Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization
Authors
Keywords
-
Journal
ACS Medicinal Chemistry Letters
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2021-09-07
DOI
10.1021/acsmedchemlett.1c00432
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The promising role of antibody drug conjugate in cancer therapy: Combining targeting ability with cytotoxicity effectively
- (2021) Wen‐Qian Li et al. Cancer Medicine
- Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model
- (2020) Zhaoming Huang et al. OncoTargets and Therapy
- Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments
- (2020) Verena Henrichs et al. Nature Communications
- Association of mitochondria with microtubules inhibits mitochondrial fission by precluding assembly of the fission protein Dnm1
- (2019) Kritika Mehta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Orchestrating mitochondria in neurons: Cytoskeleton as the conductor
- (2019) Carlos Cardanho‐Ramos et al. Cytoskeleton
- Synthesis and Evaluation of Dolastatin 10 Analogues Containing Heteroatoms on the Amino Acid Side Chains
- (2017) Julien Dugal-Tessier et al. JOURNAL OF NATURAL PRODUCTS
- Synthesis and biological activity evaluation of dolastatin 10 analogues with N-terminal modifications
- (2017) Xin Wang et al. TETRAHEDRON
- Microtubule-Based Transport and the Distribution, Tethering, and Organization of Organelles
- (2017) Kari Barlan et al. Cold Spring Harbor Perspectives in Biology
- New insight on the structural features of the cytotoxic auristatins MMAE and MMAF revealed by combined NMR spectroscopy and quantum chemical modelling
- (2017) Mikael P. Johansson et al. Scientific Reports
- Biolabile peptidyl delivery systems toward sequential drug release
- (2016) Elena Ragozin et al. BIOPOLYMERS
- Dual-drug RGD conjugates provide enhanced cytotoxicity to melanoma and non-small lung cancer cells
- (2016) Y. Gilad et al. BIOPOLYMERS
- Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma
- (2016) Boris Redko et al. Oncotarget
- The anti-angiogenic effect and novel mechanisms of action of Combretastatin A-4
- (2016) Min Su et al. Scientific Reports
- Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP–Monomethyl Auristatin E Conjugates
- (2015) Kelly E. Burns et al. MOLECULAR PHARMACEUTICS
- Design and synthesis of analogues of natural products
- (2015) Martin E. Maier ORGANIC & BIOMOLECULAR CHEMISTRY
- Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications
- (2014) Andreas Maderna et al. JOURNAL OF MEDICINAL CHEMISTRY
- Microtubule-binding agents: a dynamic field of cancer therapeutics
- (2010) Charles Dumontet et al. NATURE REVIEWS DRUG DISCOVERY
- Stereoselective synthesis of the dolastatin units by organotrifluoroborates additions to α-amino aldehydes
- (2007) Rodrigo Cella et al. TETRAHEDRON LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started