α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-18
DOI
10.1038/s41467-021-24039-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research
- (2020) Senthil T. Kumar et al. JOURNAL OF NEUROCHEMISTRY
- Defining α-synuclein species responsible for Parkinson disease phenotypes in mice
- (2019) Jessica M. Froula et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
- (2018) Michele Perni et al. ACS Chemical Biology
- The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases
- (2018) Nunilo Cremades et al. NEUROBIOLOGY OF DISEASE
- α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
- (2018) Marthe H. R. Ludtmann et al. Nature Communications
- Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers
- (2018) Daniel R. Whiten et al. Cell Reports
- Cryo-EM structure of alpha-synuclein fibrils
- (2018) Ricardo Guerrero-Ferreira et al. eLife
- Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons
- (2018) Jordi Pujols et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
- (2018) Binsen Li et al. Nature Communications
- Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
- (2018) Ji-Eun Lee et al. NANO LETTERS
- Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril Assembly
- (2017) Ersilia De Lorenzi et al. JOURNAL OF ALZHEIMERS DISEASE
- Prying into the Prion Hypothesis for Parkinson's Disease
- (2017) Patrik Brundin et al. JOURNAL OF NEUROSCIENCE
- α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies
- (2017) Yvette C Wong et al. NATURE MEDICINE
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
- (2017) Giuliana Fusco et al. SCIENCE
- The Synucleinopathies: Twenty Years On
- (2017) Michel Goedert et al. Journal of Parkinsons Disease
- AlphaLISA detection of alpha-synuclein in the cerebrospinal fluid and its potential application in Parkinson’s disease diagnosis
- (2017) Hongli Zhao et al. Protein & Cell
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure
- (2016) Patrizia Marinelli et al. Scientific Reports
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
- (2015) Benjamin Dehay et al. LANCET NEUROLOGY
- Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
- (2015) Serene W. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants
- (2015) Laura Tosatto et al. Scientific Reports
- Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease
- (2013) Jens Wagner et al. ACTA NEUROPATHOLOGICA
- α-Synucleinopathy phenotypes
- (2013) Heather McCann et al. PARKINSONISM & RELATED DISORDERS
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early Aggregation Steps in α-Synuclein as Measured by FCS and FRET: Evidence for a Contagious Conformational Change
- (2010) Sangeeta Nath et al. BIOPHYSICAL JOURNAL
- Detection of elevated levels of -synuclein oligomers in CSF from patients with Parkinson disease
- (2010) T. Tokuda et al. NEUROLOGY
- The chemistry and biology of LL-37
- (2009) Matthew F. Burton et al. NATURAL PRODUCT REPORTS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now