PTPN3 is a potential target for a new cancer immunotherapy that has a dual effect of T cell activation and direct cancer inhibition in lung neuroendocrine tumor

Neuronal Cav3 channelopathies: recent progress and perspectives

(2020) Philippe Lory et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor

(2019) Akiko Fujimura et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Patched 1-interacting Peptide Represses Fibrosis in Pancreatic Cancer to Augment the Effectiveness of Immunotherapy

(2019) Yasuhiro Oyama et al.   JOURNAL OF IMMUNOTHERAPY

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

(2018) Giorgia Rota et al.   Cell Reports

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Outcomes of patients with large cell neuroendocrine carcinoma of the lung after complete resection

(2017) Ke Han et al.   Translational Cancer Research

CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells

(2016) Kumi Suyama et al.   CANCER LETTERS

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

(2016) Ying-Nan P. Chen et al.   NATURE

Protein tyrosine phosphatase PTPN3 promotes drug resistance and stem cell-like characteristics in ovarian cancer

(2016) Shuqin Li et al.   Scientific Reports

MAPK pathway mediates epithelial-mesenchymal transition induced by paraquat in alveolar epithelial cells

(2015) Min Huang et al.   ENVIRONMENTAL TOXICOLOGY

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD8+ and FOXP3+ Tumor-Infiltrating T Cells Before and After Chemoradiotherapy for Rectal Cancer

(2014) Eiji Shinto et al.   ANNALS OF SURGICAL ONCOLOGY

Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer

(2014) Shojiro Matsushita et al.   CANCER SCIENCE

Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation

(2014) M-Y Li et al.   ONCOGENE

Effect of myeloperoxidase inhibition on gene expression profiles in HL-60 cells exposed to 1, 2, 4,-benzenetriol

(2014) Emiko Miyahara et al.   TOXICOLOGY

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

(2013) Taku Okazaki et al.   NATURE IMMUNOLOGY

Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions

(2011) Toshitatsu Ogino et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis

(2011) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Survival and prognostic factors in small cell lung cancer

(2009) Jian Li et al.   MEDICAL ONCOLOGY

EGFR Signals to mTOR Through PKC and Independently of Akt in Glioma

(2009) Q.-W. Fan et al.   Science Signaling