Nanocarrier-Mediated Topical Insulin Delivery for Wound Healing

Silver Nanoparticles: Synthesis and Application for Nanomedicine

(2019) Sang Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Insulin Mucoadhesive Liposomal Gel for Wound Healing: a Formulation with Sustained Release and Extended Stability Using Quality by Design Approach

(2019) Marwa H. S. Dawoud et al.   AAPS PHARMSCITECH

Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing

(2019) Satish Patel et al.   BIOMEDICINE & PHARMACOTHERAPY

Particle toxicology and health - where are we?

(2019) Michael Riediker et al.   Particle and Fibre Toxicology

Healing of Diabetic Foot Ulcers in Patients Treated at the Copenhagen Wound Healing Center in 1999/2000 and in 2011/2012

(2019) Marie Louise Buhl Sørensen et al.   Journal of Diabetes Research

Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends

(2019) Federica Paladini et al.   Materials

Wound healing related agents: Ongoing research and perspectives

(2018) Konstantina Kaplani et al.   ADVANCED DRUG DELIVERY REVIEWS

In-Vivo Anti-Diabetic and Wound Healing Effect of Antioxidant Gold Nanoparticles Synthesized Using Insulin Plant ( Chamaecostus Cuspidatus )

(2018) M. Ponnanikajamideen et al.   Canadian Journal of Diabetes

Effect of poly(ethylene glycol) on insulin stability and cutaneous cell proliferation in vitro following cytoplasmic delivery of insulin-loaded nanoparticulate carriers – A potential topical wound management approach

(2018) Dalia H. Abdelkader et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

In vitro and in vivo study of PCL/COLL wound dressing loaded with insulin-chitosan nanoparticles on cutaneous wound healing in rats model

(2018) Arian Ehterami et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Enhanced cutaneous wound healing in rats following topical delivery of insulin-loaded nanoparticles embedded in poly(vinyl alcohol)-borate hydrogels

(2018) Dalia H. Abdelkader et al.   Drug Delivery and Translational Research

Alginate in Wound Dressings

(2018) et al.   Pharmaceutics

Novel nano-insulin formulation modulates cytokine secretion and remodeling to accelerate diabetic wound healing

(2018) Pawandeep Kaur et al.   Nanomedicine-Nanotechnology Biology and Medicine

HA metabolism in skin homeostasis and inflammatory disease

(2017) Rafaela-Maria Kavasi et al.   FOOD AND CHEMICAL TOXICOLOGY

Nanoengineered silica: Properties, applications and toxicity

(2017) Andrea M. Mebert et al.   FOOD AND CHEMICAL TOXICOLOGY

Insulin complexed with cyclodextrins stimulates epithelialization and neovascularization of skin wound healing in rats

(2017) Jean Carlos Fernando Besson et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Burns

(2017) Colton B. Nielson et al.   Journal of Burn Care & Research

Functionalized silk fibroin dressing with topical bioactive insulin release for accelerated chronic wound healing

(2017) Xiufang Li et al.   Materials Science & Engineering C-Materials for Biological Applications

Advanced Growth Factor Delivery Systems in Wound Management and Skin Regeneration

(2017) Jin Park et al.   MOLECULES

An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery

(2017) Munawar Mohammed et al.   Pharmaceutics

Effect of Topical Insulin on Second-Degree Burns in Diabetic Rats

(2016) F. Azevedo et al.   Biological Research for Nursing

Infection in Venous Leg Ulcers: Considerations for Optimal Management in the Elderly

(2016) Douglas J. Pugliese   DRUGS & AGING

Annealing as a tool for the optimization of lyophilization and ensuring of the stability of protein-loaded PLGA nanoparticles

(2016) Pedro Fonte et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

“The Good, the Bad and the Ugly” of Chitosans

(2016) Barbara Bellich et al.   Marine Drugs

Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

(2016) Pedro Fonte et al.   PHARMACEUTICAL RESEARCH

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Biomedical Applications of Biodegradable Polyesters

(2016) Iman Manavitehrani et al.   Polymers

Preventing foot ulcers

(2016) Kerry May   Australian Prescriber

Becaplermin gel in the treatment of diabetic neuropathic foot ulcers

(2016) Nikolaos Papanas   Clinical Interventions in Aging

Polymer-based nanoparticles for oral insulin delivery: Revisited approaches

(2015) Pedro Fonte et al.   BIOTECHNOLOGY ADVANCES

Release of insulin from PLGA-alginate dressing stimulates regenerative healing of burn wounds in rats

(2015) S. Dhall et al.   CLINICAL SCIENCE

Chitosan as a starting material for wound healing applications

(2015) V. Patrulea et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Liposomes as nanomedical devices

(2015) Giuseppina Bozzuto et al.   International Journal of Nanomedicine

The topical administration of rhEGF-loaded nanostructured lipid carriers (rhEGF-NLC) improves healing in a porcine full-thickness excisional wound model

(2015) Garazi Gainza et al.   JOURNAL OF CONTROLLED RELEASE

Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review

(2015) M.Abd Elgadir et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

(2015) Aimee E. Krausz et al.   Nanomedicine-Nanotechnology Biology and Medicine

Advances in drug delivery systems (DDSs) to release growth factors for wound healing and skin regeneration

(2015) Garazi Gainza et al.   Nanomedicine-Nanotechnology Biology and Medicine

siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

(2015) Pratik S. Randeria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring

(2015) Meilang Xue et al.   Advances in Wound Care

Challenges in the Treatment of Chronic Wounds

(2015) Robert G. Frykberg et al.   Advances in Wound Care

Evaluation of silica nanoparticle toxicity after topical exposure for 90 days

(2014) Seong Soo A. An et al.   International Journal of Nanomedicine

A novel strategy for the treatment of chronic wounds based on the topical administration of rhEGF-loaded lipid nanoparticles: In vitro bioactivity and in vivo effectiveness in healing-impaired db/db mice

(2014) Garazi Gainza et al.   JOURNAL OF CONTROLLED RELEASE

Wound healing activity of Origanum vulgare engineered titanium dioxide nanoparticles in Wistar Albino rats

(2014) Renu Sankar et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Clinical application of growth factors and cytokines in wound healing

(2014) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms

(2013) T Velnar et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Functionalization of gauzes with liposomes entrapping an anti-inflammatory drug: A strategy to improve wound healing

(2013) Helena Ferreira et al.   REACTIVE & FUNCTIONAL POLYMERS

Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications

(2013) Bogumiła Reidy et al.   Materials

Liposomes as sterile preparations and limitations of sterilisation techniques in liposomal manufacturing

(2013) Ming-Ren Toh et al.   Asian Journal of Pharmaceutical Sciences

Severe Injury Is Associated With Insulin Resistance, Endoplasmic Reticulum Stress Response, and Unfolded Protein Response

(2012) Marc G. Jeschke et al.   ANNALS OF SURGERY

Alginate-PEG Sponge Architecture and Role in the Design of Insulin Release Dressings

(2012) Michael Hrynyk et al.   BIOMACROMOLECULES

Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing

(2012) Srinivasulu Chigurupati et al.   BIOMATERIALS

Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticals

(2012) Carmelo Puglia et al.   Expert Opinion on Drug Delivery

The structure and function of the stratum corneum

(2012) Gopinathan K. Menon et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial

(2012) Maria H. M. Lima et al.   PLoS One

Microfabricated particulate drug-delivery systems

(2011) Jing Pan et al.   Biotechnology Journal

Biomedical applications of biodegradable polymers

(2011) Bret D. Ulery et al.   JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS

Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing

(2011) Karen H.L. Kwan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Intensive insulin treatment increases donor site wound protein synthesis in burn patients

(2011) Demidmaa Tuvdendorj et al.   SURGERY

Human pilot studies reveal the potential of a vitronectin: growth factor complex as a treatment for chronic wounds

(2011) Zee Upton et al.   International Wound Journal

Intensive Insulin Therapy in Severely Burned Pediatric Patients

(2010) Marc G. Jeschke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evaluation of the bacterial diversity of Pressure ulcers using bTEFAP pyrosequencing

(2010) Drake M Smith et al.   BMC Medical Genomics

Silver Nanoparticles Mediate Differential Responses in Keratinocytes and Fibroblasts during Skin Wound Healing

(2010) Xuelai Liu et al.   ChemMedChem

Intensive insulin therapy improves insulin sensitivity and mitochondrial function in severely burned children*

(2010) Ricki Y. Fram et al.   CRITICAL CARE MEDICINE

Sustained prolonged topical delivery of bioactive human insulin for potential treatment of cutaneous wounds

(2010) Michael Hrynyk et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanotechnology tools in pharmaceutical R&D

(2010) Challa S.S.R. Kumar   Materials Today

Wound Healing Primer

(2010) Stephanie R. Goldberg et al.   SURGICAL CLINICS OF NORTH AMERICA

Cell and molecular mechanisms of keratinocyte function stimulated by insulin during wound healing

(2009) Yan Liu et al.   BMC CELL BIOLOGY

Hybrid hyaluronan hydrogel encapsulating nanogel as a protein nanocarrier: New system for sustained delivery of protein with a chaperone-like function

(2009) Tai Hirakura et al.   JOURNAL OF CONTROLLED RELEASE

Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery

(2009) Mei Lin Tan et al.   PEPTIDES

Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors

(2009) Cristina Borselli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adverse Effects of Titanium Dioxide Nanoparticles on Human Dermal Fibroblasts and How to Protect Cells

(2009) Zhi Pan et al.   Small

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Silver nanoparticles as a new generation of antimicrobials

(2008) Mahendra Rai et al.   BIOTECHNOLOGY ADVANCES

The biology of chronic foot ulcers in persons with diabetes

(2008) R. Gary Sibbald et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Liposomes and skin: From drug delivery to model membranes

(2008) G.M. El Maghraby et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products

(2008) Jana Pardeike et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Role for Topical Insulin in the Management Problematic Surgical Wounds

(2008) JM Wilson et al.   ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND