Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT

Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2

(2014) C. Carpentier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Human stem cell models of dementia

(2014) F. J. Livesey   HUMAN MOLECULAR GENETICS

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons

(2014) Elizabeth M. Hartfield et al.   PLoS One

The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons

(2013) Mariangela Iovino et al.   ACTA NEUROPATHOLOGICA

Embryonic Stem Cell–Based Modeling of Tau Pathology in Human Neurons

(2013) Jerome Mertens et al.   AMERICAN JOURNAL OF PATHOLOGY

Variation in tau isoform expression in different brain regions and disease states

(2013) Elisa Majounie et al.   NEUROBIOLOGY OF AGING

Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells

(2013) Helen Fong et al.   Stem Cell Reports

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

(2012) Daniah Trabzuni et al.   HUMAN MOLECULAR GENETICS

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

(2012) Rickie Patani et al.   JOURNAL OF NEUROCHEMISTRY

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

(2012) Yichen Shi et al.   Nature Protocols

Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research

(2012) Selina Wray et al.   PLoS One

Mis-splicing of Tau exon 10 in myotonic dystrophy type 1 is reproduced by overexpression of CELF2 but not by MBNL1 silencing

(2011) C.M. Dhaenens et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8A

(2011) Janelle E. O'Brien et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

(2010) Mariangela Iovino et al.   PLoS One

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

(2009) Will Stoothoff et al.   JOURNAL OF NEUROCHEMISTRY

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

(2008) A. Kalsotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus

(2007) Tara M. Caffrey et al.   NEUROBIOLOGY OF AGING