Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

(2021) Simon Alberti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

(2021) Laura Mediani et al.   EMBO REPORTS

Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation

(2021) Jinge Gu et al.   CELL RESEARCH

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

(2021) Youngdae Gwon et al.   SCIENCE

Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

(2020) Zhenying Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles

(2020) Jinge Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nucleolus functions as a phase-separated protein quality control compartment

(2019) F. Frottin et al.   SCIENCE

PhaSepDB: a database of liquid–liquid phase separation related proteins

(2019) Kaiqiang You et al.   NUCLEIC ACIDS RESEARCH

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

(2018) Lin Guo et al.   CELL

Quality Control of Membraneless Organelles

(2018) Simon Alberti et al.   JOURNAL OF MOLECULAR BIOLOGY

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism

(2016) Massimo Ganassi et al.   MOLECULAR CELL

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE