Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI

Acute kidney injury and maladaptive tubular repair leading to renal fibrosis

(2020) Samuel M.-W. Yu et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Pathophysiology of AKI to CKD progression

(2020) Yuki Sato et al.   SEMINARS IN NEPHROLOGY

Knockdown of YAP inhibits growth in Hep-2 laryngeal cancer cells via epithelial-mesenchymal transition and the Wnt/β-catenin pathway

(2019) Xiaomin Tang et al.   BMC CANCER

RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress

(2019) Muya Lin et al.   BRAIN RESEARCH BULLETIN

Tubular GM-CSF Promotes Late MCP-1/CCR2-Mediated Fibrosis and Inflammation after Ischemia/Reperfusion Injury

(2019) Leyuan Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hepatocyte Stress Increases Expression of YAP and TAZ in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis

(2019) Meghan Mooring et al.   HEPATOLOGY

Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption

(2019) Jun Liu et al.   PLOS BIOLOGY

YAP in Kupffer cells enhances the production of pro‐inflammatory cytokines and promotes the development of non‐alcoholic steatohepatitis

(2019) Kyoungsub Song et al.   HEPATOLOGY

The inhibition of Hippo/Yap signaling pathway is required for magnesium isoglycyrrhizinate to ameliorate hepatic stellate cell inflammation and activation

(2018) Li Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Epithelial Cell Cycle Behaviour in the Injured Kidney

(2018) Lies Moonen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury

(2018) Yu Gu et al.   Journal of Translational Medicine

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

MicroRNA-493 targets STMN-1 and promotes hypoxia-induced epithelial cell cycle arrest in G2/M and renal fibrosis

(2018) Ting Liu et al.   FASEB JOURNAL

EGF Receptor–Dependent YAP Activation Is Important for Renal Recovery from AKI

(2018) Jianchun Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

(2018) Thijs J. Hagenbeek et al.   Science Signaling

Porous Se@SiO2 nanospheres attenuate ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and inflammation by antioxidative stress

(2018) Zhihuang Zheng et al.   International Journal of Nanomedicine

Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma

(2017) Wantae Kim et al.   GUT

Renal recovery after acute kidney injury

(2017) L. G. Forni et al.   INTENSIVE CARE MEDICINE

Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction

(2017) Vimal Ramjee et al.   JOURNAL OF CLINICAL INVESTIGATION

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

(2016) Toshiro Moroishi et al.   CELL

Monocyte chemoattractant protein-1 and the kidney

(2016) Hermann Haller et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Tubular Epithelial NF- B Activity Regulates Ischemic AKI

(2016) L. Marko et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways

(2016) Biao Ma et al.   Nature Communications

The photosensitizer verteporfin has light-independent anti-leukemic activity for Ph-positive acute lymphoblastic leukemia and synergistically works with dasatinib

(2016) Takanobu Morishita et al.   Oncotarget

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector

(2015) J. Xu et al.   CLINICAL SCIENCE

Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments

(2015) D. P. Basile et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression

(2015) M. A. Venkatachalam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps

(2015) H. Rabb et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD

(2015) David A. Ferenbach et al.   Nature Reviews Nephrology

Severe Renal Mass Reduction Impairs Recovery and Promotes Fibrosis after AKI

(2014) A. J. Polichnowski et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells

(2013) Hui Cai et al.   Cell Communication and Signaling

The Hippo pathway: regulators and regulations

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury

(2012) Dominic P. Del Re et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yes, AKI Truly Leads to CKD

(2012) C.-y. Hsu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles

(2011) Toru Yoshitomi et al.   BIOMATERIALS

Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury

(2011) Ion D. Bucaloiu et al.   KIDNEY INTERNATIONAL

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Sauchinone reduces oxygen-glucose deprivation-evoked neuronal cell death via suppression of intracellular radical production

(2009) In Young Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH