISEASE

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

(2018) Hortense de Calbiac et al.   Annals of Clinical and Translational Neurology

UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling

(2018) Hefei Zhang et al.   PLoS Genetics

NoRMCorre: An online algorithm for piecewise rigid motion correction of calcium imaging data

(2017) Eftychios A. Pnevmatikakis et al.   JOURNAL OF NEUROSCIENCE METHODS

mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis

(2017) Chloë Scheldeman et al.   NEUROBIOLOGY OF DISEASE

Depdc5 knockout rat: A novel model of mTORopathy

(2016) Elise Marsan et al.   NEUROBIOLOGY OF DISEASE

Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo

(2016) Thomas Deneux et al.   Nature Communications

Neurological and neuropsychiatric aspects of tuberous sclerosis complex

(2015) Paolo Curatolo et al.   LANCET NEUROLOGY

Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test

(2015) Fengjiao Chen et al.   NEUROPHARMACOLOGY

Rapamycin suppresses PTZ-induced seizures at different developmental stages of zebrafish

(2015) Anna Maria Siebel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

mTOR Signaling in Epilepsy: Insights from Malformations of Cortical Development

(2015) P. B. Crino   Cold Spring Harbor Perspectives in Medicine

TORC1-dependent epilepsy caused by acute biallelicTsc1deletion in adult mice

(2013) Elisabeth Abs et al.   ANNALS OF NEUROLOGY

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

(2013) L. Bar-Peled et al.   SCIENCE

Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Origin of excitation underlying locomotion in the spinal circuit of zebrafish

(2012) E. Eklof-Ljunggren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs

(2011) Wolfgang Löscher   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish

(2008) K. Asakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE