Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia

Role of the Lipid Membrane and Membrane Proteins in Tau Pathology

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Mitochondrial ROS control neuronal excitability and cell fate in frontotemporal dementia

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Novel tau filament fold in corticobasal degeneration

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Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase

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Optical monitoring of glutamate release at multiple synapses in situ detects changes following LTP induction

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Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium

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LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia

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Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure

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Clustering of Tau fibrils impairs the synaptic composition of α3‐Na+/K+‐ATPase and AMPA receptors

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Membrane-mediated fibrillation and toxicity of the tau hexapeptide PHF6

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Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death

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Trafficking mechanisms underlying Nav channel subcellular localization in neurons

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Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule-associated protein tau mutations which displays several phenotypes linked to neurodegeneration

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Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes

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Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

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Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

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Neuronal hyperexcitability in a mouse model ofSCN8Aepileptic encephalopathy

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Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

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CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons

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Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology

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Calcium Signalling Toolkits in Astrocytes and Spatio-Temporal Progression of Alzheimer's Disease

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Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

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Using Human iPSC-Derived Neurons to Model TAU Aggregation

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Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients withMAPTmutations

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Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT

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Pathological Tau Disrupts Ongoing Network Activity

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An autopsied case of unclassifiable sporadic four-repeat tauopathy presenting with parkinsonism and speech disturbances

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Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

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A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy

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Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

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Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

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Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

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White Matter Tauopathy With Globular Glial Inclusions: A Distinct Sporadic Frontotemporal Lobar Degeneration

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Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

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Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

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