Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues
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Title
Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-25
DOI
10.1038/s41467-021-23395-3
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Note: Only part of the references are listed.- The regulation of Yorkie, YAP and TAZ: new insights into the Hippo pathway
- (2020) Samuel A. Manning et al. DEVELOPMENT
- YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice
- (2020) Mark A. Rudolf et al. JOURNAL OF NEUROSCIENCE
- Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal
- (2020) Ksenia Gnedeva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo
- (2019) Tanner O. Monroe et al. DEVELOPMENTAL CELL
- The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming
- (2019) Elda M. Rueda et al. Cell Reports
- pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components
- (2019) Federico Marini et al. BMC BIOINFORMATICS
- Structure-based rational design of staurosporine-based fluorescent probe with broad-ranging kinase affinity for kinase panel application
- (2019) Yoshihiko Hirozane et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Identification of Quinolinols as Activators of TEAD-Dependent Transcription
- (2019) Ajaybabu V. Pobbati et al. ACS Chemical Biology
- ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors
- (2018) Upul K. Bandarage et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- YAP/TAZ upstream signals and downstream responses
- (2018) Antonio Totaro et al. NATURE CELL BIOLOGY
- Therapeutic approaches for cardiac regeneration and repair
- (2018) Hisayuki Hashimoto et al. Nature Reviews Cardiology
- Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas
- (2018) Kai Yao et al. NATURE
- Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
- (2018) Iván M. Moya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Aminoglycoside Damage and Hair Cell Regeneration in the Chicken Utricle
- (2017) Mirko Scheibinger et al. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
- Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
- (2017) Yuka Morikawa et al. NATURE
- The extracellular matrix protein agrin promotes heart regeneration in mice
- (2017) Elad Bassat et al. NATURE
- Development and regeneration of vestibular hair cells in mammals
- (2017) Joseph C. Burns et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti
- (2017) Jinshu Xu et al. Nature Communications
- Elastic force restricts growth of the murine utricle
- (2017) Ksenia Gnedeva et al. eLife
- The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
- (2016) Toshiro Moroishi et al. CELL
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea
- (2016) Wenli Ni et al. JOURNAL OF NEUROSCIENCE
- Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration
- (2016) Fuqin Fan et al. Science Translational Medicine
- Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy
- (2016) Wen Juan et al. Genes
- Neuronal cell cycle: the neuron itself and its circumstances
- (2015) José M Frade et al. CELL CYCLE
- A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
- (2015) Toshiro Moroishi et al. GENES & DEVELOPMENT
- Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
- (2015) Jung-Soon Mo et al. NATURE CELL BIOLOGY
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- SoxC transcription factors are essential for the development of the inner ear
- (2015) Ksenia Gnedeva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
- (2015) Yuka Morikawa et al. Science Signaling
- Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear
- (2015) Joseph C. Burns et al. Nature Communications
- Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
- (2015) Yuka Morikawa et al. Science Signaling
- Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo
- (2014) B. C. Cox et al. DEVELOPMENT
- Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse
- (2014) Marcia M. Mellado Lagarde et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia
- (2014) Jerry Silver et al. Cold Spring Harbor Perspectives in Biology
- Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
- (2014) Xiufeng Zhong et al. Nature Communications
- The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
- (2013) Randy Johnson et al. NATURE REVIEWS DRUG DISCOVERY
- Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors
- (2013) Fuxin Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Over Half the Hair Cells in the Mouse Utricle First Appear After Birth, with Significant Numbers Originating from Early Postnatal Mitotic Production in Peripheral and Striolar Growth Zones
- (2012) Joseph C. Burns et al. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
- The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition
- (2012) Wei Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hair Cell Replacement in Adult Mouse Utricles after Targeted Ablation of Hair Cells with Diphtheria Toxin
- (2012) J. S. Golub et al. JOURNAL OF NEUROSCIENCE
- In Vivo Proliferative Regeneration of Balance Hair Cells in Newborn Mice
- (2012) J. C. Burns et al. JOURNAL OF NEUROSCIENCE
- Quantifying the chemical beauty of drugs
- (2012) G. Richard Bickerton et al. Nature Chemistry
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea
- (2012) R. Chai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
- (2011) Karin Schlegelmilch et al. CELL
- Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice
- (2011) Katrin Arnold et al. Cell Stem Cell
- E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
- (2011) N.-G. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
- (2010) Nailing Zhang et al. DEVELOPMENTAL CELL
- The challenge of hair cell regeneration
- (2010) Andrew K Groves EXPERIMENTAL BIOLOGY AND MEDICINE
- Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis
- (2009) Danzhi Huang et al. BIOINFORMATICS
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- The nuts and bolts of AGC protein kinases
- (2009) Laura R. Pearce et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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